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  • 1
    Online Resource
    Online Resource
    Analysis of Light and Light Quality Control of Greenhouse Strawberry Based on BP Neural Network
    DEStech Publications ; 2019
    In:  DEStech Transactions on Computer Science and Engineering , No. iteee ( 2019-03-28)
    Details
    In: DEStech Transactions on Computer Science and Engineering, DEStech Publications, , No. iteee ( 2019-03-28)
    Type of Medium: Online Resource
    ISSN: 2475-8841
    URL: Article
    DOI: 10.12783/dtcse/iteee2019/28734
    Language: Unknown
    Publisher: DEStech Publications
    Publication Date: 2019
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  • 2
    Online Resource
    Online Resource
    Improvement of Inertia Weight Declining Strategy Based on Particle Swarm Optimization Algorithm
    DEStech Publications ; 2019
    In:  DEStech Transactions on Computer Science and Engineering , No. icaic ( 2019-05-20)
    Details
    In: DEStech Transactions on Computer Science and Engineering, DEStech Publications, , No. icaic ( 2019-05-20)
    Type of Medium: Online Resource
    ISSN: 2475-8841
    URL: Article
    DOI: 10.12783/dtcse/icaic2019/29435
    Language: Unknown
    Publisher: DEStech Publications
    Publication Date: 2019
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  • 3
    Online Resource
    Online Resource
    Prediction and Analysis of Water Requirement for Strawberry Growth
    DEStech Publications ; 2019
    In:  DEStech Transactions on Computer Science and Engineering , No. icaic ( 2019-05-20)
    Details
    In: DEStech Transactions on Computer Science and Engineering, DEStech Publications, , No. icaic ( 2019-05-20)
    Type of Medium: Online Resource
    ISSN: 2475-8841
    URL: Article
    DOI: 10.12783/dtcse/icaic2019/29427
    Language: Unknown
    Publisher: DEStech Publications
    Publication Date: 2019
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  • 4
    Online Resource
    Online Resource
    DataSheet_1.pdf
    Frontiers Media SA ; 2022
    In:  Frontiers in Cellular and Infection Microbiology Vol. 12 ( 2022-3-29)
    Details
    In: Frontiers in Cellular and Infection Microbiology, Frontiers Media SA, Vol. 12 ( 2022-3-29)
    Abstract: The effects of hydrogen sulfide (H 2 S) on diabetic metabolic disorders are still controversial, and the mechanisms underlying these effects remain largely unknown. This study was conducted to investigate the potential relationship between the gut microbiota and the improvement of diabetic metabolic disorders by exogenous H 2 S in obese db/db mice. The db/db mice were treated with sodium hydrosulfide (NaHS) (80 μmol/kg), or vehicle for 16 weeks, respectively. We measured the serum H 2 S, obesity parameters, glucose homeostasis, and triglyceride. The sequencing of bacterial 16S rRNA gene and fungal internal transcribed spacer (ITS) in the cecal contents of NaHS-treated mice was performed to evaluate the gut microbial communities. We found that supplying exogenous H 2 S for 16 weeks significantly inhibited the increase of serum triglyceride, blood glucose, and insulin levels and altered specifically the gut bacterial microbiota structure in db/db mice. The relative abundance of some bacterial genera was correlated with the H 2 S or blood glucose level. Indeed, exogenous H 2 S increased Firmicutes and decreased Bacteroidetes at the phylum level along with changes of abundance of multifarious genera. Among them, Unclassified_Enterobacteriaceae , Prevotella , and Lactobacillus decreased and Unclassified_Ruminococcaceae , Oscillospira , Ruminococcus , Sutterella , and Desulfovibrio increased. For fungi, exogenous H 2 S decreased the abundance of Candida and Aspergillus . Here we demonstrated that, in diabetes, microbial dysbiosis may not be just limited to bacteria due to the inter-linked metabolic interactions among bacteria and fungi in the gut. The beneficial effects of exogenous H 2 S on diabetic metabolic disorders are likely associated with the alterations of specific microbiota.
