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    In: European Journal of Endocrinology, Oxford University Press (OUP), Vol. 183, No. 1 ( 2020-07), p. 1-11
    Abstract: Little is known about how lifestyle affects psychological well-being in overweight women with polycystic ovary syndrome (PCOS). We investigated the effects of behavioral modification on psychological well-being and the impact of well-being and personality traits on successful weight loss. Design A 4-month randomized controlled trial with a 12-month follow-up at a University Hospital. Methods Sixty-eight women with PCOS, aged 18 to 40 years with a BMI ≥27 kg/m 2 , were randomized (1:1) into a behavioral modification program (intervention) or minimal intervention (control). The outcome measures were the psychological well being index and the Swedish universities scales of personality. Results At baseline, 60% had a global psychological well being index corresponding to severe distress and 40% to moderate distress. There was no significant change in mean global well-being score at 4 months within or between groups. However, after 4 months, the intervention group expressed less anxiety ( P  = .035), higher general health ( P  = .012) and lower depressed mood ( P  = .033). Anxiety and general health tended to differ between groups ( P  = .06, respectively) favoring intervention. In the whole population, women achieving ≥5% weight loss at 12 months ( n  = 18) were less anxious at baseline compared to those who had not ( P  = .004). Personality trait-analysis showed that the weight-loss group had higher social desirability ( P  = .033) and lower embitterment ( P  = .023). Conclusions Psychological well-being is severely impacted in overweight women with PCOS. Behavioral modification can positively impact dimensions of well-being, although not fully significant, compared to control treatment. Personality factors could contribute to the understanding of successful weight loss.
    Type of Medium: Online Resource
    ISSN: 0804-4643 , 1479-683X
    RVK:
    Language: Unknown
    Publisher: Oxford University Press (OUP)
    Publication Date: 2020
    detail.hit.zdb_id: 1485160-X
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