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  • SAGE Publications  (14)
  • English  (14)
  • 2015-2019  (14)
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  • English  (14)
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  • 2015-2019  (14)
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  • 1
    Online Resource
    Online Resource
    A calibration method of dual two-dimensional laser range finders for mobile manipulator
    SAGE Publications ; 2019
    In:  International Journal of Advanced Robotic Systems Vol. 16, No. 5 ( 2019-09-01), p. 172988141987678-
    Details
    In: International Journal of Advanced Robotic Systems, SAGE Publications, Vol. 16, No. 5 ( 2019-09-01), p. 172988141987678-
    Abstract: In this article, a method for calibrating the relative position between dual two-dimensional laser range finders is proposed. This relative position is affected by the manufacture or assembling error of mobile platform, and this error could reduce the accuracy of localization. This article focuses on three-degree-of-freedom calibration, that is, one rotational and two translational degrees of freedom. The entire calibration process can be summed up into three steps. The first step is to allow the dual finders to scan one corner at the same time and then extract the parameters of the corner. The second step is to establish a cost function which is established according to the direction vector of the line and the repeatability of the corners. With this function, the genetic algorithm is used to obtain the final calibration result. Moreover, the finder systematic error and the statistical error are also considered into this article. Simulations and experiments are carried out to verify the proposed method.
    Type of Medium: Online Resource
    ISSN: 1729-8814 , 1729-8814
    URL: Article
    DOI: 10.1177/1729881419876783
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2202393-8
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  • 2
    Online Resource
    Online Resource
    Comparison of cytotoxic T lymphocyte responses against pancreatic cancer induced by dendritic cells transfected with total tumor RNA and fusion hybrided with tumor cell
    SAGE Publications ; 2015
    In:  Experimental Biology and Medicine Vol. 240, No. 10 ( 2015-10), p. 1310-1318
    Details
    In: Experimental Biology and Medicine, SAGE Publications, Vol. 240, No. 10 ( 2015-10), p. 1310-1318
    Abstract: Pancreatic cancer (PC) is a deadly human malignancy. Dendritic cell (DC)-based immunotherapy with whole tumor antigens demonstrates potential efficiency in cancer treatment. Tumor RNA and tumor fusion hybrid cells are sources of whole tumor antigens for preparing DC tumor vaccines. However, the efficacy of these sources in eliciting immune responses against PC has not yet to be directly compared. In the present study, patient-derived PC cells and DCs were fused (DC–tumor hybrids) and primary cultured PC cell-derived total RNA was electroporated into autologous DCs (DC–tumor RNA). The antitumor immune responses induced by DC–tumor hybrids and DC–tumor RNA were compared directly. The results showed that both RNA and hybrid methodologies could induce tumor-specific cytotoxic T lymphocyte (CTL) responses, but pulsing DCs with total tumor RNA could induce a higher frequency of activated CTLs and T-helper cells than fusing DCs with autologous tumor cells. In addition, DC–tumor RNA triggered stronger autologous tumor cell lysis than DC–tumor hybrids. It could be concluded that DCs pulsed with whole tumor RNA are superior to those fused with tumor cells in priming anti-PC CTL responses. Electroporation with total tumor RNA may be more suitable for DC-based PC vaccination.
    Type of Medium: Online Resource
    ISSN: 1535-3702 , 1535-3699
    URL: Article
    DOI: 10.1177/1535370215571884
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2020856-X
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  • 3
    Online Resource
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    Intravenous administration of tirofiban versus loading dose of oral clopidogrel for preventing thromboembolism in stent-assisted coiling of intracranial aneurysms
    SAGE Publications ; 2017
    In:  International Journal of Stroke Vol. 12, No. 5 ( 2017-07), p. 553-559
    Details
    In: International Journal of Stroke, SAGE Publications, Vol. 12, No. 5 ( 2017-07), p. 553-559
    Abstract: Thromboembolic complications after stenting of intracranial aneurysms may be affected by antiplatelet administration. Aims This retrospective study aimed to assess the safety of intravenous tirofiban versus loading dose of oral clopidogrel for preventing thromboembolism in stent-assisted coiling of intracranial aneurysms. Methods From January 2006 to December 2013, 281 patients with cerebral aneurysms were treated with stent-coiling using two antiplatelet strategies in comparison: the initial strategy (a loading dose of ≥300 mg clopidogrel followed by dual antiplatelet, clopidogrel group) and the modified strategy (intravenous administration of tirofiban 8 µg/kg over 3 min followed by a maintenance dose of 0.1 µg/kg/min for 24 h, tirofiban group). The end points were rates of perioperative thromboembolic events and intracranial hemorrhages. Results Thromboembolic events were observed more often in the clopidogrel group (13/120 aneurysms, 10.83%) than the tirofiban group (6/178 aneurysms, 3.37%; P = 0.010), with no increase in the rate of intracranial hemorrhages ( P = 0.164). In the ruptured subgroups, thromboembolic events were significantly fewer in the tirofiban subgroup (5/128, 3.91%) compared with the clopidogrel subgroup (7/53, 13.21%; P = 0.043) with no increase in the rate of hemorrhage ( P = 0.360). Conclusions Intravenous administration of tirofiban is safe in intracranial aneurysms treated with stent-assisted coiling.