    Type of Medium: Online Resource
    ISSN: 2235-2988
    URL: Article
    URL: Article
    DOI: 10.3389/fcimb.2022.801331
    DOI: 10.3389/fcimb.2022.801331.s001
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2619676-1
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  • 5
    Online Resource
    Online Resource
    The effect of carbon nanoparticles staining on lymph node tracking in colorectal cancer: A propensity score matching analysis
    Frontiers Media SA ; 2023
    In:  Frontiers in Surgery Vol. 10 ( 2023-3-1)
    Details
    In: Frontiers in Surgery, Frontiers Media SA, Vol. 10 ( 2023-3-1)
    Abstract: The aim of this study was to evaluate the effect of carbon nanoparticles staining (CNS) on colorectal cancer (CRC) surgery, lymph node tracing and postoperative complications using propensity score matching (PSM). Method Patients who were diagnosed with CRC and underwent surgery were retrospectively collected from a single clinical center from Jan 2011 to Dec 2021. Baseline characteristics, surgical information and postoperative information were compared between the CNS group and the non-CNS group. PSM was used to eliminate bias. Results A total of 6,886 patients were enrolled for retrospective analysis. There were 2,078 (30.2%) patients in the CNS group and 4,808 (69.8%) patients in the non-CNS group. After using 1: 1 ratio PSM to eliminate bias, there were 2,045 patients left in each group. Meanwhile, all of their baseline characteristics were well matched and there was no statistical significance between the two groups ( P  & gt; 0.05). In terms of surgical information and short-term outcomes, the CNS group had less intraoperative blood loss ( P  & lt; 0.01), shorter operation time ( P   & lt; 0.01), shorter postoperative hospital stay ( P   & lt; 0.01), less metastatic lymph nodes ( P  = 0.013), more total retrieved lymph nodes ( P   & lt; 0.01), more lymphatic fistula ( P  = 0.011) and less postoperative overall complications ( P   & lt; 0.01) than the non-CNS group before PSM. After PSM, the CNS group had less intraoperative blood loss ( P  = 0.004), shorter postoperative hospital stay ( P   & lt; 0.01) and more total retrieved lymph nodes ( P   & lt; 0.01) than the non-CNS group. No statistical difference was found in other outcomes ( P   & gt; 0.05). Conclusion Preoperative CNS could help the surgeons detect more lymph nodes, thus better determining the patient's N stage. Furthermore, it could reduce intraoperative blood loss and reduce the hospital stay.
    Type of Medium: Online Resource
    ISSN: 2296-875X
    URL: Article
    DOI: 10.3389/fsurg.2023.1113659
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2773823-1
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  • 6
    Online Resource
    Online Resource
    Image_5.pdf
    Frontiers Media SA ; 2021
    In:  Frontiers in Microbiology Vol. 12 ( 2021-9-14)
    Details
    In: Frontiers in Microbiology, Frontiers Media SA, Vol. 12 ( 2021-9-14)
    Abstract: Human parechoviruses (HPeVs) are important causes of infection in children. However, without a comprehensive and persistent surveillance, the epidemiology and clinical features of HPeV infection remain ambiguous. We performed a hospital-based surveillance study among three groups of pediatric patients with acute respiratory infection (Group 1), acute diarrhea (Group 2), and hand, foot and mouth disease (Group 3) in Chongqing, China, from 2009 to 2015. Among 10,212 tested patients, 707 (6.92%) were positive for HPeV, with the positive rates differing significantly among three groups (Group 1, 3.43%; Group 2, 14.94%; Group 3, 3.55%; P & lt; 0.001). The co-infection with other pathogens was detected in 75.2% (531/707) of HPeV-positive patients. Significant negative interaction between HPeV and Parainfluenza virus (PIV) ( P = 0.046, OR = 0.59, 95% CI = 0.34–0.98) and positive interactions between HPeV and Enterovirus (EV) ( P = 0.015, OR = 2.28, 95% CI = 1.23–4.73) were identified. Among 707 HPeV-positive patients, 592 (83.73%) were successfully sequenced, and 10 genotypes were identified, with HPeV1 ( n = 396), HPeV4 ( n = 86), and HPeV3 ( n = 46) as the most frequently seen. The proportion of genotypes differed among three groups ( P & lt; 0.001), with HPeV1 and HPeV4 overrepresented in Group 2 and HPeV6 overrepresented in Group 3. The spatial patterns of HPeV genotypes disclosed more close clustering of the currently sequenced strains than those from other countries/regions, although they were indeed mixed. Three main genotypes (HPeV1, HPeV3, and HPeV4) had shown distinct seasonal peaks, highlighting a bi-annual cycle of all HpeV and two genotypes (HPeV 1 and HPeV 4) with peaks in odd-numbered years and with peaks in even-numbered years HPeV3. Significantly higher HPeV1 viral loads were associated with severe diarrhea in Group 2 ( P = 0.044), while associated with HPeV single infection than HPeV-EV coinfection among HFMD patients ( P = 0.001). It’s concluded that HPeV infection was correlated with wide clinical spectrum in pediatric patients with a high variety of genotypes determined. Still no clinical significance can be confirmed, which warranted more molecular surveillance in the future.
