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  • 1
    Online Resource
    Online Resource
    Could there be a pathogenetic association between Ventricular Septal Defect (VSD) and Acute Lymphoblastic Leukaemia (ALL)? A case report from health-resource poor setting
    Nigerian Medical Association Sokoto State Branch ; 2020
    In:  Annals of Basic and Medical Sciences Vol. 1, No. 1 ( 2020-12-31)
    Details
    In: Annals of Basic and Medical Sciences, Nigerian Medical Association Sokoto State Branch, Vol. 1, No. 1 ( 2020-12-31)
    Abstract: Both Ventricular Septal Defect (VSD) and Acute Lymphoblastic Leukaemia (ALL) are relatively common in childhood. While the former is congenital, the latter is usually acquired. Diagnosis and thorough profiling of patient with ALL remains a great challenge in most resource poor settings including our hospital. Despite the high prevalence of these conditions in our environment, there is no previously reported case of the two coexisting in an individual based on our literature search. We report a ten-year old boy in whom ALL unmasked the diagnosis of VSD and non-availability of diagnostic facilities prevented exploring any possible pathogenetic relationship between the two conditions in case of its existence.
    Type of Medium: Online Resource
    ISSN: 2782-7550 , 2782-7542
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.51658/ABMS.202011
    DOI: 10.51658/ABMS
    DOI: 10.51658/ABMS.202011.8
    Language: Unknown
    Publisher: Nigerian Medical Association Sokoto State Branch
    Publication Date: 2020
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  • 2
    Online Resource
    Online Resource
    Estimation of water quality index using artificial intelligence approaches and multi-linear regression
    Institute of Advanced Engineering and Science ; 2020
    In:  IAES International Journal of Artificial Intelligence (IJ-AI) Vol. 9, No. 1 ( 2020-03-01), p. 126-
    Details
    In: IAES International Journal of Artificial Intelligence (IJ-AI), Institute of Advanced Engineering and Science, Vol. 9, No. 1 ( 2020-03-01), p. 126-
    Abstract: 〈 span lang="EN-US" 〉 Water quality index is a measure of water quality at a certain location and over a period of time. High value indicates that the water is unsafe for drinking and inadequate in quality to meet the designated uses. Most of the classical models are unreliable producing unpromising forecasting results. This study presents Artificial Intelligence (AI) techniques and a Multi Linear Regression (MLR) as the classical linear model for estimating the Water Quality Index (WQI) of Palla station of Yamuna river, India. Full-scale data of the river were used in validating the models. Performance measures such as Mean Square Error (MSE), Root Mean Squared Error (RMSE) and Determination Coefficient (DC) were utilized in evaluating the accuracy and performance of the models. The obtained result depicted the superiority of AI models over the MLR model. The results also indicated that, the best model of both ANN and ANFIS proved high improvement in performance accuracy over MLR up to 10% in the verification phase. The difference between ANN and ANFIS accuracy is negligible due to a slight increment in performance accuracy indicating that both ANN and ANFIS could serve as reliable models for the estimation of WQI 〈 /span 〉 .
    Type of Medium: Online Resource
    ISSN: 2252-8938 , 2089-4872
    URL: Issue
    URL: Article
    DOI: 10.11591/ijai.v9.i1
    DOI: 10.11591/ijai.v9.i1.pp126-134
    Language: Unknown
    Publisher: Institute of Advanced Engineering and Science
    Publication Date: 2020
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  • 3
    Online Resource
    Online Resource
    Phytochemical Screening and Antibacterial Activity of Stem Bark of Baobab Tree (Adonsonia digitata) on some clinical isolate
    Hibiscus Publisher Enterprise ; 2020
    In:  Journal of Biochemistry, Microbiology and Biotechnology Vol. 8, No. 2 ( 2020-12-28), p. 21-24
    Details
    In: Journal of Biochemistry, Microbiology and Biotechnology, Hibiscus Publisher Enterprise, Vol. 8, No. 2 ( 2020-12-28), p. 21-24
    Abstract: The use of plant and their secondary metabolite for the treatment of several illnesses is gaining attention across the globe. For this reason, baobab tree was procured in order to test its effect on some bacterial isolate. Powdered stem bark of Adansonia digitata was extracted with chloroform and methanol using percolation method of extraction. The extracts were dark brown and reddish brown in color respectively with a gummy texture. The chloroform and methanolic extracts were screened from the presence of secondary metabolites using standard technique. The result of photochemical screening indicated the presence of alkaloid, flavonoid, tannin, reducing sugar and steroid in one or both the extracts. The extracts were further tested, on confirmed clinical isolates of Salmonella typhi and Staphylococcus aureus using disc diffusion method and micro – broth dilution technique. The result of sensitivity test indicated that the tested clinical isolates were more sensitive to chloroform extract than the methanolic extract because larger zones of inhibitions were obtained with chloroform extract. In both methods used, the organisms were susceptible to all extracts even at the lowest concentration of 15 ï­g with zones of inhibitions ranging from (8 – 10 mm).
