In:
Natural Product Communications, SAGE Publications, Vol. 7, No. 2 ( 2012-02), p. 1934578X1200700-
Abstract:
From the MeOH extract of the heartwood of Artocapus altilis, thirteen phenolic compounds have been isolated, namely curcumin (1), desmethoxycurcumin (2), retrodihydrochalcone (3), apigenin (4), tangeretin (5), nobiletin (6), O-methyldehydrodieugenol (7), dehydrodieugenol (8), β-hydroxypropiovanillone (9), p-coumaric acid (10), p-hydroxybenzaldehyde (11), vanillin (12), and vanillic acid (13). This is the first report on the presence of these compounds in the heartwood of A. altilis. Compounds 1, 2, and 10 showed more potent tyrosinase inhibitory activities, with IC 50 values ranging from 2.3 to 42.0 μM, than the positive control kojic acid (IC 50 , 44.6 μM). The most active compound, p-coumaric acid (10) (IC 50 , 2.3 μM), was 22 times more active in tyrosinase inhibitory activity than kojic acid.
Type of Medium:
Online Resource
ISSN:
1934-578X
,
1555-9475
DOI:
10.1177/1934578X1200700214
Language:
English
Publisher:
SAGE Publications
Publication Date:
2012
detail.hit.zdb_id:
2430442-6
SSG:
15,3
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