GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Wiley  (81)
  • Sun, Kai  (81)
  • English  (81)
Material
Publisher
  • Wiley  (81)
Person/Organisation
Language
  • English  (81)
Years
FID
Subjects(RVK)
  • 1
    Online Resource
    Online Resource
    Automated detection of hippocampal sclerosis using clinically empirical and radiomics features
    Wiley ; 2019
    In:  Epilepsia Vol. 60, No. 12 ( 2019-12), p. 2519-2529
    Details
    In: Epilepsia, Wiley, Vol. 60, No. 12 ( 2019-12), p. 2519-2529
    Abstract: Temporal lobe epilepsy is a common form of epilepsy that might be amenable to surgery. However, magnetic resonance imaging (MRI)‐negative hippocampal sclerosis (HS) can hamper early diagnosis and surgical intervention for patients in clinical practice, resulting in disease progression. Our aim was to automatically detect and evaluate the structural alterations of HS. Methods Eighty patients with pharmacoresistant epilepsy and histologically proven HS and 80 healthy controls were included in the study. Two automated classifiers relying on clinically empirical and radiomics features were developed to detect HS. Cross‐validation was implemented on all participants, and specificity was assessed in the 80 controls. The performance, robustness, and clinical utility of the model were also evaluated. Structural analysis was performed to investigate the morphological abnormalities of HS. Results The computational model based on clinical empirical features showed excellent performance, with an area under the curve (AUC) of 0.981 in the primary cohort and 0.993 in the validation cohort. One of the features, gray‐white matter boundary blurring in the temporal pole, exhibited the highest weight in model performance. Another model based on radiomics features also showed satisfactory performance, with AUC of 0.997 in the primary cohort and 0.978 in the validation cohort. In particular, the model improved the detection rate of MRI‐negative HS to 96.0%. The novel feature of cortical folding complexity of the temporal pole not only played a crucial role in the classifier but also had significant correlation with disease duration. Significance Machine learning with quantitative clinical and radiomics features is shown to improve HS detection. HS‐related structural alterations were similar in the MRI‐positive and MRI‐negative HS patient groups, indicating that misdiagnosis originates mainly from empirical interpretation. The cortical folding complexity of the temporal pole is a potentially valuable feature for exploring the nature of HS.
    Type of Medium: Online Resource
    ISSN: 0013-9580 , 1528-1167
    URL: Issue
    URL: Article
    DOI: 10.1111/epi.v60.12
    DOI: 10.1111/epi.16392
    RVK:
    XA 10000
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2002194-X
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Recurrence and malignant transformation of laryngeal leukoplakia treated with CO 2 laser: A systematic review and meta‐analysis
    Wiley ; 2024
    In:  Clinical Otolaryngology Vol. 49, No. 4 ( 2024-07), p. 404-416
    Details
    In: Clinical Otolaryngology, Wiley, Vol. 49, No. 4 ( 2024-07), p. 404-416
    Abstract: Laryngeal leukoplakia (LL) is a white lesion with high potential of recurrence and malignant transformation. Currently, CO 2 laser has become the primary surgical treatment for LL, and the recurrence and malignant transformation rates after treatment vary widely. Objective We performed a systematic review and meta‐analysis dedicated to evaluating the rates of recurrence and malignant transformation of LL lesions treated with CO 2 laser and exploring relevant risk factors for recurrence or malignant transformation. Methods Literature searches were conducted on ProQuest, PubMed, Web of Science, Ovid Medline, Embase, and Cochrane databases. Some articles identified through hand searching were included. Results A total of 14 articles and 1462 patients were included in this review. Pooled results showed that the overall recurrence rate was 15%, and the malignant transformation rate was 3%. Subgroup analysis showed that the dysplasia grade was not a significant risk factor for the recurrence and malignant transformation of LL ( P 〉 .05). Conclusions The results of this systematic review and meta‐analysis suggest that the CO 2 laser is a safe and effective surgical instrument for the excision of LL, which yields low rates of recurrence and malignant transformation. The risk factors relevant to recurrence or malignant transformation remain unclear and require further investigation.
