In:
British Journal of Haematology, Wiley, Vol. 94, No. 1 ( 1996-07), p. 120-122
Abstract:
We report a patient with chronic myeloid leukaemia who underwent allogeneic marrow transplantation (BMT) but had a molecular relapse 5 months and haematological relapse 15 months after BMT. Since therapy with α‐interferon had been ineffective he received leucocyte infusions from his sibling donor. He developed acute graft‐versus‐host disease and became aplastic 6 weeks later. Despite donor marrow infusion and cytokine stimulation marrow aplasia persisted for 13 weeks. Then, donors' peripheral blood stem cells were given after conditioning with cyclophosphamide and antithymocyte globulin resulting in trilineage engraftment of donor haemopoiesis. Since then, the patient has been in continuous molecular remission for 11 months.
Type of Medium:
Online Resource
ISSN:
0007-1048
,
1365-2141
DOI:
10.1046/j.1365-2141.1996.d01-1770.x
Language:
English
Publisher:
Wiley
Publication Date:
1996
detail.hit.zdb_id:
1475751-5
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