GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Causas e tratamento da hipercromia periorbital
    Pontifical Catholic University of Sao Paulo (PUC-SP) ; 2016
    In:  Revista da Faculdade de Ciências Médicas de Sorocaba Vol. 18, No. 3 ( 2016-09), p. 133-139
    Details
    In: Revista da Faculdade de Ciências Médicas de Sorocaba, Pontifical Catholic University of Sao Paulo (PUC-SP), Vol. 18, No. 3 ( 2016-09), p. 133-139
    Type of Medium: Online Resource
    ISSN: 1517-8242 , 1984-4840
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.5327/Z1984-48402016
    DOI: 10.5327/Z1984-4840
    DOI: 10.5327/Z1984-4840201623330
    Language: Unknown
    Publisher: Pontifical Catholic University of Sao Paulo (PUC-SP)
    Publication Date: 2016
    detail.hit.zdb_id: 2552292-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Vectocardiographic analysis of right ventricular electrical conduction delay
    Faculdade de Filosofia e Ciências ; 2022
    In:  Journal of Human Growth and Development Vol. 32, No. 3 ( 2022-10-31), p. 277-283
    Details
    In: Journal of Human Growth and Development, Faculdade de Filosofia e Ciências, Vol. 32, No. 3 ( 2022-10-31), p. 277-283
    Abstract: Introduction: The electrocardiographic interpretation of end conduction delay (ECD) in the right ventricular branch of the heart has already generated some hypotheses that this right branch is not single, as anatomically demonstrated, and can be divided into distinct terminal branches when we analyze tracings through the vectorcardiogram. Methods: There were 227 electrocardiograms selected, with typical characteristics defined as ECD of patients from the electrocardiography service of the Centro Universitário Saúde ABC, of both sexes, in the age range of 18 to 87 years, with varied ethnicities, weight and height, with cardiovascular risk factors or without them. We performed vectorcardiograms in these patients to observe the behavior of the final portion of electrical conduction. Results: Analyzing the vectorcardiographic tracings of patients who presented ECD in electrocardiogram, we confirmed in the recording by the frontal plane, the presence of ECD but recorded in three distinct regions; 103 patients in the right upper quadrant between -120° and -150°, 45 patients in the right lower quadrant between +170° and -170°, and medial, and 79 patients in the right lower quadrant between +110° and + 140°. Conclusion: Electrical depolarization of the heart in the right ventricle in electrocardiographic tracings apparently records typical alterations that we can diagnose as depolarization of a single bundle; but when we performed vectorcardiograms, we recorded three distinct zones of right ventricular depolarization with delay; i.e., three distinct sectors of right ventricle free wall delay, such as type I (upper), type II (lower) and type III (medial).
    Type of Medium: Online Resource
    ISSN: 2175-3598 , 0104-1282
    URL: Issue
    URL: Article
    DOI: 10.36311//
    DOI: 10.36311/jhgd.v32.13778
    Language: Unknown
    Publisher: Faculdade de Filosofia e Ciências
    Publication Date: 2022
    detail.hit.zdb_id: 3072842-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Assessing the Clinical and Epidemiological profile of patients affected by chagas disease in Belem, Pará, from 2015 to 2018
    AI Publications ; 2023
    In:  International Journal of Advanced Engineering Research and Science Vol. 10, No. 9 ( 2023), p. 32-38
    Details
    In: International Journal of Advanced Engineering Research and Science, AI Publications, Vol. 10, No. 9 ( 2023), p. 32-38
    Abstract: Chagas disease is a chronic health condition with high morbidity and mortality. It has an impact on public health and social and economic aspects, and despite efforts and health surveillance measures, outbreaks of the disease still occur. Objective: To evaluate the epidemiological profile of patients affected by Chagas' disease in Belém between 2015 and 2018. Methodology: This is a cross-sectional, retrospective study based on data collected from the notification and disease system, with data collected on cases in the established period, with information such as schooling, age group and gender. Results: There was a higher prevalence of young patients aged between 20 and 59, with a predominance of males and no correct identification of schooling in the notifications. In addition, there was an increase in the number of cases in 2017, but within the expected level of endemicity. Conclusion: Despite the epidemiological transition and the general decrease in the number of cases, Chagas disease is still an important factor to be evaluated by public health, with preventive policies being maintained, as well as public hygiene and basic sanitation situations.
