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  • 1
    In: Bangladesh Journal of Medicine, Bangladesh Academy of Sciences, Vol. 32, No. 2 ( 2021-06-05), p. 99-106
    Abstract: Background and aims: Acute pancreatitis is the most common major post-ERCP complication ranging as high as 10% to 40%. Rectal NSAIDS (Indomethacin or Diclofenac) seem to be the most promising drugs to prevent post ERCP pancreatitis. We performed a trial to investigate the efficacy of indomethacin or diclofenac. Methods: A prospective randomized comparative trial was performed at Dhaka from January 2013 to June 2019. Patients undergoing ERCP were randomly selected to group-A and group-B. Diclofenac 50mg suppository was given to group-A patients and Indomethacin 100mg suppository was given to group-B patients during or just after ERCP. The primary outcome was acute pancreatitis following the procedure which was defined by new upper abdominal pain, elevation of pancreatic lipase to at least 3 times the upper limit of normal level 24 hours after ERCP and hospitalization for 02 nights. Retrospective analysis of data of 122 patients who had undergone ERCP in 2012 but had no history of rectal NSAIDS (group C) was done. Results: Total 613 patients were included in this study and followed up. Post ERCP pancreatitis developed in 21(8.5%) patients of group-A (n=247), in 19(7.78%) patients of group-B (n=244) and in 20(17.85%) patients of group-C (n=122)(p=0.02). Moderate to severe pancreatitis was found in 08(3.23%) patients of group-A, in 06(2.45%) patients of group-B and in 12(9.83%) patients of group-C(p= 0.01). Administration of these NSAIDS showed clear benefit to reduce occurrence of Post ERCP pancreatitis when compared with no drug group (P=0.01). The efficacy of indomethacin compared with diclofenac was similar (P=0.874). Conclusions: Prophylactic use of rectal indomethacin or diclofenac during or just after ERCP significantly reduces the incidence of post ERCP pancreatitis. These NSAIDs are inexpensive, safe and should be used routinely in each patient undergoing ERCP. Bangladesh J Medicine July 2021; 32(2) : 99-106
    Type of Medium: Online Resource
    ISSN: 2408-8366 , 1023-1986
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2021
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  • 2
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    Bangladesh Academy of Sciences ; 2021
    In:  Medicine Today Vol. 33, No. 1 ( 2021-02-25), p. 1-6
    In: Medicine Today, Bangladesh Academy of Sciences, Vol. 33, No. 1 ( 2021-02-25), p. 1-6
    Abstract: Introduction: Upper abdominal pain is found to be one of the most common presenting symptoms. Endoscopic ultrasound may be a useful tool to yield a specific diagnosis. Aim of our study was to find the etiology of upper abdominal pain with normal endoscopic findings and compare the findings of endoscopic ultrasound with those of trans-abdominal ultrasound. Materials and Methods: This was a cross sectional study conducted in the department of gastroenterology, Sir Salimullah Medical College from January 2015 to December 2019. Total 238 patients suffering from upper abdominal pain who previously underwent endoscopy with normal results and trans abdominal ultrasound with doubtful findings were enrolled in this study. All patients were evaluated properly with history, clinical examination and relevant blood investigations. Then the patients underwent endoscopic ultrasound with conscious sedation. Computed tomorgraphy, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography were done in cases where needed and correlated with endoscopic ultrasound results. Results: Among the total 238 patients, 137 were male and 101 were female. Most predominant age range was 31-40 years. Pain was moderate in severity in 43.27%, epigastric pain was in 59.66% and pain referred to back was in 37.39% patients. Comparison with trans abdominal ultrasound regarding etiologies of upper abdominal pain was statistically significant (P=0.000). Comparative analysis between the two modalities regarding gall bladder, common bile duct, pancreas were also found significant with P values of 0.040, 0.005, 0.000 respectively. Forty two patients were diagnosed as chronic pancreatitis based on Rosemont criteria by endoscopic ultrasound. Conclusion: Endoscopic ultrasound is a modern diagnostic tool which can detect hepato-pancreato-biliary pathologies and also mucosal irregularities of stomach and esophagus. So, it can be considered as a first line investigation to diagnose the underlying etiology of upper abdominal pain. Medicine Today 2021 Vol.33(1): 1-6
