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  • Ovid Technologies (Wolters Kluwer Health)  (70)
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  • Ovid Technologies (Wolters Kluwer Health)  (70)
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  • English  (70)
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  • 1
    In: Alzheimer Disease & Associated Disorders, Ovid Technologies (Wolters Kluwer Health), Vol. 32, No. 1 ( 2018-01), p. 62-69
    Abstract: Semantic variant primary progressive aphasia (svPPA) has been associated with a variety of proteinopathies, mainly transactive response DNA-binding protein, but also with tau and β-amyloid. Recently selective tau tracers for positron emission tomography (PET) have been developed to determine the presence of cerebral tau deposits in vivo. Here, we investigated the topographical distribution of THK5351 in svPPA patients. Materials and Methods: Five svPPA patients, 14 Alzheimer’s disease patients, and 15 age-matched normal controls underwent [ 18 F]-THK5351 PET scans, magnetic resonance imaging, and detailed neuropsychological tests. [ 18 F]-fluorodeoxyglucose PET was obtained in 3 svPPA patients, whereas the remaining 2 underwent amyloid PET using [ 18 F]-flutemetamol. Tau distribution among the 3 groups was compared using regions of interest–based and voxel-based statistical analyses. Results: In svPPA patients, [ 18 F]-THK5351 retention was elevated in the anteroinferior and lateral temporal cortices compared with the normal controls group (left 〉 right), and in the left inferior and temporal polar region compared with Alzheimer’s disease patients. [ 18 F]-THK5351 retention inversely correlated with glucose metabolism, whereas regional THK retention correlated with clinical severity. [ 18 F]-flutemetamol scans were negative for β-amyloid. Conclusions: These findings show that [ 18 F]-THK5351 retention may be detected in cortical regions correlating with svPPA pathology.
    Type of Medium: Online Resource
    ISSN: 0893-0341
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2018
    detail.hit.zdb_id: 2048789-7
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  • 2
    In: Transplantation, Ovid Technologies (Wolters Kluwer Health), Vol. 104, No. 3 ( 2020-03), p. 460-466
    Abstract: This study aims to verify the condition of recipients of solid organs from donors with central nervous system (CNS) tumors and determine the risk of disease transmission due to transplantation. Methods. Twenty-eight brain-dead organ donors with CNS tumors and 91 recipients who received solid organs from January 1, 2005, to December 31, 2014 in Korea were investigated using the Korean Network of Organ Sharing data. Results. Of the 36 recipients of organs from the 11 donors whose pathological results were not verified, 4 developed the following tumors: renal cell carcinoma, carcinoma in situ of the cervix uteri, B-cell lymphoma, and colon cancer. Among 51 recipients from 17 donors with CNS tumor, no recipient had the same tumor as the donors. Six were classified as high-risk donors according to the World Health Organization classification, and 14 recipients from these donors did not develop tumor after transplantation. The remaining 11 donors were classified as low-risk donors according to the World Health Organization classification but as high-risk donors according to the Malignancy Subcommittee of the Disease Transmission Advisory Committee of the Organ Procurement and Transplantation Network/United Network for Organ Sharing. Of the 37 recipients, 3 had recurring hepatocellular carcinoma with lung and bone metastases, thyroid cancer, and Kaposi’s sarcoma after transplantation. Conclusions. The risk of disease transmission due to organ transplantation from donors with CNS tumors was very low. Thus, organ donation from such donors should be promoted actively to expand the donor range.
    Type of Medium: Online Resource
    ISSN: 0041-1337
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2020
    detail.hit.zdb_id: 2035395-9
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  • 3
    In: Liver Transplantation, Ovid Technologies (Wolters Kluwer Health), Vol. 16, No. 4 ( 2010-04), p. 513-519
    Type of Medium: Online Resource
    ISSN: 1527-6465
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2010
    detail.hit.zdb_id: 2002186-0
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  • 4
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  Transplantation Vol. 103, No. 11S ( 2019-11), p. S115-S115
    In: Transplantation, Ovid Technologies (Wolters Kluwer Health), Vol. 103, No. 11S ( 2019-11), p. S115-S115
    Type of Medium: Online Resource
    ISSN: 0041-1337
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2019
    detail.hit.zdb_id: 2035395-9
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  • 5
    In: Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 102, No. 22 ( 2023-06-02), p. e33961-
    Abstract: Plug-assisted retrograde transvenous obliteration (PARTO) or coil-assisted retrograde transvenous obliteration (CARTO) are alternative treatments for gastric variceal bleeding and hepatic encephalopathy. Both procedures have fewer complications related to balloon rupture or sclerosing agents and are shorter than balloon-occluded retrograde transvenous obliteration. Herein, we report a case of PARTO and CARTO was performed simultaneously to treat refractory hepatic encephalopathy in a patient with 2 portosystemic shunts. Patient concerns: A 59-year-old man with alcoholic liver cirrhosis presented to the emergency room with mental change. At presentation, the patient’s plasma ammonia level was 340 μg/dL. Diagnoses: A computed tomography scan revealed perisplenic collateral vessels and 2 splenorenal shunts. Intervention: PARTO and CARTO were performed to treat hepatic encephalopathy via the 2 splenorenal shunts. Outcomes: A follow-up computed tomography scan showed the splenorenal shunt was successfully embolized using a vascular plug and coil. After 3 weeks, the patient’s plasma ammonia level decreased to 80 μg/dL, and repeated hospitalizations due to hepatic encephalopathy ceased. Lessons: Depending on the patient’s anatomy, PARTO and CARTO can be performed simultaneously and, similar to balloon-occluded retrograde transvenous obliteration, are useful for treating hepatic encephalopathy.