    Type of Medium: Online Resource
    ISSN: 2349-6495 , 2456-1908
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.22161/ijaers.109
    DOI: 10.22161/ijaers
    DOI: 10.22161/ijaers.109.5
    Language: Unknown
    Publisher: AI Publications
    Publication Date: 2023
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Brugada syndrome: current concepts and genetic background
    Faculdade de Filosofia e Ciências ; 2021
    In:  Journal of Human Growth and Development Vol. 31, No. 1 ( 2021-04-28), p. 152-176
    Details
    In: Journal of Human Growth and Development, Faculdade de Filosofia e Ciências, Vol. 31, No. 1 ( 2021-04-28), p. 152-176
    Abstract: Brugada syndrome (BrS) is a hereditary clinical-electrocardiographic arrhythmic entity with low worldwide prevalence. The syndrome is caused by changes in the structure and function of certain cardiac ion channels and reduced expression of Connexin 43 (Cx43) in the Right Ventricle (RV), predominantly in the Right Ventricular Outflow Tract (VSVD), causing electromechanical abnormalities. The diagnosis is based on the presence of spontaneous or medicated ST elevation, characterized by boost of the J point and the ST segment ≥2 mm, of superior convexity "hollow type" (subtype 1A) or descending rectilinear model (subtype 1B). BrS is associated with an increased risk of syncope, palpitations, chest pain, convulsions, difficulty in breathing (nocturnal agonal breathing) and/or Sudden Cardiac Death (SCD) secondary to PVT/VF, unexplained cardiac arrest or documented PVT/VF or Paroxysmal atrial fibrillation (AF) in the absence of apparent macroscopic or structural heart disease, electrolyte disturbance, use of certain medications or coronary heart disease and fever. In less than three decades since the discovery of Brugada syndrome, the concept of Mendelian heredity has come undone. The enormous variants and mutations found mean that we are still far from being able to concretely clarify a genotype-phenotype relationship. There is no doubt that the entity is oligogenetic, associated with environmental factors, and that there are variants of uncertain significance, especially the rare variants of the SCN5A mutation, with European or Japanese ancestors, as well as a spontaneous type 1 or induced pattern, thanks to gnomAD (coalition) researchers who seek to aggregate and harmonize exome and genome sequencing data from a variety of large scale sequencing projects and make summary data available to the scientific community at large). Thus, we believe that this in depth analytical study of the countless mutations attributed to BrS may constitute a real cornerstone that will help to better understand this intriguing syndrome.
    Type of Medium: Online Resource
    ISSN: 2175-3598 , 0104-1282
    URL: Issue
    URL: Article
    DOI: 10.36311//
    DOI: 10.36311/jhgd.v31.11074
    Language: Unknown
    Publisher: Faculdade de Filosofia e Ciências
    Publication Date: 2021
    detail.hit.zdb_id: 3072842-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    The effects of aerobic exercise on biochemical parameters in individuals with CKD on hemodialysis: A longitudinal study
    Faculdade de Filosofia e Ciências ; 2020
    In:  Journal of Human Growth and Development Vol. 30, No. 2 ( 2020-06-17), p. 251-259
    Details
    In: Journal of Human Growth and Development, Faculdade de Filosofia e Ciências, Vol. 30, No. 2 ( 2020-06-17), p. 251-259
    Abstract: Background: Chronic kidney disease is directly related to cardiovascular disorders. Guided physical exercises significantly improve the adverse effects of dialytic treatment. Objective: To analyze changes in biochemical parameters of subjects with chronic kidney disease undergoing moderate exercise during hemodialysis. Methods: This is an experimental study composed of 54 subjects submitted to hemodialysis, split into a control group and a group with intervention. The experimental group underwent three weekly sessions of aerobic exercise, performed during hemodialysis sessions, with a duration of 30 minutes, for 12 weeks. The blood parameters of both groups were compared. Results: Statistically significant differences were observed between pre (p=0.001) and post-exercise protocol for urea (p=0.006), calcium (p=0.001), alanine aminotransferase (p=0.020) and sodium (p= 〈 0.001). In the control group, we observed significant differences for the calcium variable (p 〈 0.001), alanine aminotransferase (p=0.024), hematocrit (p=0.015), calcium vs phosphorus (p=0.018), and sodium (p=0.023), before and after the period. Conclusion: Aerobic training during hemodialysis was able to maintain blood level stability in patients with chronic kidney disease, both during and at the end of the protocol, even considering increased blood flow. This trial is registered in the Brazilian registry of clinical Trials - number RBR-7354r6. Registration date: July 5, 2018 at 12:59 PM. Last Update: July 24, 2018 at 10:24 AM. Identification of the test - UTN Number: U1111-1216-8272.
