In:
Alimentary Pharmacology & Therapeutics, Wiley, Vol. 35, No. 5 ( 2012-03), p. 552-561
Abstract:
Functional dyspepsia ( FD ) is a common disease without an established optimal treatment. Aim To determine (i) the effect of acupuncture in relieving FD symptoms and improving life quality; (ii) the effect difference between acupoint and non‐acupoint; and (iii) the effect difference among different acupoints. Methods A total of 712 eligible patients were included and randomly assigned to six groups (Group A : specific acupoints of the stomach meridian; Group B : non‐specific acupoints of the stomach meridian; Group C : specific acupoints of alarm and transport points; Group D : specific acupoints of the gallbladder meridian; Group E : sham acupuncture of non‐acupoints; and Group F : itopride). A treatment period of 4 weeks (continuous five sessions per week), and a follow‐up period of 12 weeks were arranged. The outcomes were the (i) patients’ response, (ii) symptoms improvement measured using the S ymptom I ndex of D yspepsia and (iii) quality‐of‐life improvement based on N epean D yspepsia I ndex. Results All groups had an improvement in dyspepsia symptoms and the Q o L at the end of treatment, and the improvement was sustained for 4 weeks and 12 weeks. The overall response rate was significantly higher in acupuncture group A (70.69%), and lower in sham acupuncture group (34.75%), compared with itopride and other acupuncture groups. Similarly, the difference in symptoms and Q o L improvement was significant between group A and the other acupuncture groups. Conclusions Acupuncture is effective in the treatment of functional dyspepsia, and is superior to non‐acupoint puncture. The benefit of acupuncture relies on acupoint specificity.
Type of Medium:
Online Resource
ISSN:
0269-2813
,
1365-2036
DOI:
10.1111/apt.2012.35.issue-5
DOI:
10.1111/j.1365-2036.2011.04979.x
Language:
English
Publisher:
Wiley
Publication Date:
2012
detail.hit.zdb_id:
2003094-0
SSG:
15,3
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