    Type of Medium: Online Resource
    ISSN: 2289-5779
    URL: Issue
    URL: Article
    DOI: 10.54987/jobimb.v8i2
    DOI: 10.54987/jobimb.v8i2.539
    Language: Unknown
    Publisher: Hibiscus Publisher Enterprise
    Publication Date: 2020
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  • 4
    Online Resource
    Online Resource
    SURVEY OF FABRIC RE-DYEING ACTIVITIES AS A POTENTIAL ENVIRONMENTAL PROBLEM IN URBAN KANO, NIGERIA
    Federal University Dutsin-Ma ; 2020
    In:  FUDMA JOURNAL OF SCIENCES Vol. 4, No. 3 ( 2020-09-23), p. 285-291
    Details
    In: FUDMA JOURNAL OF SCIENCES, Federal University Dutsin-Ma, Vol. 4, No. 3 ( 2020-09-23), p. 285-291
    Abstract: A new re-dyeing practice has emerged and is fast spreading in urban Kano causing damage to the environment. This survey was carried out to assess selected fabric re-dyeing activity sites and their environmental impacts. This was achieved with the aid of designed questionnaire. Nine major dyeing sites in urban Kano: Kofar Mata, Chiranci, Karshen Waya, Rijiyar Zaki, Jan Bulo, Zawaciki, Kofar Na’isa, Karofin Zage and Goron Dutse dyeing pits were surveyed. The result revealed that individuals involved are males within the age range of 14 – 35years. The major sources of water are; pipe borne water, earthen dug wells and motorized borehole pumps. The dye wastewater is usually discharged untreated into street drains, ground surface and constructed pits. Individuals involved use protective measures such as face masks, hand gloves and traditional leather jackets. The dye powders, solutions and other constituents, when in contact with the skin cause serious burns, skin hardening and irritations. Inhalation of the gas emitted by the dye solution causes stomach upset and swelling of the body, which may sometimes be treated traditionally. The dye wastewater also destructs plantations/vegetation and inhibits survival of soil invertebrates such as earthworms. This calls for a general enlightenment to the users and general public on both the environmental and health risks of these substances
    Type of Medium: Online Resource
    ISSN: 2616-1370 , 2645-2944
    URL: Article
    DOI: 10.33003/fjs-2020-0403-393
    Language: Unknown
    Publisher: Federal University Dutsin-Ma
    Publication Date: 2020
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  • 5
    Online Resource
    Online Resource
    Antidepressant-like effects of methanol leaves extract of 〈I〉Leptadenia hastata 〈/I〉(Asclepidiaceae) in mice
    African Journals Online (AJOL) ; 2020
    In:  Bayero Journal of Pure and Applied Sciences Vol. 12, No. 1 ( 2020-04-15), p. 105-111
    Details
    In: Bayero Journal of Pure and Applied Sciences, African Journals Online (AJOL), Vol. 12, No. 1 ( 2020-04-15), p. 105-111
    Abstract: Depression is a serious disorder that affects people in all communities across the world, a major cause of disability and morbidity worldwide. The drugs used in its management are associated with adverse effects and delayed response, hence it’s important to look for antidepressant plants with proven advantages and favourable benefits.  Leptadenia hastata (Pers.) Decne belongs to the family Asclepidiaceae and is widely used in Tropical Africa as a vegetable due to its low toxicity and therapeutic benefits, it is used in the treatment of evil spirit, psychiatric disorders and hallucination. The aim of this study was to evaluate the antidepressant-like effect of the methanol leaves extract of Leptadenia hastata (LHME) and its fractions. Phytochemical screening and acute toxicity (LD50) study were done using standard procedures. Antidepressant-like effects of the LHME and its fractions was evaluated using the tail suspension test (TST) and forced swim test (FST). The intraperitoneal (i.p) median lethal dose was estimated to be 〉 5000 mg/kg. The LHME and Residual aqueous fraction (RAF) at dose 250-1000 mg/kg are significantly (P 〈 0.05) and dose-dependently, while n-butanol fraction (NBF) at 400 mg/kg decreased the duration of immobility in the TST and FST respectively. There was no significant change in the number of squares crossed in the OFT. In conclusion, the L. hastata plant possesses antidepressant-like effects. Keywords: Depression, Forced swim test, Leptadenia hastata, Medicinal plant and Tail suspension test
    Type of Medium: Online Resource
    ISSN: 2006-6996 , 2006-6996
    URL: Article
    DOI: 10.4314/bajopas.v12i1.18S
    Language: Unknown
    Publisher: African Journals Online (AJOL)
    Publication Date: 2020
    detail.hit.zdb_id: 2620376-5
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  • 6
    Online Resource
    Online Resource
    Evaluation of Plants Extracts from Capsicum annum and Allium sativum against Aphis craccivora Attacking Cowpea Plant in Kano, Nigeria