    Type of Medium: Online Resource
    ISSN: 2175-3598 , 0104-1282
    URL: Article
    DOI: 10.7322/jhgd.v30.10374
    Language: Unknown
    Publisher: Faculdade de Filosofia e Ciências
    Publication Date: 2020
    detail.hit.zdb_id: 3072842-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Proyectos Seleccionados / Selected Projects
    Universidad de Navarra ; 2019
    In:  Memoria de Proyectos ( 2019-09-03), p. 7-41
    Details
    In: Memoria de Proyectos, Universidad de Navarra, ( 2019-09-03), p. 7-41
    Type of Medium: Online Resource
    ISSN: 2255-2421
    URL: Article
    DOI: 10.15581/023.5.38243
    Language: Unknown
    Publisher: Universidad de Navarra
    Publication Date: 2019
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Three urgent needs in the battle against COVID-19: specific medications, information and acceptance of Pandemic
    Faculdade de Filosofia e Ciências ; 2021
    In:  Journal of Human Growth and Development Vol. 31, No. 3 ( 2021-12-01), p. 371-375
    Details
    In: Journal of Human Growth and Development, Faculdade de Filosofia e Ciências, Vol. 31, No. 3 ( 2021-12-01), p. 371-375
    Abstract: The first confirmed case of COVID-19 was notified to the Brazilian Ministry of Health on February 26, 2020. On November 20, 2021, by the end of Epidemiological Week-46 (EW-46) 257,168,692 confirmed cases of COVID-19 reported worldwide. Among the countries with the highest number of accumulated cases the United States of America ranks number one (47,701,872), followed by India (34,510,413), Brazil (22,012,150), the United Kingdom (9,857,658), and Russia (9,135,149). Concerning deaths, 5,146,467 were confirmed worldwide until November 20, 2021. The United States was the country with the highest accumulated number of deaths (771,013), followed by Brazil (612,587), India (465,662), Mexico (292,145), and Russia (257,891).