    Type of Medium: Online Resource
    ISSN: 1749-4478 , 1749-4486
    URL: Issue
    URL: Article
    DOI: 10.1111/coa.v49.4
    DOI: 10.1111/coa.14151
    Language: English
    Publisher: Wiley
    Publication Date: 2024
    detail.hit.zdb_id: 2206071-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Effects of part and whole straw returning on soil carbon sequestration in C3–C4 rotation cropland
    Wiley ; 2019
    In:  Journal of Plant Nutrition and Soil Science Vol. 182, No. 3 ( 2019-06), p. 429-440
    Details
    In: Journal of Plant Nutrition and Soil Science, Wiley, Vol. 182, No. 3 ( 2019-06), p. 429-440
    Abstract: Long‐term no‐tillage management and crop residue amendments to soil were identified as an effective measure to increase soil organic carbon (SOC). The SOC content, SOC stock (SOCs), soil carbon sequestration rate (CSR), and carbon pool management index (CPMI) were measured. A stable isotopic approach was used to evaluate the contributions of wheat and maize residues to SOC at a long‐term experimental site. We hypothesized that under no‐tillage conditions, straw retention quantity would affect soil carbon sequestration differently in surface and deep soil, and the contribution of C3 and C4 crops to soil carbon sequestration would be different. This study involved four maize straw returning treatments, which included no maize straw returning (NT‐0), 0.5 m (from the soil surface) maize straw returning (NT‐0.5), 1 m maize straw returning (NT‐1), and whole maize straw returning (NT‐W). The results showed that in the 0–20 cm soil layer, the SOC content, SOCs, CSR and CPMI of the NT‐W were highest after 14 years of no‐tillage management, and there were obvious differences among the four treatments. However, the SOC, SOCs, and CSR of the NT‐0.5 and NT‐W were the highest and lowest in 20–100 cm, respectively. The value of δ 13 C showed an obviously vertical variability that ranged from –22.01‰ (NT‐1) in the 0–20 cm layer to –18.27‰ (NT‐0.5) in the 60–80 cm layer, with enriched δ 13 C in the 60–80 cm (NT‐0.5 and NT‐1) and 80–100 cm (NT‐0 and NT‐W) layers. The contributions of the wheat and maize‐derived SOC of the NT‐0.5, NT‐1 and NT‐W increased by 11.4, 29.5 and 56.3% and by 10.7, 15.1 and 40.1%, relative to those in the NT‐0 treatment in the 0–20 cm soil layer, respectively. In conclusion, there was no apparent difference in total SOC sequestration between the NT‐0.5, NT‐1, and NT‐W treatments in the 0–100 cm soil layer. The contribution of wheat‐derived SOC was higher than that of maize‐derived SOC.
    Type of Medium: Online Resource
    ISSN: 1436-8730 , 1522-2624
    URL: Issue
    URL: Article
    DOI: 10.1002/jpln.v182.3
    DOI: 10.1002/jpln.201800573
    RVK:
    RA 5430
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 1481142-X
    detail.hit.zdb_id: 1470765-2
    detail.hit.zdb_id: 200063-5
    SSG: 12
    SSG: 13
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Traditional Chinese medicine for frozen shoulder: An evidence‐based guideline
    Wiley ; 2023
    In:  Journal of Evidence-Based Medicine Vol. 16, No. 2 ( 2023-06), p. 246-258
    Details
    In: Journal of Evidence-Based Medicine, Wiley, Vol. 16, No. 2 ( 2023-06), p. 246-258
    Abstract: Frozen shoulder is a common disorder that can lead to long‐lasting impairment in shoulder‐related daily activities. Traditional Chinese medicine (TCM) has played an important role in the effort to manage frozen shoulder. Purpose We aimed to develop an evidence‐based guideline for treating frozen shoulder with traditional Chinese medicine. Study design Evidence‐based guideline. Methods We developed this guideline based on internationally recognized and accepted guideline standards. The guideline development group used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to rate the certainty of evidence and the strength of recommendations. The benefits and harms, resources, accessibility, and other factors were fully taken into account, and the GRADE grid method was used to reach consensus on all recommendations. Results We established a multidisciplinary guideline development panel. Based on a systematic literature search and a face‐to‐face meeting, nine clinical questions were identified. Finally, twelve recommendations were reached by consensus, comprehensively considering the balance of benefits and harms, certainty of evidence, costs, clinical feasibility, accessibility, and clinical acceptability. Conclusion This guideline panel made twelve recommendations, which covered the use of manual therapy, acupuncture, needle knife, Cheezheng Xiaotong plaster, Gutong plaster, exercise therapy and integrated TCM and Western medicine, such as combined modalities and corticosteroid injections. Most of them were weakly recommended or consensus based. The users of this guideline are most likely to be clinicians and health administrators.
