In:
Clinical Chemical Laboratory Medicine, Walter de Gruyter GmbH, Vol. 45, No. 11 ( 2007-01-01)
Abstract:
In this comprehensive review, we summarize the current state-of-the-art of neurochemical biomarkers for Alzheimer's disease. Predominantly, these biomarkers comprise cerebrospinal fluid biomarkers directly related to the pathophysiology of this disorder (such as amyloid β protein, tau protein). We particularly pay attention to the innovations in this area that have been made in technological aspects during the past 5 years (e.g., multiplex analysis of biomarkers, proteomics), to the discovery of novel, potential biomarkers (e.g., amyloid β oligomers, isoprostanes), and to the extension of this research towards identification of biomarkers in plasma. Clin Chem Lab Med 2007;45:1421–34.
Type of Medium:
Online Resource
ISSN:
1437-4331
,
1434-6621
DOI:
10.1515/CCLM.2007.320
Language:
Unknown
Publisher:
Walter de Gruyter GmbH
Publication Date:
2007
detail.hit.zdb_id:
1492732-9
SSG:
15,3
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