    Type of Medium: Online Resource
    ISSN: 2175-3598 , 0104-1282
    URL: Issue
    URL: Article
    DOI: 10.36311//
    DOI: 10.36311/jhgd.v31.12794
    Language: Unknown
    Publisher: Faculdade de Filosofia e Ciências
    Publication Date: 2021
    detail.hit.zdb_id: 3072842-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Cardiac sodium channel, its mutations and their spectrum of arrhythmia phenotypes
    Faculdade de Filosofia e Ciências ; 2016
    In:  Journal of Human Growth and Development Vol. 26, No. 3 ( 2016-11-28), p. 281-
    Details
    In: Journal of Human Growth and Development, Faculdade de Filosofia e Ciências, Vol. 26, No. 3 ( 2016-11-28), p. 281-
    Abstract: The mechanisms of cellular excitability and propagation of electrical signals in the cardiac muscle are very important functionally and pathologically. The heart is constituted by three types of muscle: atrial, ventricular, and specialized excitatory and conducting fi bers. From a physiological and pathophysiological point of view, the conformational states of the sodium channel during heart function constitute a signifi cant aspect for the diagnosis and treatment of heart diseases. Functional states of the sodium channel (closed, open, and inactivated) and their structure help to understand the cardiac regulation processes. There are areas in the cardiac muscle with anatomical and functional differentiation that present automatism, thus subjecting the rest of the fi bers to their own rhythm. The rate of these (pacemaker) areas could be altered by modifi cations in ions, temperature and especially, the autonomic system. Excitability is a property of the myocardium to react when stimulated. Another electrical property is conductivity, which is characterized by a conduction and activation process, where the action potential, by the all-or-nothing law, travels throughout the heart. Heart relaxation also stands out as an active process, dependent on the energetic output and on specificion and enzymatic actions, with the role of sodium channel being outstanding in the functional process. In the gene mutation aspects that encode the rapid sodium channel (SCN5A gene), this channel is responsible for several phenotypes, such as Brugada syndrome, idiopathic ventricular fibrillation, dilated cardiomyopathy, early repolarization syndrome, familial atrial fibrillation, variant 3 of long QT syndrome, multifocal ectopic ventricular contractions originating in Purkinje arborizations, progressive cardiac conduction defect (Lenègre disease), sudden infant death syndrome, sick sinus syndrome, sudden unexplained nocturnal death syndrome, among other sodium channel alterations with clinical overlapping. Finally, it seems appropriate to consider the “sodium channel syndrome” (mutations in the gene of the α subunit of the sodium channel, SCN5A gene) as a single clinical entity that may manifest in a wide range of phenotypes, to thus have a better insight on these cardiac syndromes and potential outcomes for their clinical treatment.
    Type of Medium: Online Resource
    ISSN: 2175-3598 , 0104-1282
    URL: Article
    DOI: 10.7322/jhgd.122759
    Language: Unknown
    Publisher: Faculdade de Filosofia e Ciências
    Publication Date: 2016
    detail.hit.zdb_id: 3072842-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Fractalidade e comportamento caótico da variabilidade da frequência cardíaca como preditores de hipotensão após raquianestesia: protocolo de ensaio clínico randomizado
    Faculdade de Filosofia e Ciências ; 2019
    In:  Journal of Human Growth and Development Vol. 29, No. 2 ( 2019-11-05), p. 284-294
    Details
    In: Journal of Human Growth and Development, Faculdade de Filosofia e Ciências, Vol. 29, No. 2 ( 2019-11-05), p. 284-294
    Abstract: Introdução: Todas as drogas e técnicas que induzem o estado anestésico atuam de alguma forma no SNA. A administração de anestésicos locais no espaço subaracnóideo produz bloqueio motor, sensitivo e simpático, com latências e níveis de bloqueio variáveis e independentes. O bloqueio motor é o primeiro a ser instalado, seguido pelo simpático e sensitivo. O bloqueio simpático afeta de 2 a 6 dermátomos acima do bloqueio sensitivo. A recuperação da raquianestesia é avaliada através de uma escala definida em 1979 por Bromage e baseia-se exclusivamente no retorno da função motora e não leva em conta a recuperação da atividade da SNA. A persistência do bloqueio simpático pode implicar em maior incidência de retenção urinária, bradicardia e hipotensão. Objetivo: Caracterizar a variabilidade da frequência cardíaca durante anestesia subaracnóidea por meio de