Keywords:
Medicine
;
Internal medicine
;
Hematology
;
Cytology
;
Medicine & Public Health
;
Cytology
;
Hematology
;
Internal medicine
;
Medicine
;
Thrombosis
;
Hemostasis
;
Blood Coagulation Disorders
Description / Table of Contents:
Thrombotic and thromboembolic disorders, in particular, thrombosis complicating life style-related diseases such as malignancies and arterioscleosis resulting from diabetes mellitus, hypertension, obesity and others, are now, more than ever, the leading causes of morbidity and mortality and become the common medico-social problem with economic consequences in the industrialized and developing countries. The impact of molecular biology and genetics on thrombosis and hemostasis is rapidly growing, and greatly expanded information in this field also provide further extension on regeneration and development of tissues/organs/embryos and bio-regulatory mechanisms in viable tissues against intrinsic and extrinsic stimuli, in addition to cardiovascular diseases. With this edition, not only the up-dated molecular biology and genetics but also the clinical implications into further comprehensions of pathophysiology, novel exploitation of diagnostic methodologies and therapeutic applications, and methods for prevention in thrombosis-hemostasis and their-related disorders including atherosclerosis are covered. The basic and clinical researchers in non-Japanese countries, particularly Asian-Pacific ones as well as Japan will feel deeply interested.
Type of Medium:
Online Resource
Pages:
1 Online-Ressource (XXI, 643 Seiten)
,
Illustrationen
ISBN:
9784431788478
Series Statement:
SpringerLink
URL:
https://doi.org/10.1007/978-4-431-78847-8
URL:
http://dx.doi.org/10.1007/978-4-431-78847-8
URL:
https://swbplus.bsz-bw.de/bsz305570811cov.jpg
DOI:
10.1007/978-4-431-78847-8
Language:
English
Note:
Includes bibliographical references and index
,
Structure and Functions of Fibrinogen and Fibrin; Vitamin K Cycles and .-Carboxylation of Coagulation Factors; Synthesis and Secretion of Coagulation Factor VIII; Structure and Biological Function of Factor XI; Structural Insights into the Life History of Thrombin; A Molecular Model of the Human Prothrombinase Complex; Lipid Mediators and Tissue Factor Expression; Tissue Factor Pathway Inhibitor: Structure and Function; Biology of an Antithrombotic Factor-ADAMTS13; Antithrombin and Heparin Cofactor II: Structure and Functions
,
High-Mobility Group Box 1: Missing Link Between Thrombosis and Inflammation?Coagulation, Inflammation, and Tissue Remodeling; Structure and Function of the Endothelial Cell Protein C Receptor; New Aspects of Antiinflammatory Activity of Antithrombin: Molecular Mechanism(s) and Therapeutic Implications; Platelet Collagen Receptors; Positive and Negative Regulation of Integrin Function; GPIb-Related Signaling Pathways in Platelets; Sphingosine 1-Phosphate as a Platelet-Derived Bioactive Lipid; Polymorphisms of Platelet Membrane Glycoproteins
,
Platelet Procoagulant Activity Appeared by Exposure of Platelets to Blood Flow ConditionsRegulation of Cellular uPA Activity and Its Implication in Pathogenesis of Diseases; Role of tPA in the Neural System; Role of Fibrinolysis in the Nasal System; Role of Fibrinolysis in Hepatic Regeneration; Pathophysiology of Transglutaminases Including Factor FXIII; A Linkage in the Developmental Pathway of Vascular and Hematopoietic Cells; Atherosclerosis and Angiogenesis: Double Face of Neovascularization in Atherosclerotic Intima and Collateral Vessels in Ischemic Organs; Hemophilia A and Inhibitors
,
von Willebrand Disease: Diagnosis and TreatmentAge-Related Homeostasis and Hemostatic System; Molecular Evolution of Blood Clotting Factors with Special Reference to Fibrinogen and von Willebrand Factor; Snake Venoms and Other Toxic Components Affecting Thrombosis and Hemostasis; Structures and Potential Roles of Oligosaccharides in Human Coagulation Factors and von Willebrand Factor; Hypercoagulable States; Etiopathology of the Antiphospholipid Syndrome; Malignancy and Thrombosis; Disseminated Intravascular Coagulation; Current Clinical Status of Venous Thromboembolism in Japan
,
Platelet Activity and Antiplatelet Therapy in Patients with Ischemic Stroke and Transient Ischemic AttackClinical Role of Recombinant Factor Vlla in Bleeding Disorders; Clinical Role of Protein S Deficiency in Asian Population; Atherothrombosis and Thrombus Propagation; Thrombotic Microangiopathy;
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