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  • 1
    In: Pamukkale Medical Journal, Pamukkale University, Vol. 10, No. 3 ( 2017), p. 216-220
    Type of Medium: Online Resource
    ISSN: 1309-9833 , 1308-0865
    Language: Unknown
    Publisher: Pamukkale University
    Publication Date: 2017
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  • 2
    Online Resource
    Online Resource
    Pera Publishing ; 2010
    In:  European Journal of Therapeutics Vol. 16, No. 1 ( 2010-01-01), p. 10-14
    In: European Journal of Therapeutics, Pera Publishing, Vol. 16, No. 1 ( 2010-01-01), p. 10-14
    Abstract: Active life and functional capacity in rheumatologic diseases have been affected, health-related quality of life results are accepted as important indicators. Our study was done with the aim of to determine life quality of patients who with rheumatologic problems, and its correlate with some symptoms. Study was done as descriptive with 101 patients (38 ankylosing spondylitis, 34 rheumatoid arthritis, 10 systemic lupus erythematosus, 10 Behcet's disease and 9 osteoarthritis) who were admitted to the rheumatology clinic and want to join study. Datas were collected with a questionnaire that included sociodemographic characteristics, symptoms and frequency of symptoms related questions prepared by researchers and Short Form-36 quality of life. In evaluation of the data's, frequency, chi-square, Kruskall Wallis analysis were done by using SPSS. The age mean of patients were 40.3±1.3 years and mean of duration of illness were 31.7±4.0 months. SF-36 quality of life point mean scores of patients with rheumatologic problems 33.0±1.4 for physical dimension; and 38.9±1.6 for mental dimension;, respectively. Statistically significant relationship wasn't find between quality of life and diagnose of patients (p 〉 0.05). But, the point mean of quality of life were significantly lower in patients who have too much pain, stiffness, swelling in joints, fatigue, motion strain, emotional problems (p 〈 0.05). Rheumatologic diseases cause to difficulties when doing daily life activities of patients and they reduce life quality of patients. When the frequency of symptoms get raised life quality became more worsen.
    Type of Medium: Online Resource
    ISSN: 2564-7040 , 2564-7784
    Language: Unknown
    Publisher: Pera Publishing
    Publication Date: 2010
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  • 3
    Online Resource
    Online Resource
    Anatolian Current Medical Journal ; 2023
    In:  Anatolian Current Medical Journal Vol. 5, No. 1 ( 2023-01-20), p. 18-23
    In: Anatolian Current Medical Journal, Anatolian Current Medical Journal, Vol. 5, No. 1 ( 2023-01-20), p. 18-23
    Abstract: Aim: Alexithymia is a disorder associated with difficulty in recognizing and expressing feelings, which can lead to an increased susceptibility to disease development that makes alexithymia a possible risk factor for chronic kidney disease (CKD). This study was performed to evaluate for alexithymia in pre-dialysis CKD and end-stage renal disease patients undergoing hemodialysis.Material and Method: The study was conducted in the Nephrology Outpatient Department and Hemodialysis unit of Ümraniye Research and Training Hospital. The patients had to have a diagnosis of CKD. Demographic data form, routine biochemical follow up data of patients, Toronto Alexithymia Scale (TAS), and Hospital Depression and Anxiety Scale (HADS) were used in this study. The statistical significance level was determined as p & lt;0.05.Results: A total of 111 patients (mean age 58.10±13.48 years, 61% female) were included in the study, 83.9% of whom were found to have alexithymia. The incidence of alexithymia in CDK patients was significantly higher than that in the control group (p=0.004); however, no statistically significant difference was detected in its incidence between the hemodialysis and pre-dialysis groups (p & gt;0.05). The results showed that increased incidence of depression resulted in a 4.47-fold (p=0.035) increase in the incidence of alexithymia. Conclusion: Alexithymia has been found to be high in patients with chronic kidney disease. Therefore, it is essential that we be aware of patients’ emotional stress and assess them for depression, anxiety, and alexithymia.