métodos lineares no domínio da frequência e métodos não lineares no domínio caos e definir a duração do bloqueio autonômico em raquianestesia através desses parâmetros, bem como identificar índices de variabilidade da frequência cardíaca (VFC) que podem ser usados como preditores de hipotensão perioperatória. Método: Um ensaio clínico randomizado, duplo-cego será realizado em um hospital de grande porte localizado na região sul do Ceará, no Brasil, e no HUJB em Cajazeiras, na Paraíba. Sessenta pacientes do ambulatório de anestesia serão incluídos. Os pacientes serão divididos em dois grupos: um grupo receberá Bupivacaína com clonidina e o outro grupo receberá apenas bupivacaína na dose de 15 mg. A amostra será composta por 60 pacientes ASA I a III, a serem submetidos a cirurgia ortopédica de membros inferiores e abdome inferior sob raquianestesia. A Variabilidade da Frequência Cardíaca será avaliada em três momentos: repouso, antes da anestesia; 20 min após a instalação do bloqueio, e no momento da recuperação da função motora, de acordo com os critérios de Bromage. Será avaliada a incidência de hipotensão perioperatória nos dois grupos. Métodos lineares serão utilizados no domínio da freqüência e não-lineares no domínio do caos: plot de Poincaré, entropia aproximada, Análise de Flutuação Destendenciada (DFA) e Dimensão de Correlação. Os dados serão recolhidos através de um cardiofrequencímetro Polar V800® e devidamente submetidos para análise e filtragem pelo software Kubios 3.0®.  Discussão: Na literatura encontramos dados avaliando a instalação do bloqueio simpático através da VFC utilizando métodos lineares, no entanto, faltam estudos utilizando métodos baseados no domínio do caos. Alguns estudos abordam o valor da VFC como um preditor de hipotensão após a anestesia subaracnóidea, principalmente usando métodos lineares no domínio da frequência. Entende-se ser importante analisar esses fatores utilizando métodos já validados no domínio do caos, complexidade e fractalidade, mais compatíveis com a complexidade do comportamento dos sistemas biológicos, na caracterização da função autonômica durante a anestesia subaracnóidea. Registro: O ensaio clínico foi registrado no Registro Brasileiro de Ensaios Clínicos (ReBEC) sob o número RBR-4Q53D6.
    Type of Medium: Online Resource
    ISSN: 2175-3598 , 0104-1282
    URL: Article
    DOI: 10.7322/jhgd.v29.9433
    Language: Unknown
    Publisher: Faculdade de Filosofia e Ciências
    Publication Date: 2019
    detail.hit.zdb_id: 3072842-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Brugada syndrome unmasked by fever and paradoxical lower degree of dromotropic disturbance in the right ventricular outflow tract
    Faculdade de Filosofia e Ciências ; 2022
    In:  Journal of Human Growth and Development Vol. 32, No. 2 ( 2022-06-23), p. 187-191
    Details
    In: Journal of Human Growth and Development, Faculdade de Filosofia e Ciências, Vol. 32, No. 2 ( 2022-06-23), p. 187-191
    Abstract: Brugada syndrome (BrS) is an inherited clinical-electrocardiographic arrhythmic entity with an autosomal dominant genetic pattern of inheritance or de novo variant. The syndrome has low worldwide prevalence, but is endemic in Southeast Asian countries (Thailand, Philippines and Japan). The BrS is a subtle structural heart disease (SHD), and the diagnosis is only possible when the so-called type 1 Brugada ECG pattern is spontaneously present or induced for example with fever. Repolarization-depolarization disturbances in BrS patients can be caused by genetic mutations, abnormal neural crest cell migration, low expression of connexin-43 gap junction protein, or connexome disturbances. A recent autopsy study revealed increase in biventricular collagen with myocardial fibrosis when compared with control subjects although the main affected cardiac territory is the right ventricular outflow tract (RVOT). In this location, there is abnormally low expression of significant connexin-43 gap junction responsible for the electro-vectorcardiographic manifestations of terminal QRS conduction delay in the right standard precordial leads (V1-V2), high right precordial leads (V1H-V2H), as well as in the unipolar aVR lead (“the forgotten lead”). Based on their location, these leads reflect the electrical activity of the RVOT.
    Type of Medium: Online Resource
    ISSN: 2175-3598 , 0104-1282
    URL: Issue
    URL: Article
    DOI: 10.36311//
    DOI: 10.36311/jhgd.v32.13319
    Language: Unknown
    Publisher: Faculdade de Filosofia e Ciências
    Publication Date: 2022
    detail.hit.zdb_id: 3072842-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...