In:
Neonatology, S. Karger AG, Vol. 66, No. 4 ( 1994), p. 221-229
Abstract:
The aim of the present article was to study if changes in glucose availability modify the functional activity of the glucose-dependent developing heart. Our data indicate that a decrease in glucose availability increases tension development and action potential duration at early fetal stages. This fact could probably be explained by the enhancement of Ca 〈 sup 〉 2+ 〈 /sup 〉 movements that regulate the number and turnover rate of membrane glucose transporters in muscle cells. The sensitivity to glucose availability decreases postnatally as the heart becomes fatty acid-dependent.
Type of Medium:
Online Resource
ISSN:
1661-7800
,
1661-7819
Language:
English
Publisher:
S. Karger AG
Publication Date:
1994
detail.hit.zdb_id:
2403535-X
SSG:
12
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