    Type of Medium: Online Resource
    ISSN: 1664-302X
    URL: Article
    URL: Article
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    URL: Article
    DOI: 10.3389/fmicb.2021.709849
    DOI: 10.3389/fmicb.2021.709849.s001
    DOI: 10.3389/fmicb.2021.709849.s002
    DOI: 10.3389/fmicb.2021.709849.s003
    DOI: 10.3389/fmicb.2021.709849.s004
    DOI: 10.3389/fmicb.2021.709849.s005
    DOI: 10.3389/fmicb.2021.709849.s006
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2587354-4
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  • 7
    Online Resource
    Online Resource
    Application of Particle Swarm Optimization BP Algorithm in Air Humidity of Greenhouse Crops
    IOP Publishing ; 2019
    In:  IOP Conference Series: Materials Science and Engineering Vol. 565, No. 1 ( 2019-06-01), p. 012003-
    Details
    In: IOP Conference Series: Materials Science and Engineering, IOP Publishing, Vol. 565, No. 1 ( 2019-06-01), p. 012003-
    Abstract: The advancement of artificial intelligence, the synonym of precision agriculture has approached the public’s vision, and the different requirements for air humidity in different growth periods of crops are proposed. The BP neural network optimized by particle swarm optimization algorithm is proposed to predict the air humidity of crops. Algorithm, this paper chooses BP algorithm network topology structure is 2-5-1, improves the inertia weight of PSO algorithm, proposes nonlinear inertia weight reduction strategy w = w s − ( w s − w e ) | f 1 t f | , trains BP algorithm with improved PSO algorithm, has no gradient information, jumps out local pole Value, reduce the number of iterations of the algorithm, and speed up the training speed of the neural network. According to the experimental results of MATLAB simulation, the air humidity prediction model of particle swarm optimization neural network is constructed, which proves the effectiveness of the improved particle swarm neural network prediction system. It can be shown that the proposed algorithm has a relative error of at least 0.0134 compared with other algorithms.
    Type of Medium: Online Resource
    ISSN: 1757-8981 , 1757-899X
    URL: Article
    DOI: 10.1088/1757-899X/565/1/012003
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2019
    detail.hit.zdb_id: 2506501-4
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  • 8
    Online Resource
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    Table_3.DOC
    Frontiers Media SA ; 2021
    In:  Frontiers in Plant Science Vol. 12 ( 2021-10-22)
    Details
    In: Frontiers in Plant Science, Frontiers Media SA, Vol. 12 ( 2021-10-22)
    Abstract: Aroma is an essential quality indicator of oolong tea, a tea derived from the Camellia sinensis L. plant. Carboxylic 6 (C6) acids and their derivative esters are important components of fatty acid (FA)-derived volatiles in oolong tea. However, the formation and regulation mechanism of C6 acid during postharvest processing of oolong tea remains unclear. To gain better insight into the molecular and biochemical mechanisms of C6 compounds in oolong tea, a combined analysis of alcohol dehydrogenase (ADH) activity, CsADH2 key gene expression, and the FA-derived metabolome during postharvest processing of oolong tea was performed for the first time, complemented by CsHIP (hypoxia-induced protein conserved region) gene expression analysis. Volatile fatty acid derivative (VFAD)-targeted metabolomics analysis using headspace solid-phase microextraction–gas chromatography time-of-flight mass spectrometry (HS-SPEM-GC-TOF-MS) showed that the ( Z )-3-hexen-1-ol content increased after each turnover, while the hexanoic acid content showed the opposite trend. The results further showed that both the ADH activity and CsADH gene expression level in oxygen-deficit-turnover tea leaves (ODT) were higher than those of oxygen-turnover tea leaves (OT). The C6-alcohol-derived ester content of OT was significantly higher than that of ODT, while C6-acid-derived ester content showed the opposite trend. Furthermore, the HIP gene family was screened and analyzed, showing that ODT treatment significantly promoted the upregulation of CsHIG4 and CsHIG6 gene expression. These results showed that the formation mechanism of oolong tea aroma quality is mediated by airflow in the lipoxygenase–hydroperoxide lyase (LOX-HPL) pathway, which provided a theoretical reference for future quality control in the postharvest processing of oolong tea.
