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  • 1
    In: Audiology and Neurotology, S. Karger AG, Vol. 17, No. 2 ( 2012), p. 112-120
    Abstract: 〈 i 〉 Objectives: 〈 /i 〉 Repetitive transcranial magnetic stimulation (rTMS), a noninvasive method for altering cortical excitability, is becoming a therapeutic strategy in auditory research institutions worldwide. Application of inhibiting rTMS on these overactive cortical regions can result in effective tinnitus suppression. The aim of this study is to investigate the efficacy of theta-burst rTMS in patients with chronic tinnitus. 〈 i 〉 Study Design: 〈 /i 〉 Parallel randomized control study. 〈 i 〉 Setting: 〈 /i 〉 Tertiary referral center. 〈 i 〉 Patients: 〈 /i 〉 We enrolled 2 female and 20 male patients in this study. The evaluative tools included tinnitus frequency- and loudness-matching, tinnitus questionnaires (TQ), and the Tinnitus Handicap Inventory (THI). 〈 i 〉 Methods: 〈 /i 〉 The orthogonal projection of the auditory cortex on the scalp was focalized. A figure-eight coil was placed on the surface of the skull over the targeted region with the intensity setting at 80% of the resting motor threshold. We delivered 900 pulses of theta-burst rTMS daily for 10 business days. 〈 i 〉 Main Outcome Measures: 〈 /i 〉 Nine of twelve patients (75%) in the active-stimulation group reported tinnitus suppression following treatment with rTMS. The treatment led to reductions of 8.58 and 8.33 in the mean TQ global and THI scores, respectively. Tinnitus loudness also decreased significantly after delivering rTMS. 〈 i 〉 Results: 〈 /i 〉 Descriptive analysis of the TQs revealed that patients experienced significant improvements in emotional distress levels and somatic symptoms. 〈 i 〉 Conclusions: 〈 /i 〉 Our preliminary results demonstrate that theta-burst rTMS treatments offer a method of modulating tinnitus. Patients could benefit from emotional improvements, even more than auditory perceptive relief. Further studies are needed to establish a standard protocol and to clarify nervous propagation along the auditory and psychological projection following treatment with rTMS.
    Type of Medium: Online Resource
    ISSN: 1420-3030 , 1421-9700
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2012
    detail.hit.zdb_id: 1481979-X
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  • 2
    Online Resource
    Online Resource
    Elsevier BV ; 2021
    In:  Journal of Voice Vol. 35, No. 2 ( 2021-03), p. 300-306
    In: Journal of Voice, Elsevier BV, Vol. 35, No. 2 ( 2021-03), p. 300-306
    Type of Medium: Online Resource
    ISSN: 0892-1997
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 2111437-7
    SSG: 7,11
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  • 3
    Online Resource
    Online Resource
    Acoustical Society of America (ASA) ; 2015
    In:  Journal of the Acoustical Society of America Vol. 137, No. 4_Supplement ( 2015-04-01), p. 2226-2226
    In: Journal of the Acoustical Society of America, Acoustical Society of America (ASA), Vol. 137, No. 4_Supplement ( 2015-04-01), p. 2226-2226
    Abstract: Objective: Previous research has shown the usefulness of utilizing auditory chimeras (i.e., interchanging the envelope and fine structure of two different sounds) in assessing a listener’s perception of the envelope and fine structure for an acoustic stimulus. However, research comparing and contrasting behavioral and electrophysiological responses to this stimulus type is scarce. Design: Two sets of chimeric stimuli were constructed by interchanging the envelopes and fine-structures of the rising /yi2/ and falling /yi4/ Mandarin pitch contours that were filtered through 1, 2, 4, 8, 16, 32, and 64 frequency banks. Behavioral pitch-perception tasks (through a single-interval, two-alternative, forced-choice paradigm) and electrophysiological responses (through the frequency-following response to voice pitch using validated scalp-recorded potential methods) were obtained from two groups of participants (native speakers of a tonal or nontonal language). Study Sample: Thirteen American and 13 Chinese adults were recruited. Results: A two-way analysis of variance showed significance (p & lt;0.05) within and across the filter bank and language background factors for the behavioral measurements to the lexical-tone chimeras, while the frequency-following response demonstrated a significance across filter banks, but not for language background. Conclusions: Frequency-following responses to voice pitch provide supplementary information on how chimeric stimuli are processed at the brainstem level.
    Type of Medium: Online Resource
    ISSN: 0001-4966 , 1520-8524
    RVK:
    Language: English
    Publisher: Acoustical Society of America (ASA)
    Publication Date: 2015
    detail.hit.zdb_id: 1461063-2
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