In:
Natural Product Communications, SAGE Publications, Vol. 7, No. 4 ( 2012-04), p. 1934578X1200700-
Abstract:
Four new eremophilane-type sesquiterpenes, culcitiolides A-D, were isolated from the stem of Senecio culcitioides Sch. Bip (Asteraceae). Their structures were established by detailed 2D NMR spectroscopic and single-crystal X-ray experiments. These compounds were assessed for inhibitory activity against nuclear factor κB (NF-κB). Culcitiolides C and D at 20 μM showed 97 and 100% inhibition of NF-κB activity, respectively.
Type of Medium:
Online Resource
ISSN:
1934-578X
,
1555-9475
DOI:
10.1177/1934578X1200700403
Language:
English
Publisher:
SAGE Publications
Publication Date:
2012
detail.hit.zdb_id:
2430442-6
SSG:
15,3
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