    Type of Medium: Online Resource
    ISSN: 1664-462X
    URL: Article
    URL: Article
    URL: Article
    URL: Article
    DOI: 10.3389/fpls.2021.738445
    DOI: 10.3389/fpls.2021.738445.s001
    DOI: 10.3389/fpls.2021.738445.s002
    DOI: 10.3389/fpls.2021.738445.s003
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2687947-5
    detail.hit.zdb_id: 2613694-6
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  • 9
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    Relationship between pyroptosis-mediated inflammation and the pathogenesis of prostate disease
    Frontiers Media SA ; 2023
    In:  Frontiers in Medicine Vol. 10 ( 2023-1-19)
    Details
    In: Frontiers in Medicine, Frontiers Media SA, Vol. 10 ( 2023-1-19)
    Abstract: The largest solid organ of the male genitalia, the prostate gland, is comprised of a variety of cells such as prostate epithelial cells, smooth muscle cells, fibroblasts, and endothelial cells. Prostate diseases, especially prostate cancer and prostatitis, are often accompanied by acute/chronic inflammatory responses or even cell death. Pyroptosis, a cell death distinct from necrosis and apoptosis, which mediate inflammation may be closely associated with the development of prostate disease. Pyroptosis is characterized by inflammasome activation via pattern recognition receptors (PRR) upon recognition of external stimuli, which is manifested downstream by translocation of gasdermin (GSDM) protein to the membrane to form pores and release of inflammatory factors interleukin (IL)-1β and IL-18, a process that is Caspase-dependent. Over the past number of years, many studies have investigated the role of inflammation in prostate disease and have suggested that pyroptosis may be an important driver. Understanding the precise mechanism is of major consequence for the development of targeted therapeutic strategies. This review summarizes the molecular mechanisms, regulation, and cellular effects of pyroptosis briefly and then discuss the current pyroptosis studies in prostate disease research and the inspiration for us.
    Type of Medium: Online Resource
    ISSN: 2296-858X
    URL: Article
    DOI: 10.3389/fmed.2023.1084129
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2775999-4
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  • 10
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    Table_7.xlsx
    Frontiers Media SA ; 2022
    In:  Frontiers in Immunology Vol. 13 ( 2022-8-26)
    Details
    In: Frontiers in Immunology, Frontiers Media SA, Vol. 13 ( 2022-8-26)
    Abstract: Arabinogalactan (AG) participates in forming the cell wall core of mycobacteria, a structure known as the mAGP complex. Few studies have reported the virulence of inartificial AG or its interaction with the host immune system. Using clustered regularly interspaced short palindromic repeats interference gene editing technology, conditional Mycobacterium marinum mutants were constructed with a low expression of embA or glfT2 (EmbA_KD or GlfT2_KD), which are separately involved in the biosynthesis of AG arabinose and galactose domains. High-performance gel permeation chromatography and high-performance liquid chromatography assays confirmed that the EmbA_KD strain showed a remarkable decrease in AG content with fragmentary arabinose chains, and the GlfT2_KD strain displayed less reduction in content with cut-down galactose chains. Based on transmission and scanning electron microscopy observations, the cell walls of the two mutants were found to be dramatically thickened, and the boundaries of different layers were more distinct. Phenotypes including the over-secretion of extracellular substances and enhanced spreading motility with a concomitant decreased resistance to ethambutol appeared in the EmbA_KD strain. The EmbA_KD and GlfT2_KD strains displayed limited intracellular proliferation after infecting murine J774A.1 macrophages. The disease progression infected with the EmbA_KD or GlfT2_KD strain significantly slowed down in zebrafish/murine tail infection models as well. Through transcriptome profiling, macrophages infected by EmbA_KD/GlfT2_KD strains showed enhanced oxidative metabolism. The cell survival measured using the CCK8 assay of macrophages exposed to the EmbA_KD strain was upregulated and consistent with the pathway enrichment analysis of differentially expressed genes in terms of cell cycle/apoptosis. The overexpression of C/EBPβ and the increasing secretion of proinflammatory cytokines were validated in the macrophages infected by the EmbA_KD mutant. In conclusion, the AG of Mycobacterium appears to restrain the host innate immune responses to enhance intracellular proliferation by interfering with oxidative metabolism and causing macrophage death. The arabinose chains of AG influence the Mycobacterium virulence and pathogenicity to a greater extent.
    Type of Medium: Online Resource
    ISSN: 1664-3224
    URL: Article
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    DOI: 10.3389/fimmu.2022.879775
    DOI: 10.3389/fimmu.2022.879775.s001
    DOI: 10.3389/fimmu.2022.879775.s002
    DOI: 10.3389/fimmu.2022.879775.s003
    DOI: 10.3389/fimmu.2022.879775.s004
    DOI: 10.3389/fimmu.2022.879775.s005
    DOI: 10.3389/fimmu.2022.879775.s006
    DOI: 10.3389/fimmu.2022.879775.s007
    DOI: 10.3389/fimmu.2022.879775.s008
    DOI: 10.3389/fimmu.2022.879775.s009
    DOI: 10.3389/fimmu.2022.879775.s010
    DOI: 10.3389/fimmu.2022.879775.s011
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2606827-8
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