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  • 1
    Online Resource
    Online Resource
    African Journals Online (AJOL) ; 2023
    In:  Tropical Journal of Pharmaceutical Research Vol. 22, No. 2 ( 2023-06-12), p. 343-348
    In: Tropical Journal of Pharmaceutical Research, African Journals Online (AJOL), Vol. 22, No. 2 ( 2023-06-12), p. 343-348
    Abstract: Purpose: To investigate the effect of adipose-derived stem cells (ADSCs) on the survival rate of long random pattern skin flaps in rats and the likely underlying mechanism. Methods: Twenty (20) SPF-grade SD rats were randomly divided into control group and study group, with 10 rats in each group. Rats in the control group were given phosphate buffered saline (PBS), while rats in the study group received ADSCs. The survival rate of the skin flaps was compared between the 2 groups on day 7 after operation, while the levels of indices related to oxidative stress and inflammatory response were compared on the 7th and 14th days after operation. Results: Necrosis in the study group was milder (p 〈 0.05). On the 7th post-operation day, the survival rate of rat skin flap in the study group was significantly higher than that in the control group (p 〈 0.05), but the MDA level in the study group was lower than that of the control group (p 〈 0.05). On the 14th day after the operation, the MDA level was decreased in the two groups (p 〈 0.05), with a lower MDA level in the study group than in the control group (p 〈 0.05). Conclusion: ADSCs inhibit inflammatory response and reduces the level of oxidative stress after long random pattern skin flap transplantation in rats, thereby enhancing blood supply to the flap transplantation area and improving its survival rate. Thus, ADSCs have a potential clinical application in enhancing blood supply in skin transplantation.
    Type of Medium: Online Resource
    ISSN: 1596-9827 , 1596-5996
    Language: Unknown
    Publisher: African Journals Online (AJOL)
    Publication Date: 2023
    detail.hit.zdb_id: 2125881-8
    SSG: 15,3
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  • 2
    In: Frontiers in Plant Science, Frontiers Media SA, Vol. 9 ( 2018-12-14)
    Type of Medium: Online Resource
    ISSN: 1664-462X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2018
    detail.hit.zdb_id: 2687947-5
    detail.hit.zdb_id: 2613694-6
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  • 3
    Online Resource
    Online Resource
    Vilnius Gediminas Technical University ; 2021
    In:  JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT Vol. 27, No. 2 ( 2021-02-10), p. 76-86
    In: JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT, Vilnius Gediminas Technical University, Vol. 27, No. 2 ( 2021-02-10), p. 76-86
    Abstract: Worldwide water scarcity has prompted governments to develop alternative water resources, and public acceptance plays a critical role in the implementation of recycled water projects. The aim of this study was to explore how public acceptance can be affected by people’s emotional responses to recycled water. In study 1, the general population was divided into four groups, clustering analysis with the intensity of various emotions was conducted, and the association between emotions and acceptance was explored. In study 2, the emotions, people’s acceptance, and “objects of care” of water treatment experts were compared with those of members of the general population for further study. We found that the objects of care shortened the psychological distance between individuals and recycled water, which led people to generate specific emotions to recycled water. In a broader context, the study suggested that various emotions motivate people’s behavior to accept or oppose the use of recycled water.
    Type of Medium: Online Resource
    ISSN: 1392-3730 , 1822-3605
    Language: Unknown
    Publisher: Vilnius Gediminas Technical University
    Publication Date: 2021
    detail.hit.zdb_id: 2571620-7
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  • 4
    In: Frontiers in Surgery, Frontiers Media SA, Vol. 9 ( 2022-10-26)
    Abstract: As neoadjuvant chemotherapy is widely used in breast cancer patients, the lymph node ratio has not been fully validated as a prognostic indicator of breast cancer received neoadjuvant chemotherapy. This study was conducted to investigate the prognostic value of lymph node ratio in breast cancer patients received neoadjuvant chemotherapy. Methods Systematic searches were performed in the PubMed, Embase, and Cochrane Library databases until 15 December 2021 for studies on the association between lymph node ratio and the prognosis of breast cancer after neoadjuvant chemotherapy. Overall survival and disease-free survival were used as outcome events, and hazard ratio was chosen as the parameter to evaluate the correlation. The dose-response relationship was assessed by restricted cubic splines. In the subgroup analyses, which were used to explore potential heterogeneity among the included studies according to study region and sample size. Sensitivity analysis was performed to assess the stability of individual studies, and publication bias was determined with funnel plots, Begg’s test, and Egger & amp;apos;s test. All statistical analyses were performed using Stata 15.1. Results A total of 12 studies with 4,864 patients were included in this meta-analysis. In this study, high lymph node ratio was significantly associated with decreased overall survival (HR: 4.74; 95%CI: 3.36–6.67; P  & lt; 0.001) and disease-free survival (HR: 4.77; 95%CI: 3.69–6.17; P  & lt; 0.001). Moreover, the dose-response meta-analysis showed a linear association between higher lymph node ratio and shorter overall survival and disease-free survival in breast cancer patients after neoadjuvant chemotherapy. Conclusions The meta-analysis suggested that high lymph node ratio was significantly associated with short overall survival and disease-free survival in breast cancer patients after neoadjuvant chemotherapy. Therefore, lymph node ratio is an independent predictive factor for the prognosis of breast cancer patients after neoadjuvant chemotherapy, which may better refine the cancer staging system.
    Type of Medium: Online Resource
    ISSN: 2296-875X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2773823-1
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