    Type of Medium: Online Resource
    ISSN: 1756-5383 , 1756-5391
    URL: Issue
    URL: Article
    DOI: 10.1111/jebm.v16.2
    DOI: 10.1111/jebm.12530
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2474496-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Effect of remote ischemic preconditioning on left atrial remodeling and prothrombotic response after radiofrequency catheter ablation for atrial fibrillation
    Wiley ; 2018
    In:  Pacing and Clinical Electrophysiology Vol. 41, No. 3 ( 2018-03), p. 246-254
    Details
    In: Pacing and Clinical Electrophysiology, Wiley, Vol. 41, No. 3 ( 2018-03), p. 246-254
    Abstract: Radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) is known to induce left atrial remodeling and prothrombotic response. Aims This study aimed to evaluate the effect of remote ischemic preconditioning (RIPC) on left atrial remodeling and prothrombotic response induced by RFCA of AF. Methods Forty‐four patients with drug‐refractory paroxysmal AF undergoing RFCA were randomized into RIPC (four short episodes of forearm ischemia) and control groups before the procedure. Blood samples were collected before RIPC/sham RIPC, and 24 and 72 hours later after the procedure. The atrial remodeling marker matrix metalloproteinase‐9 (MMP‐9) and endothelial damage marker von Willebrand factor (vWF) were measured using enzyme‐linked immunosorbent assay. Platelet activation was evaluated by flow cytometric measurements of the expression of platelet P‐selectin (CD62P) and active glycoprotein IIb/IIIa receptor (PAC‐1). The early recurrence of atrial fibrillation (ERAF) in the two groups was observed over the subsequent 3 months. Results RFCA resulted in a significant increase in MMP‐9 and vWF in both the groups, which persisted for 72 hours. However, the expression of CD62P and PAC‐1 showed less increase during RFCA in either group. The RIPC group showed a lower increase in MMP‐9 and vWF compared with the control group. In contrast, no significant differences were found in the trend of expression of CD62P and PAC‐1 during RFCA between the two groups. The AF recurrence in the 3 months after the ablation was significantly lower in the RIPC group than in the control group. Conclusions RIPC before RFCA for paroxysmal AF significantly reduces the increase in markers of left atrial remodeling and endothelial damage associated with the procedure, and results in a lower ERAF.
    Type of Medium: Online Resource
    ISSN: 0147-8389 , 1540-8159
    URL: Issue
    URL: Article
    DOI: 10.1111/pace.2018.41.issue-3
    DOI: 10.1111/pace.13271
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2037547-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    ChemInform Abstract: Regioselective, Molecular Iodine-Mediated C3 Iodination of Quinolines.
    Wiley ; 2016
    In:  ChemInform Vol. 47, No. 5 ( 2016-01), p. no-no
    Details
    In: ChemInform, Wiley, Vol. 47, No. 5 ( 2016-01), p. no-no
    Type of Medium: Online Resource
    ISSN: 0931-7597
    URL: Issue
    URL: Article
    DOI: 10.1002/chin.v47.5
    DOI: 10.1002/chin.201605170
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2110203-X
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Functional study of novel PAX9 variants: The paired domain and non‐syndromic oligodontia
    Wiley ; 2021
    In:  Oral Diseases Vol. 27, No. 6 ( 2021-09), p. 1468-1477
    Details
    In: Oral Diseases, Wiley, Vol. 27, No. 6 ( 2021-09), p. 1468-1477
    Abstract: To investigate pathogenic variants of the paired box 9 ( PAX9 ) gene in patients with non‐syndromic oligodontia, and the functional impact of these variants. Subjects and Methods Whole exome sequencing and Sanger sequencing were utilized to detect gene variants in a cohort of 80 patients diagnosed with non‐syndromic oligodontia. Bioinformatic and conformational analyses, fluorescence microscopy and luciferase reporter assay were employed to explore the functional impact. Results We identified three novel variants in the PAX9 , including two frameshift variants (c.211_212insA; p.I71Nfs*246 and c.236_237insAC; p.T80Lfs*6 ) , and one missense variant (c.229C  〉  G; p.R77G). Familial co‐segregation verified an autosomal‐dominant inheritance pattern. Conformational analyses revealed that the variants resided in the paired domain, and could cause corresponding structural impairment of the PAX9 protein. Fluorescence microscopy showed abnormal subcellular localizations of frameshift variants, and luciferase assay showed impaired downstream transactivation activities of the bone morphogenetic protein 4 ( BMP4 ) gene in all variants. Conclusions Our findings broaden the spectrum of PAX9 variants in patients with non‐syndromic oligodontia and support that paired domain structural impairment and the dominant‐negative effect are likely the underlying mechanisms of PAX9 ‐related non‐syndromic oligodontia. Our findings will facilitate genetic diagnosis and counselling, and help lay the foundation for precise oral health therapies.
