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  • 1
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    Data_Sheet_2.docx
    Frontiers Media SA ; 2022
    In:  Frontiers in Public Health Vol. 10 ( 2022-6-21)
    Details
    In: Frontiers in Public Health, Frontiers Media SA, Vol. 10 ( 2022-6-21)
    Abstract: To quantify the burden and variation trends of cancers in children under 5 years at the global, regional, and national levels from 1990 to 2019. Methods Epidemiological data for children under 5 years who were diagnosed with any one childhood cancer were obtained from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) from 1990 to 2019. The outcomes were the absolute numbers and rates of incidence, prevalence, mortality, and disability-adjusted life-years (DALYs) for different types of cancer. Results In 2019, 8,774,979.1 incident cases (95% uncertainty interval [UI]: 6,243,599.2 to11,737,568.5) and 8,956,583.8 (6,446,323.9 to 12,364,520.8) prevalent cases of cancer in children under 5 years were identified worldwide; these cancers resulted in 44,451.6 (36,198.7 to 53,905.9) deaths and 3,918,014.8 (3,196,454.9 to 4,751,304.2) DALYs. From 1990 to 2019, although the numbers of incident and prevalent cases only decreased by −4.6% (−7.0 to −2.2) and −8.3% (−12.6 to −3.4), respectively, the numbers of deaths and DALYs clearly declined by −47.8% (−60.7 to −26.4) and −47.7% (−60.7 to −26.2), respectively. In 2019, the middle sociodemographic index (SDI) regions had the highest incidence and prevalence, whereas the low SDI regions had the most mortality and DALYs. Although all of the SDI regions displayed a steady drop in deaths and DALYs between 1990 and 2019, the low-middle and low SDI regions showed increasing trends of incidence and prevalence. Leukemia remained the most common cancer globally in 2019. From 1990 to 2019, the burdens of leukemia, liver cancer, and Hodgkin's lymphoma declined, whereas the incidence and prevalence of other cancers grew, particularly testicular cancer. Conclusions The global childhood cancer burden in young children has been steadily decreasing over the past three decades. However, the burdens and other characteristics have varied across different regions and types of cancers. This highlights the need to reorient current treatment strategies and establish effective prevention methods to reduce the global burden of childhood cancer.
    Type of Medium: Online Resource
    ISSN: 2296-2565
    URL: Article
    URL: Article
    URL: Article
    DOI: 10.3389/fpubh.2022.910641
    DOI: 10.3389/fpubh.2022.910641.s001
    DOI: 10.3389/fpubh.2022.910641.s002
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2711781-9
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  • 2
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    Consensus on the digestive endoscopic tunnel technique
    Baishideng Publishing Group Inc. ; 2019
    In:  World Journal of Gastroenterology Vol. 25, No. 7 ( 2019-2-21), p. 744-776
    Details
    In: World Journal of Gastroenterology, Baishideng Publishing Group Inc., Vol. 25, No. 7 ( 2019-2-21), p. 744-776
    Type of Medium: Online Resource
    ISSN: 1007-9327
    URL: Article
    DOI: 10.3748/wjg.v25.i7.744
    Language: Unknown
    Publisher: Baishideng Publishing Group Inc.