    University of Management and Technology ; 2020
    In:  BioScientific Review Vol. 2, No. 1 ( 2020-03-10)
    Details
    In: BioScientific Review, University of Management and Technology, Vol. 2, No. 1 ( 2020-03-10)
    Abstract: The efficacy of Capsicum annum fruits and Allium sativum cloves methanolic crude extracts were evaluated on field for the control of Aphis craccivora attacking cowpea plants. Two cowpea genotypes (IAR-48 and IT97K-499-35) were planted separately in a randomized block design, for a cowpea genotype an experimental plots measured 5m x 3m with 1.5m space between plots was demarcated. The plot contained four subplots each measured 1.67m x 3m and replicated three times, given the total of twelve subplots. Within a subplot are three pairs of ridges (70cm apart) tallied with the three different concentrations (200, 600 and 1000ppm) for the plant extracts treatments application. Plant extract treatments along side with synthetic chemical insecticide (Magic force) as positive control were applied to the subplots using Knapsack sprayer 15 days after sowing. The results showed that the population scores of A. craccivora after treatments application on susceptible genotype IAR-48 was reduced significantly (p 〈 0.05) when compared with untreated control subplot. The least population scores of this insect on genotype IAR-48 was recorded in plants treated with A. sativum at 600ppm concentration level which was effective over positive control (synthetic chemical). The genotype IT97K-499-35 recorded no population aphid in plants treated with A. sativum at 200ppm concentration level which is also effective over the positive control. There is critical need to enhance the use of plant extracts scientifically on field as part of Integrated Pests Management for safe food production.
    Type of Medium: Online Resource
    ISSN: 2663-4201 , 2663-4198
    URL: Issue
    URL: Article
    DOI: 10.32350/BSR.0201
    DOI: 10.32350/BSR.0201.02
    Language: Unknown
    Publisher: University of Management and Technology
    Publication Date: 2020
    detail.hit.zdb_id: 3041603-6
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  • 7
    Online Resource
    Online Resource
    A Continuing Quest for an Acceptable Alternative Sickle Cell Anaemia (SCA) Severity Scoring System in a Resource-Constrained Setting
    Nigerian Medical Association Sokoto State Branch ; 2020
    In:  Annals of Basic and Medical Sciences Vol. 1, No. 1 ( 2020-12-31)
    Details
    In: Annals of Basic and Medical Sciences, Nigerian Medical Association Sokoto State Branch, Vol. 1, No. 1 ( 2020-12-31)
    Abstract: Background: Sickle cell Anaemia (SCA) severity scoring has remained challenging. Scoring systems based on clinical and certain laboratory parameters are limited in simplicity and wide applicability. This is further worsened by dearth of exhaustive and accurate patient history. This study compared a simple, laboratory parameter-based severity scoring system to a pre-existing scoring system. Methodology: Derivation group (n = 45) and validation group (n = 300) were enrolled during steady state. Complications, haemoglobin (Hb) concentration and white blood cell counts (WBC) were documented. Severity scores were computed for each participant based on number of complications, Hb and WBC counts using a preexisting scoring system. Proposed scoring system
    Type of Medium: Online Resource
    ISSN: 2782-7550 , 2782-7542
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.51658/ABMS.202011
    DOI: 10.51658/ABMS
    DOI: 10.51658/ABMS.202011.5
    Language: Unknown
    Publisher: Nigerian Medical Association Sokoto State Branch
    Publication Date: 2020
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    Online Resource
  • 8
    Online Resource
    Online Resource
    Environmental impact assessment in Nigeria- A review
    GSC Online Press ; 2020
    In:  World Journal of Advanced Research and Reviews Vol. 8, No. 3 ( 2020-12-30), p. 330-336
    Details
    In: World Journal of Advanced Research and Reviews, GSC Online Press, Vol. 8, No. 3 ( 2020-12-30), p. 330-336
    Abstract: Environmental Impact Assessment (EIA) is an essential tool used for decision making in a developmental projects as well as a systematic process to identify, predict and evaluate the environmental effects of the proposed actions and projects; the process is applied prior to major decisions and commitments being made. This paper makes a systematic review of the challenges relating to the application of Environmental Impact Assessment in Nigeria, in order to achieve sustainable development. The present review describes the laws, basic principles, procedures, sustainability and impact of EIA on biological aspect, meanwhile the paper also emphases on the constraints of EIA in Nigeria.