    Type of Medium: Online Resource
    ISSN: 1747-4930 , 1747-4949
    URL: Article
    DOI: 10.1177/1747493016677989
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2211666-7
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  • 4
    Online Resource
    Online Resource
    Adjunctive minocycline for major mental disorders: A systematic review
    SAGE Publications ; 2019
    In:  Journal of Psychopharmacology Vol. 33, No. 10 ( 2019-10), p. 1215-1226
    Details
    In: Journal of Psychopharmacology, SAGE Publications, Vol. 33, No. 10 ( 2019-10), p. 1215-1226
    Abstract: This meta-analysis of randomized controlled trials (RCTs) examined the efficacy and safety of minocycline for three major mental disorders: schizophrenia, bipolar disorder and major depressive disorder (MDD). Methods: A systematic literature search of major electronic databases was conducted. Meta-analysis of clinical efficacy as defined by the respective studies, all-cause discontinuation, adverse drug reactions (ADRs) with standardized mean difference (SMD) and risk ratios (RRs) and their 95% confidence intervals (CI) was conducted using random-effects model. Quality assessment was performed with the Jadad scale and Cochrane risk of bias. Results: Sixteen RCTs ( n=1357) on minocycline (50–300 mg/day) for schizophrenia (13 RCTs, n=1196), bipolar depression (1 RCT, n=49), and MDD (2 RCTs, n=112) were analyzed separately by diagnosis. Twelve RCTs mentioned randomized allocation specifically; the weighted Jadad scores were 4.0. Adjunctive minocycline outperformed placebo in improving total psychopathology [SMD: −0.45 (95%CI: −0.73, −0.16), p=0.002; I 2 =77%], positive [SMD: −0.15 (95%CI: −0.28, −0.02), p=0.02; I 2 =0%], negative [SMD: −0.62 (95%CI: −0.95, −0.28), p=0.0003; I 2 =85%] and general psychopathology scores [SMD: −0.28 (95%CI: −0.53, −0.03), p=0.03; I 2 =59%] in schizophrenia. Minocycline showed no significant effect on depressive and manic symptoms in both bipolar depression and MDD. Minocycline caused significantly less headache ( p=0.02, number-needed-to-harm=14, 95%CI=5–14) than placebo in schizophrenia. All-cause discontinuation and other ADRs were similar between minocycline and placebo in each diagnostic category. Conclusion: In this meta-analysis, adjunctive minocycline appeared to be efficacious and safe for schizophrenia. However, the efficacy of adjunctive minocycline for bipolar depression or MDD could not be demonstrated. Review registration: PROSPERO: CRD42018102483
    Type of Medium: Online Resource
    ISSN: 0269-8811 , 1461-7285
    URL: Article
    DOI: 10.1177/0269881119858286
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2028926-1
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  • 5
    Online Resource
    Online Resource
    Synthesis and properties of novel 9,9-diphenyl xanthene-based poly(aryl ether ketone)s with methyl substituents
    SAGE Publications ; 2016
    In:  High Performance Polymers Vol. 28, No. 4 ( 2016-05), p. 436-444
    Details
    In: High Performance Polymers, SAGE Publications, Vol. 28, No. 4 ( 2016-05), p. 436-444
    Abstract: A new bisphenol, 9,9-bis(4-hydroxy-3-methylphenyl)xanthene, was synthesized via a one-pot, two-step synthetic procedure in good yield and used for polymerization with difluorinated aromatic ketones in tetramethylene sulfone in the presence of anhydrous potassium carbonate to form several aromatic poly(ether ketone)s (PEKs) with 9,9-diphenylxanthene moieties and methyl substituents. The newly synthesized high-molecular-weight PEKs having number-average molecular weights in the range of 20,500–25,600 g mol −1 with the polydispersity index ranging from 1.9 to 2.1 were all amorphous and showed high glass transition temperatures in the range of 194–229.8°C, and the temperatures at the 5% weight loss were in the range of 420–445°C with char yields above 60% at 600°C under nitrogen atmosphere. All new PEKs are soluble in polar aprotic solvents, such as N-methyl-2-pyrrolidone, N, N-dimethylacetamide, chloroform, pyridine, m-cresol, and tetrahydrofuran, and could form transparent, strong, and flexible films with tensile strengths of 66–74 MPa, Young’s moduli of 2.47–2.77 GPa, and elongations at break of 8–14%. In addition, these polymers had high transparency with an ultraviolet–visible absorption cutoff wavelength in the 352–356 nm range and low moisture absorption in the range of 0.41–0.56%.
