In:
International Journal of Ophthalmology, Press of International Journal of Ophthalmology (IJO Press), Vol. 15, No. 2 ( 2022-2-18), p. 213-220
Abstract:
AIM: To explore the effects of laser-activated remote phosphors (LARP) on visual function in guinea pigs.
METHODS: Electroretinogram (ERG) of guinea pigs were observed after LARP irradiation at different frequencies and irradiation times. We evaluated the expression of rhodopsin, β-catenin, connexin36, calretinin, and calbindin in the retina of guinea pigs and measured the density of photoreceptor cells after high-frequency LARP irradiation. RESULTS: After LARP irradiation, the ERG results showed that the amplitude of the dark-adapted 3.0 b-wave of the model eye was lower than that of the control eye after high-frequency irradiation (P & #x0026;#x003C;0.05). The expression of rhodopsin, β-catenin, connexin36, calretinin, and calbindin in the retina of guinea pig declined.
CONCLUSION: There is frequency cumulative damage effect on the retina that relates to LARP illumination frequency. This has significance for staff visual protection policies under LARP lighting conditions.
Type of Medium:
Online Resource
ISSN:
2222-3959
,
2227-4898
DOI:
10.18240/ijo.2022.02.04
Language:
Unknown
Publisher:
Press of International Journal of Ophthalmology (IJO Press)
Publication Date:
2022
detail.hit.zdb_id:
2663246-9
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