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  • 1
    Online Resource
    Online Resource
    Frontiers Media SA ; 2024
    In:  Frontiers in Oncology Vol. 14 ( 2024-4-26)
    In: Frontiers in Oncology, Frontiers Media SA, Vol. 14 ( 2024-4-26)
    Abstract: The gut microbiota has been significantly associated with differentiated thyroid cancer (DTC). However, the causal relationship between the gut microbiota and DTC remains unexplored. Methods Genome-wide association study (GWAS) summary databases were utilized to select exposures and outcomes. The Mendelian randomization (MR) method was employed to investigate the causal relationship between the gut microbiota and DTC. A sensitivity analysis was performed to assess the reliability of the findings. Results Four bacterial traits were associated with the risk of DTC: Class Mollicutes [odds ratio (OR) = 10.953, 95% confidence interval (95% CI): 2.333–51.428, p = 0.002], Phylum Tenericutes (OR = 10.953, 95% CI: 2.333–51.428, p = 0.002), Genus Eggerthella (OR = 3.219, 95% CI: 1.033–10.024, p = 0.044), and Order Rhodospirillales (OR = 2.829, 95% CI: 1.096–7.299, p = 0.032). The large 95% CI range for the Class Mollicutes and the Phylum Tenericutes may be attributed to the small sample size. Additionally, four other bacterial traits were negatively associated with DTC: Genus Eubacterium fissicatena group (OR = 0.381, 95% CI: 0.148–0.979, p = 0.045), Genus Lachnospiraceae UCG008 (OR = 0.317, 95% CI: 0.125–0.801, p = 0.015), Genus Christensenellaceae R-7 group (OR = 0.134, 95% CI: 0.020–0.886, p = 0.037), and Genus Escherichia Shigella (OR = 0.170, 95% CI: 0.037–0.769, p = 0.021). Conclusion These findings contribute to our understanding of the pathological mechanisms underlying DTC and provide novel insights for the clinical treatment of DTC.
    Type of Medium: Online Resource
    ISSN: 2234-943X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2024
    detail.hit.zdb_id: 2649216-7
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  • 2
    Online Resource
    Online Resource
    Frontiers Media SA ; 2021
    In:  Frontiers in Psychiatry Vol. 12 ( 2021-5-21)
    In: Frontiers in Psychiatry, Frontiers Media SA, Vol. 12 ( 2021-5-21)
    Abstract: Parents raising children with autism spectrum disorder (ASD) usually carry on their daily life under tremendous stress, but limited empirical research has been devoted to this population. It is known that parents' health status directly impacts therapeutic outcome of ASD children. As an important regulator in cardiovascular, nervous and immune systems, nitric oxide (NO) levels haven't been reported in parents of ASD children yet. In this study, we measured urine nitrite and nitrate from 43 ASD parents (ASD-P), and 43 healthy adults in the same range of age (Control) who didn't have any ASD descendants. Comparison between the ASD-P and Control groups showed that NO 2 - , NO 3 - , and NO 2 - / NO 3 - were all significantly lower in the ASD-P group. Analysis on the interaction effect of sex and group indicated that urine NO 3 - of mothers in ASD-P was lower than that in females of the Control group, but no significant difference was observed between males in both groups. It is for the first time that urine nitric oxide metabolites (nitrite, nitrate) levels were precisely reported to differentiate parents of autistic children from other adults without ASD descendants. This phenomenon suggests that parents (especially mothers) of autistic children might have experienced more mental and physical stressors, which led to decreased NO levels during metabolism. Further investigations are necessary to uncover the etiology of low urine NO among parents of autistic children.
    Type of Medium: Online Resource
    ISSN: 1664-0640
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2564218-2
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  • 3
    Online Resource
    Online Resource
    The Electrochemical Society ; 2022
    In:  Journal of The Electrochemical Society Vol. 169, No. 3 ( 2022-03-01), p. 030512-
    In: Journal of The Electrochemical Society, The Electrochemical Society, Vol. 169, No. 3 ( 2022-03-01), p. 030512-
    Abstract: To tackle the issues of lithium sulfur battery (Li-S), a strategy of simultaneous regulating the band gap and catalytic activity of TiO 2 via embedded MoO 2 based on interlaced carbon nanotubes carrier as substrate material to achieve efficient adsorption has been proposed. This substrate material is controlled to be nanosized with abundant catalytically active sites and widely-distributed pore through the cross-linked porous conductive skeleton, further promoting the electrolyte penetration and charge transfer. In addition, the introduction of MoO 2 tailors the Ti electronic states, so the substrate material renders high adsorption energy of −1.47 eV for Li 2 S 6 by theoretical calculation. Furthermore, the cathode exhibits high conversion efficiency from long-chain lithium polysulfide to Li 2 S (Q low /Q high (the conversion capacity of Li 2 S) is 2.91 at 0.1C) and excellent sulfur utilization and fast sulfur reaction kinetics. The cathode also exhibits a low-capacity fade and excellent cycling performance.
    Type of Medium: Online Resource
    ISSN: 0013-4651 , 1945-7111
    RVK:
    Language: Unknown
    Publisher: The Electrochemical Society
    Publication Date: 2022
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  • 4
    In: Frontiers in Surgery, Frontiers Media SA, Vol. 9 ( 2022-4-26)
    Abstract: This study aimed to compare the short-term clinical efficacy between prior and traditional approach of Henle trunk in laparoscopic right hemicolectomy (LRH) for right colon cancer. A total of 161 patients underwent LRH for right colon cancer between June 2018 and December 2020 by the same group of physicians. The prior approach of Henle trunk (priority group) was used in 82 patients and traditional approach in 79 (traditional group). The demographics and clinicopathological characteristics were recorded and retrospectively analyzed. As compared to the traditional group, the mean blood loss reduced significantly [73.84 ± 17.31 mL vs. 83.42 ± 30.16 mL; P = 0.001], the operation time was markedly shorter [151.35 ± 6.75 min vs. 159.13 ± 18.85 min; P = 0.014], and the intraoperative vascular injury rate was significantly lower [6.1% (5/82). vs. 17.7% (14/79); P = 0.022]. There were no significant differences in the postoperative complications, first exhaust time, first defecation time, drainage time, postoperative hospital stay, quality evaluation of surgical specimens and pathological findings between two groups. Our study shows that the priority management of Henle trunk in the LRH for right colon cancer is a safe and feasible procedure with less blood loss, shorter operation time and lower intraoperative vascular injury rate.
    Type of Medium: Online Resource
    ISSN: 2296-875X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2773823-1
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  • 5
    Online Resource
    Online Resource
    Frontiers Media SA ; 2020
    In:  Frontiers in Oncology Vol. 10 ( 2020-9-25)
    In: Frontiers in Oncology, Frontiers Media SA, Vol. 10 ( 2020-9-25)
    Type of Medium: Online Resource
    ISSN: 2234-943X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2020
    detail.hit.zdb_id: 2649216-7
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  • 6
    In: Materials Research Express, IOP Publishing, Vol. 1, No. 3 ( 2014-06-30), p. 036101-
    Type of Medium: Online Resource
    ISSN: 2053-1591
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2014
    detail.hit.zdb_id: 2760382-9
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