Publikationsdatum:
2018-09-25
Beschreibung:
Infection perturbs Bach2- and Bach1-dependent erythroid lineage ‘choice’ to cause anemia Infection perturbs Bach2- and Bach1-dependent erythroid lineage ‘choice’ to cause anemia, Published online: 24 September 2018; doi:10.1038/s41590-018-0202-3 Environmental cues instruct cell fate during hematopoiesis. Igarashi and colleagues show that the transcription factors Bach1 and Bach2 promote erythropoiesis and suppress myelopoiesis. Infection and inflammatory signals suppress Bach expression, which results in anemia.
Print ISSN:
1529-2908
Digitale ISSN:
1529-2916
Thema:
Biologie
,
Medizin
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