In:
Scientific Reports, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2022-10-04)
Abstract:
Little is known about the myopic characteristics of lamina cribrosa (LC) curvature. As such, we investigated nasal and temporal LC curvatures in myopia. In this retrospective, cross-sectional study, 144 myopic eyes (refraction 〈 − 2 D ) and 88 non-myopic eyes (refraction 〉 − 0.5 D ) underwent swept-source optical coherence tomography scanning of the LC. The anterior border of LC curvature was delineated with 17 points and interpolated with the “cardinal spline” curve-fitting method. The average curvature indices of the temporal and nasal sides were presented as the temporal and nasal curvatures. Myopic eyes had a mean refraction of − 6.7 ± 2.8 D , while for non-myopic eyes, the value was 0.3 ± 1.0 D . Nasal LC curvature was visible in 54 myopia (37.5%) and 42 non-myopia (47.7%) cases ( P = 0.126), and temporal LC curvature was visible in 142 myopia (98.6%) and 68 non-myopia (77.3%) cases ( P = 0.001). The nasal LC curvature was significantly larger in myopia than in non-myopia ( P 〈 0.001). Contrastingly, the temporal LC curvature was significantly smaller in myopia than in non-myopia ( P 〈 0.001). Axial length was associated with larger nasal LC curvature, smaller temporal LC curvature, and larger nasal–temporal LC curvature difference (all P ’s 〈 0.05). In myopic relative to non-myopic eyes, LC curvature was decreased temporally and increased nasally.
Type of Medium:
Online Resource
ISSN:
2045-2322
DOI:
10.1038/s41598-022-20372-8
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2022
detail.hit.zdb_id:
2615211-3
Permalink