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  • Cambridge University Press (CUP)  (2)
  • English  (2)
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  • Cambridge University Press (CUP)  (2)
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  • English  (2)
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    Online Resource
    Online Resource
    L-Citrulline supplementation attenuates aortic pressure and pressure waves during metaboreflex activation in postmenopausal women
    Cambridge University Press (CUP) ; 2023
    In:  British Journal of Nutrition
    Details
    In: British Journal of Nutrition, Cambridge University Press (CUP)
    Abstract: Postmenopausal women have augmented pressure wave responses to low-intensity isometric handgrip exercise (IHG) due to an overactive metaboreflex (postexercise muscle ischaemia, PEMI), contributing to increased aortic systolic blood pressure (SBP). Menopause-associated endothelial dysfunction via arginine (ARG) and nitric oxide deficiency may contribute to exaggerated exercise SBP responses. L-Citrulline supplementation (CIT) is an ARG precursor that decreases SBP, pulse pressure (PP) and pressure wave responses to cold exposure in older adults. We investigated the effects of CIT on aortic SBP, PP, and pressure of forward (Pf) and backward (Pb) waves during IHG and PEMI in twenty-two postmenopausal women. Participants were randomised to CIT (10 g/d) or placebo (PL) for 4 weeks. Aortic haemodynamics were assessed via applanation tonometry at rest, 2 min of IHG at 30 % of maximal strength, and 3 min of PEMI. Responses were analysed as change (Δ) from rest to IHG and PEMI at 0 and 4 weeks. CIT attenuated ΔSBP (−9 ± 2 v . −1 ± 1 mmHg, P = 0·006), ΔPP (−5 ± 2 v . 0 ± 1 mmHg, P = 0·03), ΔPf (−6 ± 2 v . −1 ± 1 mmHg, P = 0·01) and ΔPb (−3 ± 1 v . 0 ± 1 mmHg, P = 0·02) responses to PEMI v . PL. The ΔPP during PEMI was correlated with ΔPf ( r = 0·743, P 〈 0·001) and ΔPb ( r = 0·724, P 〈 0·001). Citrulline supplementation attenuates the increase in aortic pulsatile load induced by muscle metaboreflex activation via reductions in forward and backward pressure wave amplitudes in postmenopausal women.
    Type of Medium: Online Resource
    ISSN: 0007-1145 , 1475-2662
    URL: Article
    DOI: 10.1017/S000711452300199X
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2016047-1
    SSG: 12
    SSG: 21
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Residential urban food environment profiles and diet outcomes among adults in Brooklyn, New York: a cross-sectional study
    Cambridge University Press (CUP) ; 2023
    In:  Public Health Nutrition Vol. 26, No. 4 ( 2023-04), p. 877-885
    Details
    In: Public Health Nutrition, Cambridge University Press (CUP), Vol. 26, No. 4 ( 2023-04), p. 877-885
    Abstract: To assess the clustering properties of residential urban food environment indicators across neighbourhoods and to determine if clustering profiles are associated with diet outcomes among adults in Brooklyn, New York. Design: Cross-sectional. Setting: Five neighbourhoods in Brooklyn, New York. Participants: Survey data ( n 1493) were collected among adults in Brooklyn, New York between April 2019 and September 2019. Data for food environment indicators (fast-food restaurants, bodegas, supermarkets, farmer’s markets, community kitchens, Supplemental Nutrition Assistance Program application centres, food pantries) were drawn from New York databases. Latent profile analysis (LPA) was used to identify individuals’ food access-related profiles, based on food environments measured by the availability of each outlet within each participant’s 800-m buffer. Profile memberships were associated with dietary outcomes using mixed linear regression. Results: LPA identified four residential urban food environment profiles (with significant high clusters ranging from 17 to 57 across profiles): limited/low food access, ( n 587), bodega-dense ( n 140), food swamp ( n 254) and high food access ( n 512) profiles. Diet outcomes were not statistically different across identified profiles. Only participants in the limited/low food access profile were more likely to consume sugar-sweetened beverages (SSB) than those in the bodega-dense profile (b = 0·44, P 〈 0·05) in adjusted models. Conclusions: Individuals in limited and low food access neighbourhoods are vulnerable to consuming significant amounts of SSB compared with those in bodega-dense communities. Further research is warranted to elucidate strategies to improve fruit and vegetable consumption while reducing SSB intake within residential urban food environments.
    Type of Medium: Online Resource
    ISSN: 1368-9800 , 1475-2727
    URL: Article
    DOI: 10.1017/S1368980022002476
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2016337-X
    SSG: 21
    Location Call Number Limitation Availability
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