    Type of Medium: Online Resource
    ISSN: 2408-8714 , 1810-1828
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2021
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  • 3
    In: Medicine Today, Bangladesh Academy of Sciences, Vol. 34, No. 1 ( 2022-04-24), p. 1-5
    Abstract: Introduction with objective: This study was done to see the serum bilirubin level of patients with self reporting jaundice without clinical jaundice. Materials and Methods: This study was done from January 2019 to January 2020 at Popular Medical Centre, Sylhet. Consecutive patients claiming to have jaundice without clinical icterus were included. Demographical information and presenting symptoms were noted. Serum bilirubin and relevant l aboratory investigations were done and results were noted. Statistical analysis was done using SPSS 20. Results: Total 177 patients, age varying from six years to 80 years (mean 28.54) were included. Of them 134 (75.7%) were male. Common symptoms for were anorexia (90; 50.8%), pain abdomen (76; 42.9%), weakness (49; 27.7%), nausea (45; 25.4%), fullness of abdomen (35; 19.8%), gas (34; 19.2%) and vomiting (16; 9%). Of them 164 (92.7%) initially visited kabiraj. Serum bilirubin level of them varied from 0.04 mg/ dl to 2.67 mg / dl (mean 0.814±0.577) and ALT level varied from 10 iu/ dl to 2944 iu/ dl (mean 71.55±270.09). In this series 143 (80.0%) patients had no jaundice biochemically. Among others, 08 (4.52%) were case of acute hepatitis and 13 (7.34%) were possible cases of Gilbert’s syndrome. Patients’ attitude regarding informal caregivers significantly differed with education level. Conclusion: Most of patients claiming to have jaundice without icterus had no evidence of liver disease. Consulting kabiraj they are wasting money and sometimes inviting health related disasters. So mass education and motivation may increase awareness of people regarding liver disease and prevent health hazards. Medicine Today 2022 Vol.34(1): 01-05
    Type of Medium: Online Resource
    ISSN: 2408-8714 , 1810-1828
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2022
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  • 4
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    Bangladesh Academy of Sciences ; 2014
    In:  Journal of Enam Medical College Vol. 4, No. 2 ( 2014-07-09), p. 79-88
    In: Journal of Enam Medical College, Bangladesh Academy of Sciences, Vol. 4, No. 2 ( 2014-07-09), p. 79-88
    Abstract: Background: Upper gastrointestinal (GI) symptoms are common complaints affecting 25--40% of the general population and are common causes of health care utilisation and substantially affect the quality of life. In day-to-day practice our clinicians have to face good number of patients with various upper GI symptoms. But we have limited data on the prevalence of different upper GI symptoms in our community. Objective: The present study aimed to find out the prevalence of different upper GI symptoms in the general population of a district in Bangladesh. Materials and Methods: This population-based observational study was conducted in a selected district of Bangladesh. Three thousand subjects selected by cluster sampling method were interviewed by a valid bowel disease questionnaire. Students t test and chi-square tests were used for comparison of different variables with significance level set at 0.05. Results: Among the study population 1523 were men and 1477 were women with a mean age of 33.91 ± 16.43 years. A total of 2273 (75.8%) persons had at least one upper GI symptom, 2072 (69.1%) had 2 or more symptoms and 1705 (56.8%) had 3 or more symptoms in the prior 3 months. Nine hundred sixty three subjects (32.1%) had