    Type of Medium: Online Resource
    ISSN: 0954-0083 , 1361-6412
    URL: Article
    DOI: 10.1177/0954008315585014
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 1483713-4
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  • 6
    Online Resource
    Online Resource
    New poly(ether benzoxazole)s containing xanthene cardo groups
    SAGE Publications ; 2016
    In:  High Performance Polymers Vol. 28, No. 3 ( 2016-04), p. 309-314
    Details
    In: High Performance Polymers, SAGE Publications, Vol. 28, No. 3 ( 2016-04), p. 309-314
    Abstract: A series of poly(ether benzoxazole)s (PEBOs) containing xanthene cardo groups were prepared via direct one-step condensation polymerization in poly(phosphoric acid/phosphorus pentoxide solution from 9,9-bis[4-(4-carboxyphenoxy)phenyl]xanthene and various bis( o-aminophenol)s. The resulting PEBOs with inherent viscosities of 0.87–1.08 dL g −1 were amorphous and exhibited glass transition temperatures in the range of 245–320°C. These new PEBOs exhibited improved solubility and could be processable from solution. Additionally, the obtained PEBOs showed excellent thermal stability, and did not show a significant weight loss up to 500°C in air or nitrogen, and the temperatures at 10% weight loss were in the range of 533–590°C in nitrogen and 508–570°C in air, with char yields more than 50% at 800°C in nitrogen. All the PEBOs formed strong and flexible films with tensile strengths of 53–80 MPa, tensile moduli of 2.3–2.6 GPa, and elongations at break of 3.2–3.7%.
    Type of Medium: Online Resource
    ISSN: 0954-0083 , 1361-6412
    URL: Article
    DOI: 10.1177/0954008315579697
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
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  • 7
    Online Resource
    Online Resource
    Relationship between coronary artery calcification and calcium deposition in the myocardium
    SAGE Publications ; 2019
    In:  Journal of International Medical Research Vol. 47, No. 7 ( 2019-07), p. 2910-2920
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 47, No. 7 ( 2019-07), p. 2910-2920
    Abstract: To investigate the relationship between coronary artery calcification and calcium deposition in cardiomyocytes. Methods Patients who underwent valve replacement plus surgical ablation for atrial fibrillation, together with left atrial appendage resection, were included. Coronary artery calcification (CAC) score was evaluated prior to surgery using dual-source computed tomography. Samples of left atrial appendage tissue were collected to analyse the following indicators: calcium deposition, alkaline phosphatase activity, calcium content, protein levels of runt-related transcription factor 2 (Runx2), osteopontin and β-catenin, and mRNA levels of osteopontin, endothelin and ghrelin. Relationships between CAC score and various indicators were analysed by univariate logistic or linear regression. Results Out of tissue from eight patients, CAC score was not correlated with cardiomyocyte calcification (odds ratio [OR] 0.984 and OR 0.983; von Kossa or alizarin red staining, respectively). CAC score showed an inverse linear correlation with Runx2 protein (β = –0.75), but was not correlated with osteopontin (β = –0.52) or β-catenin protein (β = –0.56), mRNA levels of osteopontin, endothelin and ghrelin (β = 0.13, 0.02, and 0.02, respectively), alkaline phosphatase activity (β = 0.56), or calcium content (β = –0.22). Conclusions Coronary artery calcification was not correlated with calcium deposition in cardiomyocytes.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/0300060519848587
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2082422-1
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  • 8
    Online Resource
    Online Resource
    Unpacking the Gender Differences on Mental Health : The Effects of Optimism and Gratitude
    SAGE Publications ; 2017
    In:  Psychological Reports Vol. 120, No. 4 ( 2017-08), p. 639-649
    Details
    In: Psychological Reports, SAGE Publications, Vol. 120, No. 4 ( 2017-08), p. 639-649
    Abstract: Mental health studies show that women are likely to score higher on subjective well-being and higher on depression than men. To verify this, the present study collected a sample of 5648 undergraduates in 55 universities in China. Results showed that women reported higher optimism, gratitude, subjective well-being, and depression than men, and that optimism and gratitude mediated the relationship between gender and mental health (subjective well-being and depression). By its implication, women were more likely to be optimistic and grateful, and as such they tended to experience higher subjective well-being and depression simultaneously. This also implies that gender differences on mental health could also be a dispositional issue as well as a socialization one.