    Publication Date: 2019
    detail.hit.zdb_id: 2084831-6
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  • 3
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    First Sagittarius A* Event Horizon Telescope Results. I. The Shadow of the Supermassive Black Hole in the Center of the Milky Way
    American Astronomical Society ; 2022
    In:  The Astrophysical Journal Letters Vol. 930, No. 2 ( 2022-05-01), p. L12-
    Details
    In: The Astrophysical Journal Letters, American Astronomical Society, Vol. 930, No. 2 ( 2022-05-01), p. L12-
    Abstract: We present the first Event Horizon Telescope (EHT) observations of Sagittarius A* (Sgr A*), the Galactic center source associated with a supermassive black hole. These observations were conducted in 2017 using a global interferometric array of eight telescopes operating at a wavelength of λ = 1.3 mm. The EHT data resolve a compact emission region with intrahour variability. A variety of imaging and modeling analyses all support an image that is dominated by a bright, thick ring with a diameter of 51.8 ± 2.3 μ as (68% credible interval). The ring has modest azimuthal brightness asymmetry and a comparatively dim interior. Using a large suite of numerical simulations, we demonstrate that the EHT images of Sgr A* are consistent with the expected appearance of a Kerr black hole with mass ∼4 × 10 6 M ⊙ , which is inferred to exist at this location based on previous infrared observations of individual stellar orbits, as well as maser proper-motion studies. Our model comparisons disfavor scenarios where the black hole is viewed at high inclination ( i 〉 50°), as well as nonspinning black holes and those with retrograde accretion disks. Our results provide direct evidence for the presence of a supermassive black hole at the center of the Milky Way, and for the first time we connect the predictions from dynamical measurements of stellar orbits on scales of 10 3 –10 5 gravitational radii to event-horizon-scale images and variability. Furthermore, a comparison with the EHT results for the supermassive black hole M87* shows consistency with the predictions of general relativity spanning over three orders of magnitude in central mass.
    Type of Medium: Online Resource
    ISSN: 2041-8205 , 2041-8213
    URL: Article
    DOI: 10.3847/2041-8213/ac6674
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2022
    detail.hit.zdb_id: 2207648-7
    detail.hit.zdb_id: 2006858-X
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  • 4
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    Optimization of optical control of nitrogen vacancy centers in solid diamond
    Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences ; 2020
    In:  Acta Physica Sinica Vol. 69, No. 14 ( 2020), p. 147601-
    Details
    In: Acta Physica Sinica, Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences, Vol. 69, No. 14 ( 2020), p. 147601-
    Abstract: The nitrogen-vacancy (NV) centers in diamond have the advantages of stable triaxial structure, ultra-long electron spin coherence time and simple optical readout at room temperature. A nitrogen atom in the diamond crystal replaces a carbon atom and a vacancy is generated at the adjacent position, forming a point defect in the 〈i〉C〈/i〉〈sub〉3〈i〉v〈/i〉〈/sub〉 space group structure. Its ground state and excited state are both spin triplet states. It is the key to achieving efficient preparation of optical initial state and extracting NV color center’s information in the researches of highly sensitive sensing magnetic detection, temperature detection, biological imaging, quantum computing, etc. However, there was no systematic study on relevant parameters of laser for high-concentration NV color center’s samples in previous experimental studies. Based on a high concentration diamond NV ensemble, we use pulsed optical detection magnetic resonance (ODMR) technology to systematically study the relationship among laser initial polarization time, information reading time and laser power, and the influence of laser incident polarization angle on the accuracy of sensing information. The effects of various laser parameters on the NV1 peak of ODMR on the [111] axis of the NVs of diamond are also investigated. The contrast of ODMR increases firstly with a sigmoid function and then decreases with an e-exponential function as the information reading time increases. The incident polarization angle of the laser is sinusoidal, with a period of 90°. According to the above experimental results, we finally choose the appropriate experimental parameters at 45.8 W/cm〈sup〉2〈/sup〉 (300 μs of polarization, 700 ns, reading time, laser incident angle is 220°) for ODMR test. Compared with previous experimental parameters (polarization time was 50 us, read the time of 3000 ns, laser incident angle was 250°), the experimental results show that the contrast of ODMR increases from 2.1% to 4.6%, and the typical magnetic sensitivity is improved from 21.6 nT/Hz〈sup〉1/2〈/sup〉 to 5.6 nT/Hz〈sup〉1/2〈/sup〉. The optimization of the optical control of NVs in solid diamond is realized. The above results provide an effective support for the detection of high-sensitivity manipulation sensing based on high-concentration NV ensemble.
