In:
Zeitschrift für anorganische und allgemeine Chemie, Wiley, Vol. 639, No. 8-9 ( 2013-07), p. 1648-1654
Abstract:
Organometallic rhodium complexes have been reported to exhibit promising anticancer activity and some examples have been investigated more extensively over the last years. Based on recent successes of cytotoxic rhodium compounds, this work describes the synthesis and characterization of organorhodium(III) complexes with 3‐hydroxyflavones as bidentate ligands and η 5 ‐coordinated pentamethylcyclopentadienyl (Cp*). The organorhodium compounds were synthesized and characterized by means of NMR spectroscopy and single crystals of the compounds were characterized by X‐ray diffraction analysis. Interestingly, the rhodium complexes were isolated with methanol or triflate coordinated to the central rhodium atom, yielding positively‐charged and neutral complexes, respectively. However, none of the complexes prepared were sufficiently soluble in aqueous media to allow testing their cytotoxicity.
Type of Medium:
Online Resource
ISSN:
0044-2313
,
1521-3749
DOI:
10.1002/zaac.v639.8/9
DOI:
10.1002/zaac.201300145
Language:
English
Publisher:
Wiley
Publication Date:
2013
detail.hit.zdb_id:
201094-X
detail.hit.zdb_id:
1481139-X
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