In:
Natural Product Communications, SAGE Publications, Vol. 11, No. 2 ( 2016-02), p. 1934578X1601100-
Abstract:
Twenty-eight new phrymarolin derivatives, including twenty-one ethers, six esters and a dehydroxy phrymarolin, were prepared from phrymarolin I and the structures of all the derivatives were confirmed by 1 H NMR and 13 C NMR spectroscopic and MS data analyses. Larvicidal activities of these phrymarolin analogues were assayed against 4 th instar larvae of Culex pipiens pallens. The ester derivatives of phrymarolin showed lower larvicidal activity than phrymarolin I, but some of the ether derivatives and dehydroxy phrymarolin showed much higher activity. Two ether derivatives, 1–18 and 1–19, showed significant larvicidal activity with LC 50 values of 1.89 and 7.78 mg/L, respectively.
Type of Medium:
Online Resource
ISSN:
1934-578X
,
1555-9475
DOI:
10.1177/1934578X1601100225
Language:
English
Publisher:
SAGE Publications
Publication Date:
2016
detail.hit.zdb_id:
2430442-6
SSG:
15,3
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