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  • Hindawi Limited  (3)
  • English  (3)
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  • Hindawi Limited  (3)
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  • English  (3)
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  • 1
    Online Resource
    Online Resource
    Hindawi Limited ; 2020
    In:  Wireless Communications and Mobile Computing Vol. 2020 ( 2020-09-05), p. 1-10
    In: Wireless Communications and Mobile Computing, Hindawi Limited, Vol. 2020 ( 2020-09-05), p. 1-10
    Abstract: Group activities on social networks are increasing rapidly with the development of mobile devices and IoT terminals, creating a huge demand for group recommendation. However, group recommender systems are facing an important problem of privacy leakage on user’s historical data and preference. Existing solutions always pay attention to protect the historical data but ignore the privacy of preference. In this paper, we design a privacy-preserving group recommendation scheme, consisting of a personalized recommendation algorithm and a preference aggregation algorithm. With the carefully introduced local differential privacy (LDP), our personalized recommendation algorithm can protect user’s historical data in each specific group. We also propose an Intra-group transfer Privacy-preserving Preference Aggregation algorithm (IntPPA). IntPPA protects each group member’s personal preference against either the untrusted servers or other users. It could also defend long-term observation attack. We also conduct several experiments to measure the privacy-preserving effect and usability of our scheme with some closely related schemes. Experimental results on two datasets show the utility and privacy of our scheme and further illustrate its advantages.
    Type of Medium: Online Resource
    ISSN: 1530-8669 , 1530-8677
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2020
    detail.hit.zdb_id: 2045240-8
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  • 2
    Online Resource
    Online Resource
    Hindawi Limited ; 2022
    In:  Wireless Communications and Mobile Computing Vol. 2022 ( 2022-4-4), p. 1-6
    In: Wireless Communications and Mobile Computing, Hindawi Limited, Vol. 2022 ( 2022-4-4), p. 1-6
    Abstract: This study is to uncover the possibilities of CCL20 and IL-17A to be potential hallmarks for laryngeal carcinoma. Relative levels of CCL20 and IL-17A in laryngeal carcinoma tissues were detected by quantitative real-time polymerase chain reaction (qRT-PCR). Correlation between CCL20 and IL-17A was analyzed by Pearson correlation test. Receiver operating characteristic (ROC) curves were depicted for assessing diagnostic values of CCL20 and IL-17A in laryngeal carcinoma. In addition, 98 laryngeal carcinoma patients were followed up for 5 years. Their follow-up data were utilized for assessing prognostic values of CCL20 and IL-17A. CCL20 and IL-17A were upregulated in laryngeal carcinoma tissues than those of normal ones. ROC curves identified diagnostic values of CCL20 ( AUC = 0.9719 , cutoff   value = 4.86 , sensitivity = 98.98 % , specificity = 87.76 % ) and IL-17A ( AUC = 0.7965 , cutoff   value = 3.39 , sensitivity = 71.31 % , specificity = 71.52 % ) in laryngeal carcinoma. Worse prognosis was observed in laryngeal carcinoma patients expressing high level of CCL20 or IL-17A. CCL20 and IL-17A are upregulated in laryngeal carcinoma tissues, which are unfavorable factors for the prognosis of laryngeal carcinoma. CCL20 and IL-17A are promising hallmarks of laryngeal carcinoma.
    Type of Medium: Online Resource
    ISSN: 1530-8677 , 1530-8669
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2045240-8
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  • 3
    Online Resource
    Online Resource
    Hindawi Limited ; 2022
    In:  Journal of Oncology Vol. 2022 ( 2022-11-28), p. 1-10
    In: Journal of Oncology, Hindawi Limited, Vol. 2022 ( 2022-11-28), p. 1-10
    Abstract: Background. Limited and controversial evidence is available on the efficacy of surgery for patients with stage I primary parotid gland lymphoma. Thus, we aimed to investigate whether surgery can enhance the prognosis of patients with stage I primary parotid gland lymphoma using large sample data. Methods. From 1998 to 2015, we searched the Surveillance, Epidemiology, and End Results (SEER) program database and extracted information regarding patients with stage I primary parotid gland lymphoma; we classified these patients into surgery and nonsurgery groups. We calculated overall survival (OS) and cancer-specific survival (CSS) using Kaplan–Meier curves and log-rank testing. Propensity score matching (PSM) analysis was also used to further account for confounding variables before comparing the OS and CSS again. We used the COX proportional hazard regression model in both multivariate and univariate analyses. Results. We enrolled 918 patients with stage I primary parotid gland lymphoma, among which 656 (71.5%) patients underwent surgery. Before PSM, the surgery group had better OS (hazard ratio (HR) = 0.673, 95% confidence interval (CI): 0.519–0.873, and p = 0.003 ) and CSS (HR = 0.595, 95% CI: 0.403–0.879, and p = 0.008 ) than the nonsurgery group. After PSM, surgery was still a beneficial factor for OS (HR = 0.569, 95% CI: 0.399–0.810, and p = 0.002 ) and CSS (HR = 0.384, 95% CI: 0.220–0.669, and p = 0.001 ). Furthermore, in univariate and multivariate analyses, total parotidectomy significantly increased OS ( p = 0.001 and p = 0.021 , respectively) and CSS ( p = 0.001 and p = 0.037 , respectively). Conclusions. In summary, the prognosis of patients with stage I primary parotid gland lymphoma can be significantly improved by surgery. Moreover, total parotidectomy was a protective factor for OS and CSS before and after PSM analysis, suggesting that surgery acts as a significant component in multimodal therapy for early primary parotid gland lymphoma.
    Type of Medium: Online Resource
    ISSN: 1687-8469 , 1687-8450
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2461349-6
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