    Type of Medium: Online Resource
    ISSN: 1000-3290 , 1000-3290
    URL: Journal
    URL: Article
    DOI: 10.7498/aps
    DOI: 10.7498/aps.69.20200072
    Language: Unknown
    Publisher: Acta Physica Sinica, Chinese Physical Society and Institute of Physics, Chinese Academy of Sciences
    Publication Date: 2020
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  • 5
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    First M87 Event Horizon Telescope Results. VII. Polarization of the Ring
    American Astronomical Society ; 2021
    In:  The Astrophysical Journal Letters Vol. 910, No. 1 ( 2021-03-01), p. L12-
    Details
    In: The Astrophysical Journal Letters, American Astronomical Society, Vol. 910, No. 1 ( 2021-03-01), p. L12-
    Abstract: In 2017 April, the Event Horizon Telescope (EHT) observed the near-horizon region around the supermassive black hole at the core of the M87 galaxy. These 1.3 mm wavelength observations revealed a compact asymmetric ring-like source morphology. This structure originates from synchrotron emission produced by relativistic plasma located in the immediate vicinity of the black hole. Here we present the corresponding linear-polarimetric EHT images of the center of M87. We find that only a part of the ring is significantly polarized. The resolved fractional linear polarization has a maximum located in the southwest part of the ring, where it rises to the level of ∼15%. The polarization position angles are arranged in a nearly azimuthal pattern. We perform quantitative measurements of relevant polarimetric properties of the compact emission and find evidence for the temporal evolution of the polarized source structure over one week of EHT observations. The details of the polarimetric data reduction and calibration methodology are provided. We carry out the data analysis using multiple independent imaging and modeling techniques, each of which is validated against a suite of synthetic data sets. The gross polarimetric structure and its apparent evolution with time are insensitive to the method used to reconstruct the image. These polarimetric images carry information about the structure of the magnetic fields responsible for the synchrotron emission. Their physical interpretation is discussed in an accompanying publication.
    Type of Medium: Online Resource
    ISSN: 2041-8205 , 2041-8213
    URL: Article
    DOI: 10.3847/2041-8213/abe71d
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2021
    detail.hit.zdb_id: 2207648-7
    detail.hit.zdb_id: 2006858-X
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  • 6
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    The Variability of the Black Hole Image in M87 at the Dynamical Timescale
    American Astronomical Society ; 2022
    In:  The Astrophysical Journal Vol. 925, No. 1 ( 2022-01-01), p. 13-
    Details
    In: The Astrophysical Journal, American Astronomical Society, Vol. 925, No. 1 ( 2022-01-01), p. 13-
    Abstract: The black hole images obtained with the Event Horizon Telescope (EHT) are expected to be variable at the dynamical timescale near their horizons. For the black hole at the center of the M87 galaxy, this timescale (5–61 days) is comparable to the 6 day extent of the 2017 EHT observations. Closure phases along baseline triangles are robust interferometric observables that are sensitive to the expected structural changes of the images but are free of station-based atmospheric and instrumental errors. We explored the day-to-day variability in closure-phase measurements on all six linearly independent nontrivial baseline triangles that can be formed from the 2017 observations. We showed that three triangles exhibit very low day-to-day variability, with a dispersion of ∼3°–5°. The only triangles that exhibit substantially higher variability (∼90°–180°) are the ones with baselines that cross the visibility amplitude minima on the u – v plane, as expected from theoretical modeling. We used two sets of general relativistic magnetohydrodynamic simulations to explore the dependence of the predicted variability on various black hole and accretion-flow parameters. We found that changing the magnetic field configuration, electron temperature model, or black hole spin has a marginal effect on the model consistency with the observed level of variability. On the other hand, the most discriminating image characteristic of models is the fractional width of the bright ring of emission. Models that best reproduce the observed small level of variability are characterized by thin ring-like images with structures dominated by gravitational lensing effects and thus least affected by turbulence in the accreting plasmas.