upper abdominal pain, 1265 (42.16%) had bloating, 1354 (45.13%) had heart-burn, 1166 (38.87%) had chest pain, 1347 (44.9%) had early satiation and 258 (8.6%) had vomiting. Around 249 (8.3%, male 123, female 126, P=0.691) was diagnosed as functional dyspepsia, 187 (6.2%, male 82, female 105, P=0.059) as gastroesophageal reflux disease (GERD) and 55 (1.83%, male 27, female 28, P=0.892) as upper abdominal bloating. Only one woman fulfilled the criteria for functional gallbladder or sphincter of Oddi dysfunction. Approximately 40.56% dyspeptic patients had overlapping GERD symptoms. Symptom prevalence was found to decrease with increased number, frequency and duration of symptoms. Conclusion: Upper GI symptoms are prevalent in our community. Multiple upper GI symptoms do exist simultaneously. Symptom prevalence varies with number, frequency and duration of symptoms. DOI: http://dx.doi.org/10.3329/jemc.v4i2.19458 J Enam Med Col 2014; 4(2): 79--88
    Type of Medium: Online Resource
    ISSN: 2304-9316 , 2227-6688
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2014
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  • 5
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    Bangladesh Academy of Sciences ; 2019
    In:  Journal of Current and Advance Medical Research Vol. 6, No. 1 ( 2019-03-27), p. 42-46
    In: Journal of Current and Advance Medical Research, Bangladesh Academy of Sciences, Vol. 6, No. 1 ( 2019-03-27), p. 42-46
    Abstract: Background: Diseases of gastrointestinal tract are a major cause of morbidity and mortality. Objective: This study was carried out to determine the spectrum of histopathological lesions of upper gastrointestinal tract. Methodology: This retrospective study was conducted in the Department of Pathology at North East Medical College, Sylhet, Bangladesh during a 36 months period from January 2013 to December 2015. Endoscopies were performed using Olympus 150, forward viewing upper GI endoscope. The biopsy specimens received were fixed in 10.0% formalin and routinely processed in Haematoxyline & Eosin stain. Results: The present study included 135 endoscopic biopsies. The mean age with SD of the study population was 53.20±16.09 years. Among 53 cases of esophageal biopsies 8(15.08%) cases showed non-neoplastic lesions and 45(84.92%) cases were neoplastic of which 39(73.6%) cases and 6(11.32%) cases were squamous cell carcinoma and adenocarcinoma respectively. Among 6 cases of gastro esophageal junction biopsies 3(50%) cases showed non-neoplastic lesions and 3(50%) were neoplastic, of which 2(33.33%) were adenocarcinoma and 1(16.67%) were squamous cell carcinoma. Among 61 cases of stomach biopsies 34(55.74%) showed non-neoplastic lesions and 27(44.26%) were neoplastic, of which 1(1.64%) case was adenoma and 25(40.98%) were adenocarcinoma. Among 15 cases of duodenal biopsies 13(86.67%) cases showed non-neoplastic lesions and 2(13.33%) were neoplastic one of which was adenocarcinoma (6.67%). Among 135 cases endoscopist reported 82(60.74%) cases as neoplastic and 53(39.26%) as non-neoplastic, whereas histopathology revealed 77(57.03%) cases neoplastic and 58(42.97%) cases non-neoplastic. Conclusion: Common site of upper GIT endoscopic biopsy is stomach which are mostly neoplastic lesion; however, most common malignancy is squamous cell carcinoma of the oesophagus. Journal of Current and Advance Medical Research 2019;6(1):42-46
    Type of Medium: Online Resource
    ISSN: 2413-323X , 2313-447X
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2019
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  • 6
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    Bangladesh Academy of Sciences ; 2018
    In:  Journal of Shaheed Suhrawardy Medical College Vol. 9, No. 1 ( 2018-07-05), p. 6-9
    In: Journal of Shaheed Suhrawardy Medical College, Bangladesh Academy of Sciences, Vol. 9, No. 1 ( 2018-07-05), p. 6-9