    Type of Medium: Online Resource
    ISSN: 0033-2941 , 1558-691X
    URL: Article
    DOI: 10.1177/0033294117701136
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2066930-6
    SSG: 5,2
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  • 9
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    Wingspan stenting can effectively prevent long-term strokes for patients with severe symptomatic atherosclerotic basilar stenosis
    SAGE Publications ; 2016
    In:  Interventional Neuroradiology Vol. 22, No. 3 ( 2016-06), p. 318-324
    Details
    In: Interventional Neuroradiology, SAGE Publications, Vol. 22, No. 3 ( 2016-06), p. 318-324
    Abstract: To investigate the safety and long-term effect of using the Wingspan stent for severe symptomatic atherosclerotic basilar artery stenosis (≥70%). Materials and methods Between July 2007 and April 2013, we had 91 consecutive patients (age range 41–82 years old) with symptomatic severe basilar stenosis (70–99%) who underwent Wingspan stenting at our center. All patients had stenosis-related temporary ischemic attack or strokes. We analyzed the demographic data, pre- and post-procedural cerebral angiography, technical success rate, peri-procedural complications, and clinical and imaging follow-ups. Results The Wingspan stenting procedure was successful in all patients: The stenosis was reduced from 82.2% ± 5.8% pre-stenting to 15.9% ± 5.7% post-stenting. The 30-day peri-operative rate for stroke or death was 14.3%, which included ischemic stroke in 12 cases (12/91 = 13.2%) and subarachnoid hemorrhage in one case (1/91 = 1.1%), with a fatal or disabling stroke rate of 2.2%. Among the 77 patients with clinical follow-up assessment within 7–60 months (mean 31.3 ± 15.1 months) after stenting, four patients (5.2%) had posterior ischemia, including one patient with disabling ischemic stroke (1.3%) and three patients (3.9%) with temporary ischemic attack. The 2-year cumulative stroke rate was 16% (95% CI: 8.2–23.8%). Among 46 patients with imaging assessments at 3–45 months (mean, 9.5 ± 8.3) post-stenting, six (13.0%) patients had restenosis, including two (2/46 = 4.3%) with symptomatic restenosis. Conclusions The benefit of stenting for patients with severe basilar artery stenosis ( 〉 70%) may lie in lowering the long-term fatal and disabling stroke rate; and as long as the peri-operative stroke rate can be kept at a relatively lower level, patients with severe basilar stenosis can benefit from basilar artery stenting.
    Type of Medium: Online Resource
    ISSN: 1591-0199 , 2385-2011
    URL: Article
    DOI: 10.1177/1591019915623797
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2571161-1
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  • 10
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    Long Noncoding RNA PVT1 Promotes EMT and Cell Proliferation and Migration Through Downregulating p21 in Pancreatic Cancer Cells
    SAGE Publications ; 2017
    In:  Technology in Cancer Research & Treatment Vol. 16, No. 6 ( 2017-12), p. 819-827
    Details
    In: Technology in Cancer Research & Treatment, SAGE Publications, Vol. 16, No. 6 ( 2017-12), p. 819-827
    Type of Medium: Online Resource
    ISSN: 1533-0346 , 1533-0338
    URL: Article
    DOI: 10.1177/1533034617700559
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2146365-7
    detail.hit.zdb_id: 2220436-2
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