    Type of Medium: Online Resource
    ISSN: 0004-637X , 1538-4357
    URL: Article
    DOI: 10.3847/1538-4357/ac332e
    RVK:
    UA 1000
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2022
    detail.hit.zdb_id: 2207648-7
    detail.hit.zdb_id: 1473835-1
    SSG: 16,12
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  • 7
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    Selective Dynamical Imaging of Interferometric Data
    American Astronomical Society ; 2022
    In:  The Astrophysical Journal Letters Vol. 930, No. 2 ( 2022-05-01), p. L18-
    Details
    In: The Astrophysical Journal Letters, American Astronomical Society, Vol. 930, No. 2 ( 2022-05-01), p. L18-
    Abstract: Recent developments in very long baseline interferometry (VLBI) have made it possible for the Event Horizon Telescope (EHT) to resolve the innermost accretion flows of the largest supermassive black holes on the sky. The sparse nature of the EHT’s ( u , v )-coverage presents a challenge when attempting to resolve highly time-variable sources. We demonstrate that the changing ( u , v )-coverage of the EHT can contain regions of time over the course of a single observation that facilitate dynamical imaging. These optimal time regions typically have projected baseline distributions that are approximately angularly isotropic and radially homogeneous. We derive a metric of coverage quality based on baseline isotropy and density that is capable of ranking array configurations by their ability to produce accurate dynamical reconstructions. We compare this metric to existing metrics in the literature and investigate their utility by performing dynamical reconstructions on synthetic data from simulated EHT observations of sources with simple orbital variability. We then use these results to make recommendations for imaging the 2017 EHT Sgr A* data set.
    Type of Medium: Online Resource
    ISSN: 2041-8205 , 2041-8213
    URL: Article
    DOI: 10.3847/2041-8213/ac6615
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2022
    detail.hit.zdb_id: 2207648-7
    detail.hit.zdb_id: 2006858-X
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  • 8
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    Polarimetric Properties of Event Horizon Telescope Targets from ALMA
    American Astronomical Society ; 2021
    In:  The Astrophysical Journal Letters Vol. 910, No. 1 ( 2021-03-01), p. L14-
    Details
    In: The Astrophysical Journal Letters, American Astronomical Society, Vol. 910, No. 1 ( 2021-03-01), p. L14-
    Abstract: We present the results from a full polarization study carried out with the Atacama Large Millimeter/submillimeter Array (ALMA) during the first Very Long Baseline Interferometry (VLBI) campaign, which was conducted in 2017 April in the λ 3 mm and λ 1.3 mm bands, in concert with the Global mm-VLBI Array (GMVA) and the Event Horizon Telescope (EHT), respectively. We determine the polarization and Faraday properties of all VLBI targets, including Sgr A*, M87, and a dozen radio-loud active galactic nuclei (AGNs), in the two bands at several epochs in a time window of 10 days. We detect high linear polarization fractions (2%–15%) and large rotation measures (RM 〉 10 3.3 –10 5.5 rad m −2 ), confirming the trends of previous AGN studies at millimeter wavelengths. We find that blazars are more strongly polarized than other AGNs in the sample, while exhibiting (on average) order-of-magnitude lower RM values, consistent with the AGN viewing angle unification scheme. For Sgr A* we report a mean RM of (−4.2 ± 0.3) × 10 5 rad m −2 at 1.3 mm, consistent with measurements over the past decade and, for the first time, an RM of (–2.1 ± 0.1) × 10 5 rad m −2 at 3 mm, suggesting that about half of the Faraday rotation at 1.3 mm may occur between the 3 mm photosphere and the 1.3 mm source. We also report the first unambiguous measurement of RM toward the M87 nucleus at millimeter wavelengths, which undergoes significant changes in magnitude and sign reversals on a one year timescale, spanning the range from −1.2 to 0.3 × 10 5 rad m −2 at 3 mm and −4.1 to 1.5 × 10 5 rad m −2 at 1.3 mm. Given this time variability, we argue that, unlike the case of Sgr A*, the RM in M87 does not provide an accurate estimate of the mass accretion rate onto the black hole. We put forward a two-component model, comprised of a variable compact region and a static extended region, that can simultaneously explain the polarimetric properties observed by both the EHT (on horizon scales) and ALMA (which observes the combined emission from both components). These measurements provide critical constraints for the calibration, analysis, and interpretation of simultaneously obtained VLBI data with the EHT and GMVA.