    Abstract: Background: Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorder with absence of organic damages to the intestine. The pathophysiology of IBS is still not completely understood, but in some cases psychological disorders may affect the onset and outcome of IBS. Some studies have found disparities between subtypes of irritable bowel syndrome (IBS) regarding socio-demographic characteristics and lifestyle factors.Methods: This cross-sectional study aimed to investigate whether there are differences in sociodemographic and lifestyle factors including smoking and physical activity between the subtypes of IBS. The study was performed on outpatients diagnosed as irritable bowel syndrome (from January 2015 to December 2015) in Dhaka Medical College Hospital and Shaheed Suhrawardy Medical College Hospital in Dhaka. A total of purposively selected 208 diagnosed IBS patients were interviewed by semi-structured questionnaire in which subtype of irritable bowel syndrome were measured by Rome-III criteria regarding stool consistency.Results: Mean age of the respondents was 32.3 (+ 10.32) years and majority of them were male (77%), married (66.8%), educated up to secondary level (35.6%), labour (skilled and unskilled) (30%), non- smoker (67.3%) and HEPA (health enhancing physical activity) active (65.9%). Diarrhea predominant irritable bowel syndrome (50%) was found the most common subtype among the irritable bowel syndrome respondents followed by mixed type irritable bowel syndrome (42%) and constipation predominant irritable bowel syndrome (8%) There were no statistical differences found between constipation predominant irritable bowel syndrome ( IBS-C), Diarrhea predominant irritable bowel syndrome (IBS-D), and mixed type irritable bowel syndrome (IBSM) patients regarding to socio-demographic characteristics and lifestyle factors (P 〈 0.05).Conclusion: Our study concluded that there are no different socio-demographic and lifestyle characteristics between IBS subtypes.J Shaheed Suhrawardy Med Coll, June 2017, Vol.9(1); 6-9
    Type of Medium: Online Resource
    ISSN: 2226-5368
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2018
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  • 7
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    Bangladesh Academy of Sciences ; 2013
    In:  Journal of the Asiatic Society of Bangladesh, Science Vol. 38, No. 1 ( 2013-06-16), p. 7-15
    In: Journal of the Asiatic Society of Bangladesh, Science, Bangladesh Academy of Sciences, Vol. 38, No. 1 ( 2013-06-16), p. 7-15
    Abstract: Nine bottled water brands collected from retail shops and food shops beside the University of Dhaka were analyzed for their major and trace element constituents to ascertain their suitability for human consumption. The results obtained were compared with parametric values (PVs) set by European Community Council Directive 98/83/EC and the guideline values (GVs) recommended by WHO. It was found that the majority of the brands tested were low in mineral contents. Moreover, lower values of hardness, TDS and conductivity than the prescribed limits of WHO showed that water was deficient in essential minerals. Minerals like magnesium, potassium, calcium were present in some cases in such a low concentration that water seemed to be as good as distilled water. In case of heavy metals, only lead and cadmium were found to be below the detection limit (0.001 mg/L) which indicates bottled water brands are better for drinking. DOI: http://dx.doi.org/10.3329/jasbs.v38i1.15316 J. Asiat. Soc. Bangladesh, Sci. 38(1): 7-15, June 2012
    Type of Medium: Online Resource
    ISSN: 2408-8676 , 1016-6947
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2013
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  • 8
    In: Bangladesh Heart Journal, Bangladesh Academy of Sciences, Vol. 33, No. 2 ( 2018-12-28), p. 90-93
