In:
Advanced Functional Materials, Wiley, Vol. 19, No. 2 ( 2009-01-23), p. 223-234
Abstract:
A highly ordered 2D‐hexagonal mesoporous silica material is functionalized with 3‐aminopropyltriethoxysilane. This organically modified mesoporous material is grafted with a dialdehyde fluorescent chromophore, 4‐methyl‐2,6‐diformyl phenol. Powder X‐ray diffraction, transmission electron microscopy, N 2 sorption, Fourier transform infrared spectroscopy, and UV‐visible absorption and emission have been employed to characterize the material. This material shows excellent selective Zn 2+ sensing, which is due to the fluorophore moiety present at its surface. Fluorescence measurements reveal that the emission intensity of the Zn 2+ ‐bound mesoporous material increases significantly upon addition of various concentrations of Zn 2+ , while the introduction of other biologically relevant (Ca 2+ , Mg 2+ , Na + , and K + ) and environmentally hazardous transition‐metal ions results in either unchanged or weakened intensity. The enhancement of fluorescence is attributed to the strong covalent binding of Zn 2+ , evident from the large binding constant value (0.87 × 10 4 M −1 ). Thus, this functionalized mesoporous material grafted with the fluorescent chromophore could monitor or recognize Zn 2+ from a mixture of ions that contains Zn 2+ even in trace amounts and can be considered as a selective fluorescent probe. We have examined the application of this mesoporous zinc(II) sensor to cultured living cells (A375 human melanoma and human cervical cancer cell, HeLa) by fluorescence microscopy.
Type of Medium:
Online Resource
ISSN:
1616-301X
,
1616-3028
DOI:
10.1002/adfm.200800888
Language:
English
Publisher:
Wiley
Publication Date:
2009
detail.hit.zdb_id:
2029061-5
detail.hit.zdb_id:
2039420-2
SSG:
11
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