    Type of Medium: Online Resource
    ISSN: 2718-0115
    Language: Unknown
    Publisher: Anatolian Current Medical Journal
    Publication Date: 2023
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  • 4
    Online Resource
    Online Resource
    Journal of Turgut Ozal Medical Center ; 2012
    In:  Journal of Inonu University Medical Faculty Vol. 19, No. 2 ( 2012-04-04), p. 88-95
    In: Journal of Inonu University Medical Faculty, Journal of Turgut Ozal Medical Center, Vol. 19, No. 2 ( 2012-04-04), p. 88-95
    Type of Medium: Online Resource
    ISSN: 1300-1744
    URL: Issue
    Language: Unknown
    Publisher: Journal of Turgut Ozal Medical Center
    Publication Date: 2012
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  • 5
    Online Resource
    Online Resource
    Cagdas Tip Dergisi: Journal of Contemporary Medicine ; 2021
    In:  Journal of Contemporary Medicine Vol. 11, No. 2 ( 2021-03-25), p. 244-247
    In: Journal of Contemporary Medicine, Cagdas Tip Dergisi: Journal of Contemporary Medicine, Vol. 11, No. 2 ( 2021-03-25), p. 244-247
    Abstract: Özet Feokromasitoma sempatik sinir sisteminin kromaffin hücrelerinden gelişen nadir görülen bir tümördür. Hipertansiyon feokromasitomanın en sık bulgusu olmasına rağmen, bu durum çocuklarda erişkinlere göre daha az sıklıkta görülmektedir. Uzun zamandır tanı konulamayan baş ağrısı şikayeti ile başvuran hastamızda gözden kaçırılabilecek bu kliniği değerlendirdik. Hastamız yaklaşık 6 yıldır süren baş ağrısı şikayetinin artması nedeni ile acil servisimize başvurmuş, takibinde nörolojik değerlendirme yapılmıştır. İzleminde kan basıncı yüksekliği saptanması üzerine ileri tetkik edilmiş ve abdominal ultrasonografide sağ sürrenal bezde 36x26x27 mm boyutlarında içerisinde kistik bileşeni bulunan hafif hiperekojen görünümde solid lezyon saptanması, kitlenin manyetik rezonans görüntüleme ve katekolamin yüksekliği ile desteklenmesi ile feokromasitoma tanısı konulmuştur. Olguyu paylaşmamızdaki amacımız hastalarda kan basıncı ölçümünün doğru şekilde ve her muayenede yapılması, persentil çizelgeleri ile değerlendirilmesi ve yakın takibinin önemini vurgulamaktır.
    Type of Medium: Online Resource
    ISSN: 2667-7180
    Language: Unknown
    Publisher: Cagdas Tip Dergisi: Journal of Contemporary Medicine
    Publication Date: 2021
    detail.hit.zdb_id: 3035503-5
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  • 6
    Online Resource
    Online Resource
    Celal Bayar Universitesi Saglık Bilimleri Enstitusu Dergisi ; 2021
    In:  Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Vol. 8, No. 3 ( 2021-09-30), p. 524-533
    In: Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, Celal Bayar Universitesi Saglık Bilimleri Enstitusu Dergisi, Vol. 8, No. 3 ( 2021-09-30), p. 524-533
    Abstract: Giriş: Böbrek hücrelerinin elde edilmesinde kullanılan primer kültür yöntemi, böbrek hastalıklarının hücre düzeyinde değerlendirilmesi ve hücre fonksiyonlarının incelenmesi için olanak sağlamaktadır. Bu çalışmanın amacı böbrek primer kültürü için kullanılabilecek üç farklı izolasyon yönteminin hücre sağkalımı ve protol etkinliği açısından birbirleriyle karşılaştırılmasıdır. Gereç ve Yöntemler: Nefrektomi ile çıkarılan böbrek dokusu steril şartlarda mekanik, tripsin ve kollagenaz yöntemi ile ayrımlanarak podosit vasatı içerisinde kültüre edildi. Kültüre edilen hücrelerin podosin, vimentin, E-kaderin, TGF-β1, CD133, ZO-1 ve Nefrin dağılımlarının analizi immünositokimyasal yöntem ile yapıldı. Bulgular: Kollajenaz enzimatik yöntemi sonrasında hücrelerin kültürün 7. gününden itibaren, mekanik yöntemde ise 13. günden itibaren epiteloid karakter aldıkları gözlenirken, tripsin enzimatik yönteminde 13. günde kültürde artan fuziform yapıdaki hücreler gözlendi. Her üç yöntem ile böbrek dokusundan elde edilen podosit hücrelerin immunositokimyasal analizi sonrasında, elde edilen hücrelerde vimentin, E-kaderin, TGF-β, CD133, ZO-1 immunoreaktiviteleri farklılık gösterir iken, podosin ve nefrin immunoreaktivitelerinin kollajenaz enzimatik yöntemi ile elde edilen hücrelerde kuvvetli olduğu saptandı. Tartışma: Bu çalışmada, farklı proteinlerin immunositokimyasal boyamaları ile kontrol edilen böbrek hücreleri için üç farklı primer kültür teknikleri karşılaştırıldığında, kollajenaz ile muamele edilen böbrek dokusundan daha yüksek verimle hücre saflaştırılabildiği gözlendi. Podosit hücrelerinin kültüre edilmesinde hücre sağkalım verimi ve protokol etkinliği açısından kollajenaz yönteminin en uygun yöntem olduğu gösterildi.