    Type of Medium: Online Resource
    ISSN: 2581-9615
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.30574/wjarr.2020.8.3
    DOI: 10.30574/wjarr
    DOI: 10.30574/wjarr.2020.8.3.0487
    Language: Unknown
    Publisher: GSC Online Press
    Publication Date: 2020
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  • 9
    Online Resource
    Online Resource
    The Topp Leone Kumaraswamy-G Family of Distributions with Applications to Cancer Disease Data
    Knowledge E DMCC ; 2020
    In:  Journal of Biostatistics and Epidemiology ( 2020-11-25)
    Details
    In: Journal of Biostatistics and Epidemiology, Knowledge E DMCC, ( 2020-11-25)
    Abstract: Background: In the last few years, statisticians have introduced new generated families of univariate distributions. These new generators are obtained by adding one or more extra shape parameters to the underlying distribution to get more flexibility in fitting data in different areas such as medical sciences, economics, finance and environmental sciences. The addition of parameter(s) has been proven useful in exploring tail properties and also for improving the goodness-of-fit of the family of distributions under study. Methods: A new three-parameter family of distributions was introduced by using the idea of T-X methodology. Some statistical properties of the new family were derived and studied. Results: A new Topp Leone Kumaraswamy-G family of distributions was introduced. Two special sub-models, that is, the Topp Leone Kumaraswamy exponential distribution and Topp Leone Kumaraswamy log-logistic distribution were investigated. Two real data sets were used to assess the flexibility of the sub-models. Conclusion: The results suggest that the two sub-models performed better than their competitors.
    Type of Medium: Online Resource
    ISSN: 2383-420X , 2383-4196
    URL: Article
    DOI: 10.18502/jbe.v6i1.4758
    Language: Unknown
    Publisher: Knowledge E DMCC
    Publication Date: 2020
    detail.hit.zdb_id: 2806590-6
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  • 10
    Online Resource
    Online Resource
    EVALUATION OF THE IMPACT OF PLASMID CURING ON ANTIBIOTIC RESISTANCE ON SOME CLINICAL ISOLATES OF ESCHERICHIA COLI
    Federal University Dutsin-Ma ; 2020
    In:  FUDMA JOURNAL OF SCIENCES Vol. 4, No. 3 ( 2020-09-24), p. 323-327
    Details
    In: FUDMA JOURNAL OF SCIENCES, Federal University Dutsin-Ma, Vol. 4, No. 3 ( 2020-09-24), p. 323-327
    Abstract: Multidrug resistance (MDR) exhibited by some strains of Escherichia coli may be due to acquiring mobile genetic element (R-plasmid) by the bacteria, or intrinsically induced by inappropriate use of antibiotics by the hosts.  Infection by such strains may result to prolonged illness and greater risk of death. The study evaluated the impact of curing on antibiotic resistance on selected clinical isolates of E. coli. Twenty clinical isolates of E. coli from our previous studies were re-characterized using conventional microbiological techniques. Antibiotic sensitivity testing was determined by disk diffusion method, MDR selected based on resistance to ≥ 2 classes of antibiotics. Multiple antibiotic resistance (MAR) index was determined as ratio of the number of antibiotic resisted to the total number of antibiotics tested and considered significant if ≥. 0.2. The isolates that showed significant MAR index were subjected to plasmid curing using acridine orange, thereafter, profiled for plasmid and the cured ones were re-tested against the antibiotics they initially resisted. Out of the 20 isolates, 19 (95%) were confirmed as E. coli, all (100%) of which were MDRs, which was highest against augmentin (78.9%) followed by amoxacillin (52.6%). However, after the plasmid curing only 6 (31.6%) out of the 19 isolates cured retained significant MAR index and the level of the significance had reduced drastically in 16 (84.2%) isolates. Conclusively, curing assay can completely eliminate R-plasmid acquired resistance. More studied on plasmid curing agents for possible augmentation of the agents into antibiotics may see the rise of successful antibiotic era again.
    Type of Medium: Online Resource
    ISSN: 2616-1370 , 2645-2944
    URL: Article
    DOI: 10.33003/fjs-2020-0403-335
    Language: Unknown
    Publisher: Federal University Dutsin-Ma
    Publication Date: 2020
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