    Type of Medium: Online Resource
    ISSN: 0025-7974
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2023
    detail.hit.zdb_id: 2049818-4
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  • 6
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2009
    In:  Journal of Cardiovascular Medicine Vol. 10, No. 12 ( 2009-12), p. 940-941
    In: Journal of Cardiovascular Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 10, No. 12 ( 2009-12), p. 940-941
    Type of Medium: Online Resource
    ISSN: 1558-2027
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2009
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  • 7
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Medicine Vol. 101, No. 49 ( 2022-12-9), p. e32013-
    In: Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 101, No. 49 ( 2022-12-9), p. e32013-
    Abstract: Plug-assisted retrograde tansvenous obliteration (PARTO) is commonly used to treat gastric variceal bleeding. PARTO is typically performed via the gastrorenal shunt or gastrocaval shunt and there have been no reports of PARTO performed through the pericardial vein in cases of gastric varices in which there is no gastrorenal or gastrocaval shunt. Herein, we report a case of PARTO was performed to treat gastric variceal bleeding in a patient with a gastric varix without a gastrorenal or gastrocaval shunt. Patient concerns: A 54-year-old man with alcoholic liver cirrhosis presented to the emergency room with hematemesis and melena. At presentation, the patient’s blood pressure was 130/70 mm Hg and hemoglobin level was 10.1 g/dL. Diagnoses: Computed tomography (CT) scan and endoscopic examination revealed a gastric varix at the gastric fundus. Interventions: PARTO was performed to treatment of gastric variceal bleeding via the pericardial vein. Outcomes: The patient did not show any signs of variceal bleeding after the procedure, and follow-up CT at 3 weeks showed complete resolution of the gastric varix. Lessons: Although PARTO is technically difficult to perform through pathways other than the gastrorenal or gastrocaval shunt, it can be a beneficial alternative in cases in which other treatments fail or are not feasible.
    Type of Medium: Online Resource
    ISSN: 1536-5964
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 2049818-4
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  • 8
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2022
    In:  Medicine Vol. 101, No. 52 ( 2022-12-30), p. e32447-
    In: Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 101, No. 52 ( 2022-12-30), p. e32447-
    Abstract: Vascular involvement manifests as aneurysms, stenosis, and arteriovenous malformations in patients with type I neurofibromatosis (NF-I). Aneurysms are rare; however, the renal artery is the most common site. Herein, we report a rare case of stent graft placement in an anterior tibial artery (ATA) pseudoaneurysm in a patient with NF-I. Patient concerns: A 52-year-old woman with NF-1 was admitted to the emergency room with painful swelling in the left lower leg. At presentation, the patient’s blood pressure was 100/60 mmHg and the hemoglobin level was 9 g/dL. Diagnoses: Computed tomography scan revealed a small aneurysm arising from the left ATA and an adjacent large hematoma. Intervention: Stent graft placement was performed to treat ATA pseudoaneurysm. Outcomes: After stent graft placement, the aneurysm disappeared and the distal flow was patent through the ATA. Lessons: Stent graft placement should be considered as another option for endovascular treatment in patients in whom coil embolization or surgery cannot be performed.
    Type of Medium: Online Resource
    ISSN: 1536-5964
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2022
    detail.hit.zdb_id: 2049818-4
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  • 9
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2018
    In:  Psychosomatic Medicine Vol. 80, No. 2 ( 2018-2), p. 193-199
    In: Psychosomatic Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 80, No. 2 ( 2018-2), p. 193-199
    Abstract: Patients with sleep-related breathing disorders are known to have more severe psychiatric symptoms than good sleepers. The aim of this study was to compare the psychiatric symptoms of participants with obstructive sleep apnea (OSA), those with simple snoring (SS), and normal controls (NC). Methods A total of 386 participants (260 with OSA, 75 with SS, and 51 NC) completed self-report questionnaires including the Symptoms Checklist 90-Revised and underwent nocturnal polysomnography. The scores of nine primary symptom dimensions and three global distress indices of the Symptoms Checklist 90-Revised were compared among the three groups, adjusting for age, sex, and body mass index. Results Participants with suspected OSA (OSA + SS) reported more severe psychiatric symptoms than the NC group. Compared with the participants with OSA, those with SS manifested more severe obsessive-compulsive (1.4 (1.0) versus 1.1 (0.7), p = .008) and depressive (1.2 (1.2) versus 0.8 (0.8), p = .031) symptoms and higher Global Severity Index (1.0 (0.9) versus 0.7 (0.6), p = .039) and Positive Symptom Distress Index (2.0 (0.8) versus 1.7 (0.6), p = .009). Only higher Pittsburgh Sleep Quality Index values predicted higher Global Severity Index ( B = 0.11, p = .041) and Positive Symptom Distress Index ( B = 0.46, p = .007) in suspected OSA participants. Conclusions This study found that individuals with suspected OSA experienced more severe psychiatric symptoms than NCs and that psychiatric symptoms were more severe in the SS group than in the OSA group. The psychiatric symptoms of suspected OSA patients were associated with subjective sleep quality rather than with the apnea-hypopnea index.
    Type of Medium: Online Resource
    ISSN: 1534-7796 , 0033-3174
    RVK:
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2018
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  • 10
    Online Resource
    Online Resource
    Ovid Technologies (Wolters Kluwer Health) ; 2017
    In:  Medicine Vol. 96, No. 21 ( 2017-05), p. e7020-
    In: Medicine, Ovid Technologies (Wolters Kluwer Health), Vol. 96, No. 21 ( 2017-05), p. e7020-
    Type of Medium: Online Resource
    ISSN: 0025-7974
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2017
    detail.hit.zdb_id: 2049818-4
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