    Type of Medium: Online Resource
    ISSN: 2147-9607
    Language: Unknown
    Publisher: Celal Bayar Universitesi Saglık Bilimleri Enstitusu Dergisi
    Publication Date: 2021
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  • 7
    Online Resource
    Online Resource
    The European Research Journal ; 2023
    In:  The European Research Journal Vol. 9, No. 5 ( 2023-09-04), p. 940-947
    In: The European Research Journal, The European Research Journal, Vol. 9, No. 5 ( 2023-09-04), p. 940-947
    Abstract: Objectives: In this study, we aimed to research the frequency of musculoskeletal manifestations of patients receiving hemodialysis treatment, and evaluate the relationship between quality of life and musculoskeletal manifestations of these patients. Methods: Patients undergoing hemodialysis for at least 6 months were included in our study. Patients were asked to complete a questionnaire that formed by the investigators including demographic, clinical features, and musculoskeletal symptoms that frequently seen in patients who receive hemodialysis. Kidney Disease Quality of Life Short Form Version 1.3 (KDQOL-SF 1.3) and Short Form Health Survey (SF 36) questionnaires were completed by the patients and the control group. Blood urea nitrogen, serum creatinine, serum albumin, C-reactive protein (CRP), parathormone (PTH), ferritin, calcium, phosphate, hemoglobin, and Kt/V were measured. Also, the patients were divided into two subgroups according to musculoskeletal symptoms and these subgroups were compared in terms of dialysis adequacy, quality of life scoring and laboratory findings. Results: Seventy-four patients (42 males, 32 females) were enrolled in our study. The mean age of the patients was 60.85 ± 12.29 years. Six-five (87.83%) patients had musculoskeletal symptoms. There was statistically major difference in terms of smoking between subgroups (p = 0.046). We did not detect any correlation between two groups in terms of Kt/V (p = 0.411). Pain in shoulder/neck (41.9%), pain in limbs (58.1%) and pain in back (56.8%) were the most detected musculoskeletal symptoms of the patients. There was statistically significant difference between genders in terms of joint swelling, muscle cramps, pain in limbs, back and neck /shoulder (p = 0.015, p = 0.001, p = 0.008, p = 0.001, and p = 0.004, respectively). We detected that all subunits of KDQOL scores were higher in control group than patients who were included in our study. There was statistically significant relation between emotional role and energy subunits of KDQOL scores and CRP (p = 0.031 and p = 0.025, respectively). Conclusion: The results of our study were not as significant as the results of similar studies, however they are valuable because they show demographic, clinical characteristics, and quality of life of patients receiving hemodialysis in our region.
    Type of Medium: Online Resource
    ISSN: 2149-3189
    Language: Unknown
    Publisher: The European Research Journal
    Publication Date: 2023
    detail.hit.zdb_id: 2834868-0
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  • 8
    Online Resource
    Online Resource
    Muhendislik Bilimleri ve Tasarim Dergisi ; 2023
    In:  Mühendislik Bilimleri ve Tasarım Dergisi Vol. 11, No. 3 ( 2023-09-28), p. 857-872
    In: Mühendislik Bilimleri ve Tasarım Dergisi, Muhendislik Bilimleri ve Tasarim Dergisi, Vol. 11, No. 3 ( 2023-09-28), p. 857-872
    Abstract: Bulanık kümeler, gerçek hayat problemlerinde belirsizlik olması durumunda çeşitli karar verme problemlerine uygulanmaktadır. Karar verme problemlerinde amaç fonksiyonları ve kısıtlar bazen doğrusal olarak ifade edilemez. Bu gibi durumlarda, ele alınan problemler doğrusal olmayan programlama modelleri ile ifade edilir. Bulanık çok amaçlı programlama modelleri, amaç fonksiyonları ve/veya kısıtların bulanık terimler içerdiği birden fazla amaç fonksiyonu olan problemlerdir. Bulanık çok amaçlı programlama modellerinin çözümünde kullanılan üyelik fonksiyonları, karar verme aşamasında çok önemlidir. Bu çalışmada, bulanık parametrelere sahip bir yeşil tedarik zinciri ağı modeli önerilmiştir. Doğrusal olmayan kısıtları olan model, hem taşıma maliyetlerini hem de taşıma esnasında iki araç tipi tarafından üretilen emisyonları en aza indiren bulanık çok amaçlı doğrusal olmayan programlama modelidir. Model, üçgensel, hiperbolik ve üstel üyelik fonksiyonları gözönüne alınarak Zimmermann'ın Min-Max yaklaşımında kullanılmış ve optimal çözümler elde edilmiştir. Optimal çözümler karşılaştırıldığında, hiperbolik üyelik fonksiyonu kullanılarak elde edilen optimal çözümün üçgensel ve üstel üyelik fonksiyonlarından elde edilen optimal çözümlerden daha iyi olduğu görülmüştür. Önerilen model için hiperbolik üyelik fonksiyonu kullanılarak hesaplanan maksimum ortak memnuniyet düzeyi λ=0.97’dir. Çalışmada, müşteri taleplerinin yanı sıra tedarikçiler, üreticiler, dağıtım merkezleri ve müşteriler arasındaki mesafeler dikkate alınarak duyarlılık analizi de yapılmıştır.
