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  • 1
    Online Resource
    Online Resource
    Cambridge University Press (CUP) ; 2022
    In:  Journal of Child Language Vol. 49, No. 3 ( 2022-05), p. 486-502
    In: Journal of Child Language, Cambridge University Press (CUP), Vol. 49, No. 3 ( 2022-05), p. 486-502
    Abstract: This article presents data on lexical development of 881 Israeli Hebrew-speaking monolingual toddlers ages 1;0 to 2;0. A Web-based version of the Hebrew MacArthur-Bates Communicative Development Inventories (H-MB-CDI) was used for data collection. Growth curves for expressive vocabulary, receptive vocabulary, actions and gestures were characterized. Developmental trajectories of toddlers with various demographic characteristics, such as education, income, religiosity level, birth order of the child, and child-care arrangements were compared. Results show that the lexical growth curves for Hebrew are comparable to those reported for other languages. Sex, birth order, and child-care arrangements were found to influence the size of lexicons. It is recommended that the trajectories presented here be used as norms for lexical growth among typical Hebrew-speaking toddlers in the second year of life.
    Type of Medium: Online Resource
    ISSN: 0305-0009 , 1469-7602
    RVK:
    RVK:
    Language: English
    Publisher: Cambridge University Press (CUP)
    Publication Date: 2022
    detail.hit.zdb_id: 1466489-6
    SSG: 5,2
    SSG: 7,11
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  • 2
    In: Science, American Association for the Advancement of Science (AAAS), Vol. 353, No. 6301 ( 2016-08-19)
    Abstract: Microglia, the resident myeloid cells of the central nervous system, play important roles in life-long brain maintenance and in pathology. Despite their importance, their regulatory dynamics during brain development have not been fully elucidated. Using genome-wide chromatin and expression profiling coupled with single-cell transcriptomic analysis throughout development, we found that microglia undergo three temporal stages of development in synchrony with the brain—early, pre-, and adult microglia—which are under distinct regulatory circuits. Knockout of the gene encoding the adult microglia transcription factor MAFB and environmental perturbations, such as those affecting the microbiome or prenatal immune activation, led to disruption of developmental genes and immune response pathways. Together, our work identifies a stepwise microglia developmental program integrating immune response pathways that may be associated with several neurodevelopmental disorders.
    Type of Medium: Online Resource
    ISSN: 0036-8075 , 1095-9203
    RVK:
    RVK:
    Language: English
    Publisher: American Association for the Advancement of Science (AAAS)
    Publication Date: 2016
    detail.hit.zdb_id: 128410-1
    detail.hit.zdb_id: 2066996-3
    detail.hit.zdb_id: 2060783-0
    SSG: 11
    Location Call Number Limitation Availability
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  First Language Vol. 41, No. 6 ( 2021-12), p. 779-793
    In: First Language, SAGE Publications, Vol. 41, No. 6 ( 2021-12), p. 779-793
    Abstract: During the second year of life, children acquire words and expand their receptive and expressive vocabularies at a rapid pace. At this age, toddlers’ phonological abilities are also developing rapidly. The current study investigated the effect of phonological complexity of words on the order in which they are acquired, receptively and expressively. Data were collected from Hebrew-speaking parents of 881 typically developing toddlers: 417 girls and 464 boys, aged 1;0 to 2;0 years old. Parents reported on their child’s receptive and expressive vocabularies by completing a computerized version of the Hebrew adaptation of the MacArthur-Bates Communicative Development Inventories. Phonological complexity scores of the target words were calculated using the Phonological Mean Length of Utterances measure. The proportion of children who were reported to understand and produce each word at each age was calculated. Results showed that phonological complexity affected the acquisition of word comprehension and word production. Words that are less phonologically complex were acquired earlier, representing a process of subconscious selection of words that are easier to produce.
    Type of Medium: Online Resource
    ISSN: 0142-7237 , 1740-2344
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2124155-7
    SSG: 7,11
    Location Call Number Limitation Availability
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