In:
PLOS ONE, Public Library of Science (PLoS), Vol. 18, No. 8 ( 2023-8-14), p. e0289830-
Abstract:
People with tuberculosis (TB) are often lost to follow-up during treatment transition to another facility. These losses may result in substantial morbidity and mortality but are rarely recorded. We conducted a record review on adults diagnosed with TB at 11 hospitals in Limpopo, South Africa, who were subsequently transferred to a local clinic to initiate or continue treatment. We then performed in-depth record reviews at the primary care clinic to which they were referred and called participants who could not be identified as starting treatment. Between August 2017 and April 2018, we reviewed records of 778 individuals diagnosed with TB in-hospital and later referred to local clinics for treatment. Of the 778, 88 (11%) did not link to care, and an additional 43 (5.5%) died. Compared to people without cough, those with cough had higher odds of linking to care (aOR = 2.01, 95% CI: 1.26–3.25, p = 0.005) and were also linked more quickly [adjusted Time Ratio (aTR) = 0.53, 95% CI:0.36–0.79, p 〈 0.001], as were those diagnosed microbiologically (aOR = 1.86, 95% CI: 1.16–3.06, p = 0.012; aTR = 0.58, 95% CI: 0.34–0.98, p = 0.04). People diagnosed with TB in hospitals often disengage following referral to local clinics. Interventions to identify and re-engage people who do not present to local clinics within days of referral might close an important gap in the TB treatment cascade.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0289830
DOI:
10.1371/journal.pone.0289830.g001
DOI:
10.1371/journal.pone.0289830.g002
DOI:
10.1371/journal.pone.0289830.g003
DOI:
10.1371/journal.pone.0289830.t001
DOI:
10.1371/journal.pone.0289830.t002
DOI:
10.1371/journal.pone.0289830.s001
DOI:
10.1371/journal.pone.0289830.s002
DOI:
10.1371/journal.pone.0289830.s003
DOI:
10.1371/journal.pone.0289830.s004
DOI:
10.1371/journal.pone.0289830.s005
DOI:
10.1371/journal.pone.0289830.s006
DOI:
10.1371/journal.pone.0289830.s007
DOI:
10.1371/journal.pone.0289830.s008
DOI:
10.1371/journal.pone.0289830.s009
DOI:
10.1371/journal.pone.0289830.s010
DOI:
10.1371/journal.pone.0289830.s011
DOI:
10.1371/journal.pone.0289830.s012
DOI:
10.1371/journal.pone.0289830.s013
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2023
detail.hit.zdb_id:
2267670-3
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