    Type of Medium: Online Resource
    ISSN: 1308-6693
    Language: Unknown
    Publisher: Muhendislik Bilimleri ve Tasarim Dergisi
    Publication Date: 2023
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  • 9
    Online Resource
    Online Resource
    Journal of Infection in Developing Countries ; 2016
    In:  The Journal of Infection in Developing Countries Vol. 10, No. 04 ( 2016-04-28), p. 389-394
    In: The Journal of Infection in Developing Countries, Journal of Infection in Developing Countries, Vol. 10, No. 04 ( 2016-04-28), p. 389-394
    Abstract: Introduction: In this study, clinical, laboratory, radiological, and serological examinations of fascioliasis patients were analyzed, and data with a significant impact on differential diagnosis were evaluated. Methodology: Clinical, radiological, and laboratory findings and treatment responses of a total of 22 fascioliasis patients, treated between October 2009 and September 2014, were evaluated. Nineteen patients were diagnosed with fascioliasis at the invasive phase and three patients at the chronic phase. Patients were followed up for clinical, laboratory, and radiology findings for a period of three months to one year after treatment. Results: The most frequent complaints in both groups were abdominal pain, and the most common physical examination finding was epigastric tenderness. In the performed examination, an eosinophil elevation in whole blood count was detected in 19 patients (100%) in the hepatic phase, and in 2 patients (66.6%) in the biliary phase. The results of the Fasciola hepatica indirect hemagglutination assay (IHA) test ordered in the diagnosis were positive in all patients. Treatment with 10 mg/kg/day triclabendazole for two consecutive days was effective. Live parasites were extracted from patients in the biliary phase with endoscopic retrograde cholangiopancreatography. In the follow-ups, remission in IHA titer and clinical and radiological improvement was achieved in all patients. Conclusions: If hypereosinophilia is detected by peripheral smear in patients who are admitted with complaints such as abdominal pain, weakness, nausea, myalgia, and weight loss, radiological evaluation and serological tests should be performed and fascioliasis should be considered in the differential diagnosis.
    Type of Medium: Online Resource
    ISSN: 1972-2680
    Language: Unknown
    Publisher: Journal of Infection in Developing Countries
    Publication Date: 2016
    detail.hit.zdb_id: 2394024-4
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  • 10
    In: Sağlık Bilimleri Dergisi, Erciyes Universitesi, Vol. 32, No. 2 ( 2023-08-04), p. 164-167
    Abstract: Laringeal maske (LMA)’nin fleksibl fiber optic bronkoskopi (FFB) sırasında kullanımı diğer hava yolu araçlarıyla karşılaştırıldığında daha avantajlıdır. Bu çalışmada, çocuk hastalarda FFB’de hava yolu idamesi için LMA kullanımının uygulama başarı oranları ve karşılaşılan postoperative komplikasyonları hastaların demografik özellikleri, ASA risk grupları, anestezi süresi ve bronkoskopik tanıları ile değerlendirerek literature eşliğinde gözden geçirilmesi planlandı. Ocak 2017 -Ocak 2022 tarihleri arasında FFB yapılan çocuk hastaların dosyaları geriye dönük olarak incelendi. Hastaların demografik verileri, FFB’de hava yolu idamesi için kullanılan hava yolu gereci (LMA, endotrakealtüp, trakealtüp), bronkoskopi endikasyonları, bronkoskopik tanıları, anestezi süresi, işlem sonrası desaturasyon, laringo spazm, bronco spazm ve reentübasyon gereken hasta sayısı kaydedildi. Çalışmaya yaşları 0-17 arasında değişen 162 pediatrik hasta dahil edildi. Median yaş 6.9 (çeyrekler arası aralık 0-17 yaş) ve median ağırlık 24.5 kg (çeyrekler arası aralık 2.5-89) idi. Torasik BT anormallikleri olan ve tanıyı desteklemek için ameliyat gerektiren hasta grubu ensık görülen FOB endikasyonuydu (n=37, %22.8). Toplamda 28 hastada (%17.3) geçici hipoksi, 62 hastada (%38.3) bronco spazm görüldü. Pediatrik hastalarda LMA yoluyla FOB güvenli bir yöntemdir. Uygun ekipman, deneyimli personel, iyi hasta seçimi ve bronkoskopi sonrası hastanın yeterli sure izlemde tutulması komplikasyonların önlenmesinde ve azalmasında en önemli etkenler arasındadır.
    Type of Medium: Online Resource
    ISSN: 1018-3655
    Language: Unknown
    Publisher: Erciyes Universitesi
    Publication Date: 2023
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