    Type of Medium: Online Resource
    ISSN: 2041-8205 , 2041-8213
    URL: Article
    DOI: 10.3847/2041-8213/abee6a
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2021
    detail.hit.zdb_id: 2207648-7
    detail.hit.zdb_id: 2006858-X
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  • 9
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    Broadband Multi-wavelength Properties of M87 during the 2017 Event Horizon Telescope Campaign
    American Astronomical Society ; 2021
    In:  The Astrophysical Journal Letters Vol. 911, No. 1 ( 2021-04-01), p. L11-
    Details
    In: The Astrophysical Journal Letters, American Astronomical Society, Vol. 911, No. 1 ( 2021-04-01), p. L11-
    Abstract: In 2017, the Event Horizon Telescope (EHT) Collaboration succeeded in capturing the first direct image of the center of the M87 galaxy. The asymmetric ring morphology and size are consistent with theoretical expectations for a weakly accreting supermassive black hole of mass ∼6.5 × 10 9 M ⊙ . The EHTC also partnered with several international facilities in space and on the ground, to arrange an extensive, quasi-simultaneous multi-wavelength campaign. This Letter presents the results and analysis of this campaign, as well as the multi-wavelength data as a legacy data repository. We captured M87 in a historically low state, and the core flux dominates over HST-1 at high energies, making it possible to combine core flux constraints with the more spatially precise very long baseline interferometry data. We present the most complete simultaneous multi-wavelength spectrum of the active nucleus to date, and discuss the complexity and caveats of combining data from different spatial scales into one broadband spectrum. We apply two heuristic, isotropic leptonic single-zone models to provide insight into the basic source properties, but conclude that a structured jet is necessary to explain M87’s spectrum. We can exclude that the simultaneous γ -ray emission is produced via inverse Compton emission in the same region producing the EHT mm-band emission, and further conclude that the γ -rays can only be produced in the inner jets (inward of HST-1) if there are strongly particle-dominated regions. Direct synchrotron emission from accelerated protons and secondaries cannot yet be excluded.
    Type of Medium: Online Resource
    ISSN: 2041-8205 , 2041-8213
    URL: Article
    DOI: 10.3847/2041-8213/abef71
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2021
    detail.hit.zdb_id: 2207648-7
    detail.hit.zdb_id: 2006858-X
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  • 10
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    First M87 Event Horizon Telescope Results. VIII. Magnetic Field Structure near The Event Horizon
    American Astronomical Society ; 2021
    In:  The Astrophysical Journal Letters Vol. 910, No. 1 ( 2021-03-01), p. L13-
    Details
    In: The Astrophysical Journal Letters, American Astronomical Society, Vol. 910, No. 1 ( 2021-03-01), p. L13-
    Abstract: Event Horizon Telescope (EHT) observations at 230 GHz have now imaged polarized emission around the supermassive black hole in M87 on event-horizon scales. This polarized synchrotron radiation probes the structure of magnetic fields and the plasma properties near the black hole. Here we compare the resolved polarization structure observed by the EHT, along with simultaneous unresolved observations with the Atacama Large Millimeter/submillimeter Array, to expectations from theoretical models. The low fractional linear polarization in the resolved image suggests that the polarization is scrambled on scales smaller than the EHT beam, which we attribute to Faraday rotation internal to the emission region. We estimate the average density n e ∼ 10 4–7 cm −3 , magnetic field strength B ∼ 1–30 G, and electron temperature T e ∼ (1–12) × 10 10 K of the radiating plasma in a simple one-zone emission model. We show that the net azimuthal linear polarization pattern may result from organized, poloidal magnetic fields in the emission region. In a quantitative comparison with a large library of simulated polarimetric images from general relativistic magnetohydrodynamic (GRMHD) simulations, we identify a subset of physical models that can explain critical features of the polarimetric EHT observations while producing a relativistic jet of sufficient power. The consistent GRMHD models are all of magnetically arrested accretion disks, where near-horizon magnetic fields are dynamically important. We use the models to infer a mass accretion rate onto the black hole in M87 of (3–20) × 10 −4 M ⊙ yr −1 .
    Type of Medium: Online Resource
    ISSN: 2041-8205 , 2041-8213
    URL: Article
    DOI: 10.3847/2041-8213/abe4de
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2021
    detail.hit.zdb_id: 2207648-7
    detail.hit.zdb_id: 2006858-X
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