In:
Synthesis, Georg Thieme Verlag KG, Vol. 53, No. 13 ( 2021-07), p. 2277-2285
Kurzfassung:
A novel and highly efficient dehydrogenative cross-coupling reaction between α-amino carbonyl compounds and azoles by copper catalysis using di-tert-butyl peroxide (DTBP) as an oxidant is described. A diverse range of azoles undergo the dehydrogenative imidoylation smoothly with various α-amino carbonyl compounds for the exclusive formation of the corresponding N-imidoyl azoles in high yields under air. The synthetic method has the advantages of good functional-group tolerance, wide substrate scope, excellent yields, and simple operation, thus providing a convenient and practical protocol for the synthesis of functionalized azoles.
Materialart:
Online-Ressource
ISSN:
0039-7881
,
1437-210X
Sprache:
Deutsch
Verlag:
Georg Thieme Verlag KG
Publikationsdatum:
2021
ZDB Id:
204080-3
ZDB Id:
2033062-5
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