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  • 1
    Online Resource
    Online Resource
    Measuring Major Adverse Cardiovascular Events (MACE) in male vs female suffering from acute ST-Elevation Myocardial Infarction undergoing Primary Percutaneous Coronary Intervention (PPCI) at PIC, Lahore
    Punjab Institute of Cardiology, Lahore ; 2023
    In:  The Journal of Cardiovascular Diseases Vol. 18, No. 4 ( 2023-04-15)
    Details
    In: The Journal of Cardiovascular Diseases, Punjab Institute of Cardiology, Lahore, Vol. 18, No. 4 ( 2023-04-15)
    Abstract: Introduction: Worldwide, Coronary Artery Diseases (CADs) cause significant disability and death. Primary PCI (PPCI) is the gold-standard of emergency care in management of patients suffering from STEMI. Gender-based differences may be present in the major cardiovascular outcomes (MACE) of PPCI. Objective: This article aims at comparing major adverse cardiovascular outcomes male vs female STEMI patients going through PPCI. Study design: Descriptive case series Study setting: Emergency Department, Punjab Institute of Cardiology (PIC), Lahore. Methodology: With mean age just over 50.3 ± 9.7 years, 193 (78.8%) males and 52 (21.2%) female, a total of 245 patients were enrolled in the study. Risk factors included diabetes, hypertension, familial IHD and active smoking. We recorded in-hospital outcomes post-pPCI: mortality, cerebrovascular accident, acute and subacute stent thrombosis, heart failure, acute kidney injury and arrhythmias. Results: Post PPCI in-hospital outcomes in 193 males: mortality 0, heart failure 3 (1.6%), acute stent thrombosis 0 and acute kidney injury in 11 patients (5.7%). Among 52 females: mortality 2 (3.8%), heart failure 2 (3.8%), acute stent thrombosis 1 (1.9%) and acute kidney injury 3 (5.8%). The only significant association was found between female gender & post PPCI mortality after STEMI (P = 0.006). Conclusion: Results of in-hospital complications among male & female patients following PPCI for acute STEMI seem to show association of female gender with post-PPCI mortality which is significantly greater than the male population under study.
    Type of Medium: Online Resource
    ISSN: 2309-9739 , 2309-3544
    URL: Article
    DOI: 10.55958/jcvd.v18i4.129
    Language: Unknown
    Publisher: Punjab Institute of Cardiology, Lahore
    Publication Date: 2023
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  • 2
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    Online Resource
    COMPARISON THE EFFECTIVENESS OF SITAGLIPTIN VERSUS SULFONYLUREA FOR MANAGEMENT OF PATIENTS WITH TYPE II DIABETES MELLITUS
    Postgraduate Medical Institute, Lahore General Hospital ; 2019
    In:  Pakistan Postgraduate Medical Journal Vol. 30, No. 04 ( 2019-12-28), p. 139-141
    Details
    In: Pakistan Postgraduate Medical Journal, Postgraduate Medical Institute, Lahore General Hospital, Vol. 30, No. 04 ( 2019-12-28), p. 139-141
    Abstract: Background: Type 2 diabetes mellitus (T2DM) is characterized by prolonged hyperinsulinemia, insulin resistance, and progressive hyperglycemia. Current guidelines for treating patients with T2DM are based on glycemic standards. Sitagliptin seems to maintain its positive effects on glycemia and fasting plasma insulin on the long term as compared to sulfonylurea. Objective: To compare the effectiveness of sitagliptin versus sulfonylurea for management of patients with type II diabetes mellitus Methods: it was randomized controlled trial. The data was collected in North medical ward, department of medicine Mayo hospital Lahore. The patients were randomly divided into two groups e.g Group A Sitagliptin and group B sulfonylurea. The blood sample were drawn at baseline and after 12 weeks for HbA1c level. Results: In Sitagliptin group, the mean age of patients was 57.93±13.10years. In sulfonylurea group, the mean age of patients was 63.51±11.23years. There were 35 (50.0%) male and 35 (50.0%) females in Sitagliptin group. There were 31 (44.3%) male and 39 (55.7%) females in sulfonylurea group. There was 1.19±1.00% decrease in HbA1c with sitagliptin and 0.53±0.31% with sulfonylurea. The difference was significant (p 〈 0.05). In our trial, effectiveness was achieved in 50 (71.4%) with sitagliptin while in 33 (47.1%) with sulfonylurea. The difference was significant (p 〈 0.05). Conclusion: Thus, Sitagliptin is more effective and control more HbA1c than sulfonylurea for management of T2DM
    Type of Medium: Online Resource
    ISSN: 2710-1924 , 2079-5858
    URL: Issue
    URL: Article
    DOI: 10.51642/ppmj.v30i04
    DOI: 10.51642/ppmj.v30i04.564
    Language: Unknown
    Publisher: Postgraduate Medical Institute, Lahore General Hospital