    Abstract: Background: The effect of late percutaneous coronary intervention on left ventricular function is incompletely understood. Objectives: To evaluate the effect of late Percutaneous Coronary Intervention on LV systolic function following coronary stenting after acute anterior myocardial infarction. Methods: A total of 60 patients, 〉 24 hours to 6 weeks after anterior AMI who attended in UCC, BSMMU between July 2014 to June 2015 were included in this study. They underwent coronary stenting. After coronary stenting all patients were in TIMI flow-3. Serial echocardiographic assessment of LV function before and after late intervention with modified Simpson’s rule in apical 4 chamber view as well as comparison between baseline result with that of after intervention were done. The patients were on standard medical therapy in post intervention period. Result: Mean age was 54.3±8.91 years with minimum 30 years and maximum 75 years. Most of the patients were male (67%). LVESV was 60.0±14.4 ml before PCI and 58.3±15.3 ml at discharge (p value 0.091) & 44.1±17.6 ml after 3 months (p value 〈 0.001). LVEF was 40.2±3.1% before PCI, 40.2±3.3% at discharge (p value 0.509) & 47.6±5.9% after 3 months (p value 〈 0.001). There was no significant improvement of LV function from baseline till discharge but significant improvement occurred after 3months. Conclusion: Using echocardiographic techniques, our results showed that left ventricular volume decreased and the left ventricular ejection fraction increased significantly after three months of late intervention. Bangladesh Heart Journal 2018; 33(2) : 90-93
    Type of Medium: Online Resource
    ISSN: 2521-3113 , 1024-8714
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2018
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  • 9
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    Bangladesh Academy of Sciences ; 2018
    In:  Journal of Bangladesh College of Physicians and Surgeons Vol. 37, No. 1 ( 2018-12-18), p. 25-29
    In: Journal of Bangladesh College of Physicians and Surgeons, Bangladesh Academy of Sciences, Vol. 37, No. 1 ( 2018-12-18), p. 25-29
    Abstract: Introduction: Abdominal tuberculosis is not uncommon in daily medical practice. This study was done focusing variable presentations of abdominal tuberculosis Material and methods: Data of consecutive patients diagnosed as abdominal tuberculosis were analyzed. Their epidemiological features, presentations, laboratory findings, and response to therapy were analysed. Result: Total 69 cases (male 43, 62.3%,and female 26, 37.7%), age ranging from 15 to 85 years (mean 36.23) were enrolled. Rural (55, 79.7%), poor (49,71%) and housewives (24, 34.8%) and people of 21-30 years age group (27, 39.1%) were more affected. Diagnosis was based on combinations of clinical, laboratory findings and therapeutic response. In this series 30 (43.5%), 23 (33.4%) and 12 (17.3%) were diagnosed as intestinal, peritoneal and disseminated tuberculosis respectively. Of them68 patients recovered with treatment. Five patients developed intestinal obstruction and one developed hepatitis and lost from follow up. Conclusion: Diagnosis of abdominal tuberculosis is by combinations of clinical findings, without gold standard method. In our series intestinal tuberculosis and peritoneal tuberculosis were common clinical types with weight loss and abdominal pain as common clinical symptoms. And outcome of Treatment of TB was excellent J Bangladesh Coll Phys Surg 2019; 37(1): 25-29  
    Type of Medium: Online Resource
    ISSN: 1015-0870
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2018
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  • 10
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    Bangladesh Academy of Sciences ; 2023
    In:  Journal of Bangladesh College of Physicians and Surgeons Vol. 41, No. 3 ( 2023-07-27), p. 237-238
    In: Journal of Bangladesh College of Physicians and Surgeons, Bangladesh Academy of Sciences, Vol. 41, No. 3 ( 2023-07-27), p. 237-238
    Abstract: Gastric xanthoma, although benign lesion, sometimes resemble to neoplasm.  It is more common in older age group. Histologically it contains lipid ladenhistiocytes. But it should be differentiated from malignancy. So proper attention during endoscopic examination and relevant investigations to exclude malignancy should be considered in every patients with gastric xanthoma. J Bangladesh Coll Phys Surg 2023; 41: 237-238
    Type of Medium: Online Resource
    ISSN: 1015-0870
    Language: Unknown
    Publisher: Bangladesh Academy of Sciences
    Publication Date: 2023
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