GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Analgesic effects of carprofen and liposome-encapsulated butorphanol tartrate in Hispaniolan parrots (Amazona ventralis) with experimentally induced arthritis
    American Veterinary Medical Association (AVMA) ; 2009
    In:  American Journal of Veterinary Research Vol. 70, No. 10 ( 2009-10), p. 1201-1210
    Details
    In: American Journal of Veterinary Research, American Veterinary Medical Association (AVMA), Vol. 70, No. 10 ( 2009-10), p. 1201-1210
    Abstract: Objective —To evaluate the microcrystalline sodium urate (MSU) method for inducing arthritis in parrots and to compare the analgesic efficacy of long-acting liposome-encapsulated butorphanol (LEBT), carprofen, or a combination of both. Animals —20 Hispaniolan parrots. Procedures —MSU was injected into a tibiotarsal-tarsometatarsal (intertarsal) joint to induce arthritis (time 0). Four treatments were compared (LEBT [15 mg/kg, SC] administered once at time 0; injections of carprofen [3 mg/kg, IM, q 12 h] starting at time 0; administration of LEBT plus carprofen; and a control treatment of saline [0.9% NaCl] solution). Weight load testing and behavioral scoring were conducted at 0, 2, 6, 26, and 30 hours. Results —Injection of MSU into the intertarsal joint induced arthritis, which resolved within 30 hours. Treatment with LEBT or LEBT plus carprofen resulted in significantly greater weight-bearing load on the limb with induced arthritis, compared with the control treatment. Treatment with carprofen alone caused a slight but nonsignificant improvement in weight-bearing load on the arthritic limb, compared with the control treatment. Behaviors associated with motor activity and weight bearing differed between the control and analgesic treatments. Conclusions and Clinical Relevance —Butorphanol was an effective treatment for pain associated with arthritis, but carprofen administered every 12 hours was insufficient. Injection of MSU to induce arthritis in a single joint was a good method for evaluating tonic pain in parrots, and measurement of the weight-bearing load was accurate for assessment of arthritic pain; however, behavioral changes associated with pain were subtle.
    Type of Medium: Online Resource
    ISSN: 0002-9645
    URL: Article
    DOI: 10.2460/ajvr.70.10.1201
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2009
    detail.hit.zdb_id: 2056942-7
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Evaluation of liposome-encapsulated butorphanol tartrate for alleviation of experimentally induced arthritic pain in green-cheeked conures (Pyrrhura molinae)
    American Veterinary Medical Association (AVMA) ; 2009
    In:  American Journal of Veterinary Research Vol. 70, No. 10 ( 2009-10), p. 1211-1219
    Details
    In: American Journal of Veterinary Research, American Veterinary Medical Association (AVMA), Vol. 70, No. 10 ( 2009-10), p. 1211-1219
    Abstract: Objective —To evaluate injection of microcrystalline sodium urate (MSU) for inducing articular pain in green-cheeked conures ( Pyrrhura molinae ) and the analgesic efficacy of liposome-encapsulated butorphanol tartrate (LEBT) by use of weight load data, behavioral scores, and fecal corticosterone concentration. Animals —8 conures. Procedures —In a crossover study, conures were randomly assigned to receive LEBT (15 mg/kg) or liposomal vehicle subsequent to experimental induction of arthritis or sham injection. The MSU was injected into 1 tibiotarsal-tarsometatarsal (intertarsal) joint to induce arthritis (time 0). Weight-bearing load and behavioral scores were determined at 0, 2, 6, 26, and 30 hours. Results —MSU injection into 1 intertarsal joint caused a temporary decrease in weight bearing on the affected limb. Treatment of arthritic conures with LEBT resulted in significantly more weight bearing on the arthritic limb than treatment with vehicle. Administration of vehicle to arthritic conures caused a decrease in activity and feeding behaviors during the induction phase of arthritis, but as the arthritis resolved, there was a significant increase in voluntary activity at 30 hours and feeding behaviors at 26 and 30 hours, compared with results for LEBT treatment of arthritic birds. Treatment with LEBT or vehicle in conures without arthritis resulted in similar measurements for weight bearing and voluntary and motivated behaviors. Conclusions and Clinical Relevance —Experimental induction of arthritis in conures was a good method for evaluating tonic pain. Weight-bearing load was the most sensitive measure of pain associated with induced arthritis. Pain associated with MSU-induced arthritis was alleviated by administration of LEBT.
    Type of Medium: Online Resource
    ISSN: 0002-9645
    URL: Article
    DOI: 10.2460/ajvr.70.10.1211
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2009
    detail.hit.zdb_id: 2056942-7
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Serum concentrations and analgesic effects of liposome-encapsulated and standard butorphanol tartrate in parrots
    American Veterinary Medical Association (AVMA) ; 2006
    In:  American Journal of Veterinary Research Vol. 67, No. 5 ( 2006-05), p. 775-781
    Details
    In: American Journal of Veterinary Research, American Veterinary Medical Association (AVMA), Vol. 67, No. 5 ( 2006-05), p. 775-781
    Abstract: Objective —To compare serum concentrations of liposome-encapsulated butorphanol tartrate (LEBT) and standard butorphanol tartrate (STDBT) following SC and IM administration, respectively, and to evaluate analgesic effects of LEBT and STDBT after parenteral administration to Hispaniolan parrots. Animals —11 adult Hispaniolan parrots. Procedure —The ability of LEBT to prolong the duration of analgesia in an avian species was tested. Blood samples were collected at serial time points after SC administration of LEBT (10 mg/kg or 15 mg/kg) or IM administration of STDBT (5 mg/kg). Serum concentrations of butorphanol tartrate were determined by use of a commercial immunoassay that measured parent drug and metabolites. Analgesic efficacy was evaluated in parrots exposed to electrical and thermal stimuli. Foot withdrawal thresholds were recorded at baseline and at serial time points after LEBT (15 mg/kg), liposome vehicle, STDBT (2 mg/kg), or physiologic saline (0.9% NaCl) solution administration. Results —LEBT had a prolonged in vivo release for up to 5 days. Negligible serum butorphanol and butorphanol metabolite concentrations were obtained at 24 hours after IM administration of STDBT. Analgesic efficacy of LEBT as measured by foot withdrawal threshold to noxious thermal and electrical stimuli persisted for 3 to 5 days following SC administration of LEBT. Conclusions and Clinical Relevance —SC administration of LEBT provided analgesia and detectable serum butorphanol concentrations in Hispaniolan parrots for up to 5 days. The use of LEBT may allow for substantial improvement in long-term pain relief without subjecting birds to the stress of handling and multiple daily injections.
    Type of Medium: Online Resource
    ISSN: 0002-9645
    URL: Article
    DOI: 10.2460/ajvr.67.5.775
    Language: Unknown
    Publisher: American Veterinary Medical Association (AVMA)
    Publication Date: 2006
    detail.hit.zdb_id: 2056942-7
    SSG: 22
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Phylogenetic Relationships of Monocots Based on the Highly Informative Plastid Gene ndhF
    Claremont Colleges Library ; 2006
    In:  Aliso Vol. 22, No. 1 ( 2006), p. 28-51
    Details
    In: Aliso, Claremont Colleges Library, Vol. 22, No. 1 ( 2006), p. 28-51
    Type of Medium: Online Resource
    ISSN: 2327-2929
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.5642/aliso.20062201
    DOI: 10.5642/aliso
    DOI: 10.5642/aliso.20062201.04
    Language: Unknown
    Publisher: Claremont Colleges Library
    Publication Date: 2006
    detail.hit.zdb_id: 2912703-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...