    Type of Medium: Online Resource
    ISSN: 1354-523X , 1601-0825
    URL: Issue
    URL: Article
    DOI: 10.1111/odi.v27.6
    DOI: 10.1111/odi.13684
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2008428-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Tandem Catalysis Inside Double–shelled Nanocages with Separated and Tunable Atomic Catalyst Sites for High Performance Lithium–sulfur Batteries
    Wiley ; 2023
    In:  Advanced Materials
    Details
    In: Advanced Materials, Wiley
    Abstract: Single‐atomic catalysts (SACs) are effective in mitigating the shuttling effect and slow redox kinetics of lithium polysulfides (LiPSs) in lithium–sulfur (Li–S) batteries, but their ideal performance has yet to be achieved due to the multi–step conversion of LiPSs requiring multifunctional active sites for tandem catalysis. Here we have developed double–shelled nano‐cages (DSNCs) to address this challenge, featuring separated and tunable single‐atom sites as nano reactors that trigger tandem catalysis and promote the efficient electrochemical conversion of LiPSs. This enables high capacity and durable Li–S batteries. The DSNCs, with inner Co–N 4 and outer Zn–N 4 sites (S/CoNC@ZnNC DSNCs), exhibit a high specific capacity of 1186 mAh g −1 at 1 C, along with a low capacity fading rate of 0.063% per cycle over 500 cycles. Even with a high sulfur loading (4.2 mg cm −2 ) and a low E/S ratio (6 μL mg −1 ), the cell displays excellent cycling stability. Moreover, the Li–S pouch cells are capable of stable cycling for more than 160 cycles. These results demonstrate the feasibility of driving successive sulfur conversion reactions with separated active sites, and are expected to inspire further catalyst design for high performance Li−S batteries. This article is protected by copyright. All rights reserved
    Type of Medium: Online Resource
    ISSN: 0935-9648 , 1521-4095
    URL: Article
    DOI: 10.1002/adma.202310547
    RVK:
    UA 1538
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1474949-X
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Extramedullary infiltration in pediatric acute myeloid leukemia: Results from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) initiative
    Wiley ; 2024
    In:  Pediatric Blood & Cancer
    Details
    In: Pediatric Blood & Cancer, Wiley
    Abstract: The outcome of extramedullary infiltration (EMI) in pediatric acute myeloid leukemia (AML) is controversial, and little is known about the implications of stem cell transplantation (SCT) and gemtuzumab ozogamicin (GO) treatment on patients with EMI. Methods We retrieved the clinical data of 713 pediatric patients with AML from the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) dataset, and analyzed the clinical and prognostic characteristics of patients with EMI at diagnosis and relapse. Results A total of 123 patients were identified to have EMI at diagnosis and 64 presented with EMI at relapse. The presence of EMI was associated with age ≤2 years, M5 morphology, abnormal karyotype, and KMT2A rearrangements. Hyperleukocytosis and complex karyotype were more prevalent in patients with EMI at relapse. Additionally, patients with EMI at diagnosis had a reduced incidence of FLT3 ITD − /NPM1 + , whereas those with EMI at relapse displayed a lower frequency of FLT3 ITD + . Patients with EMI at diagnosis exhibited a lower complete remission (CR) rate at the end of Induction Course 1 and higher relapse incidence. Importantly, EMI at diagnosis independently predicted both shorter event‐free survival (EFS) and overall survival (OS). Regarding relapse patients, the occurrence of EMI at relapse showed no impact on OS. However, relapse patients with myeloid sarcoma (MS)/no central nervous system (CNS) exhibited poorer OS compared to those with CNS/no MS. Furthermore, regarding patients with EMI at diagnosis, SCT failed to improve the survival, whereas GO treatment potentially enhanced OS. Conclusion EMI at diagnosis is an independent adverse prognostic risk factor for pediatric AML, and GO treatment potentially improves survival for patients with EMI at diagnosis.
    Type of Medium: Online Resource
    ISSN: 1545-5009 , 1545-5017
    URL: Article
    DOI: 10.1002/pbc.31014
    Language: English
    Publisher: Wiley
    Publication Date: 2024
    detail.hit.zdb_id: 2130978-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Protective effect of Cardiotonic Pills on ischemia‐reperfusion induced microcirculatory disturbance and myocardial damage in rats
    Wiley ; 2010
    In:  The FASEB Journal Vol. 24, No. S1 ( 2010-04)
    Details
    In: The FASEB Journal, Wiley, Vol. 24, No. S1 ( 2010-04)
    Type of Medium: Online Resource
    ISSN: 0892-6638 , 1530-6860
    URL: Issue
    URL: Article
    DOI: 10.1096/fsb2.v24.S1
    DOI: 10.1096/fasebj.24.1_supplement.1029.5
    Language: English
    Publisher: Wiley
    Publication Date: 2010
    detail.hit.zdb_id: 1468876-1
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...