In:
Synthesis, Georg Thieme Verlag KG, Vol. 50, No. 03 ( 2018-02), p. 583-592
Kurzfassung:
An efficient and simple method for the synthesis of pyrazolo[3,4-a]acridine and pyrazolo[4,3-a] acridine derivatives directly form nitro compounds by in situ reduction and cyclization reaction under Fe/H2O medium is reported. Compared to amino compounds, nitro compounds are more stable and easier to obtain. In addition, because iron is a nontoxic, inexpensive, and environmentally friendly reductant, this method is especially suitable for organic synthesis. The other advantages of this process are cheap raw materials, less pollution, and wide substrate range.
Materialart:
Online-Ressource
ISSN:
0039-7881
,
1437-210X
DOI:
10.1055/s-0036-1589124
Sprache:
Deutsch
Verlag:
Georg Thieme Verlag KG
Publikationsdatum:
2018
ZDB Id:
204080-3
ZDB Id:
2033062-5
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