    Publication Date: 2019
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  • 3
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    Online Resource
    Comparing the Frequency of Left Main Stem Disease Among Patients with ST Elevation in AVR Lead
    Allama Iqbal Medical college, Lahore ; 2023
    In:  JAIMC: Journal of Allama Iqbal Medical College Vol. 21, No. 2 ( 2023-09-19)
    Details
    In: JAIMC: Journal of Allama Iqbal Medical College, Allama Iqbal Medical college, Lahore, Vol. 21, No. 2 ( 2023-09-19)
    Abstract: Background: Coronary artery disease (CAD) is one of the leading causes of mortality worldwide with similar prevalence in Pakistan. The main objective of the study is to compare the frequency of left main stem disease among patients with STelevation in aVR. Methods:This cross-sectionalstudywas conducted inDepartment of cardiology,Punjab institute of cardiology,Lahore. Sample size of 151 cases is calculated with 95% confidence level,7%margin of error and taking expected percentage of LMS is 74.2%. The data was collected through non probability consecutive sampling technique. Results: Mean age of the study population was 55.54±10.1 years. Majority of the cases were male 117(77.5%)and 34(22.5%) were female which were less in quantity. Mean body mass index was 28.61±2.58. Conclusion: Majority of the cases developed left mainstem disease who have been diagnosed with STelevation in aVR. A significant difference of the diabetic versus non diabetic was observed who have been noted for LMS disease.
    Type of Medium: Online Resource
    ISSN: 2958-5945 , 2076-2860
    URL: Issue
    URL: Article
    DOI: 10.59058/jaimc.v21i2
    DOI: 10.59058/jaimc.v21i2.170
    Language: Unknown
    Publisher: Allama Iqbal Medical college, Lahore
    Publication Date: 2023
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  • 4
    Online Resource
    Online Resource
    Comparison between adverse effects of I/v Inj Labetalol Vs Inj Hydralazine during treatment of Hypertension in pregnancy
    Lahore Medical and Dental College ; 2023
    In:  Pakistan Journal of Medical and Health Sciences Vol. 17, No. 6 ( 2023-06-16), p. 34-36
    Details
    In: Pakistan Journal of Medical and Health Sciences, Lahore Medical and Dental College, Vol. 17, No. 6 ( 2023-06-16), p. 34-36
    Abstract: Aim: To examine and compare side effects of intravenous Labetalol and Hydralazine in the treatment of Hypertension in pregnancy in developing countries like Pakistan. Methodology: A six-month randomised controlled experiment was undertaken at the Lady Aitchison Hospital's, Department of Obstetrics and Gynaecology. In the study, 330 individuals with severe hypertension who were between the ages of 20 and 35 years old and had been pregnant for more than 20 weeks were included. Patients were split into two groups of equal size. Group A was administered a 20mg IV bolus of Labetalol while Group B was administered a 5-10mg IV bolus of Hydralazine. The patients were monitored during the administration period of 60 minutes and all this data was entered into a proforma. Results: Females had an average age of 27.43±3.47 years and average gestational age in females was 28.98±4.49 weeks. The systolic blood pressure in all females was 109.43 ±16.93mmHg after 60 minutes of therapy, and mean diastolic blood pressure was 77.28±14.73mmHg. A total of 135(40.9%) women suffered from maternal hypotension [27(16.36%) with Labetalol vs 108(65.43%) with Hydralazine], and 55(16.68%) females exhibited abnormal fetal heart rate [1 (0.61%) with Labetalol and 54(32.72%) with Hydralazine] . Therefore, the Hydralazine adverse effect was statistically significant (p-value = 0.000). Practical Implication: If the results of this study are applied in clinical practice in patients of pregnancy induced hypertension, female patients ca be prevented of side effects of hydralazine by using labetalol to treat hypertension in pregnancy, so it is very beneficial for patients. Conclusion: The study concludes that use of Hydralazine in females with PIH should be discouraged, whereas the use of Labetalol should be encouraged in a developing country like Pakistan. Keywords: Pregnancy Induced Hypertension (PIH),Gestational Hypertension(GH), hypotension, headache, abnormal fetal heart rate, palpitation, tachycardia, intravenous.
    Type of Medium: Online Resource
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.53350/pjmhs2023176
    DOI: 10.53350/pjmhs202317
    DOI: 10.53350/pjmhs202317634
    Language: Unknown
    Publisher: Lahore Medical and Dental College
    Publication Date: 2023
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