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  • 1
    Online Resource
    Online Resource
    Epigenetic Manipulation Induces the Production of Coumarin‐Type Secondary Metabolite from Arthrobotrys foliicola
    Wiley ; 2019
    In:  Israel Journal of Chemistry Vol. 59, No. 5 ( 2019-05), p. 432-438
    Details
    In: Israel Journal of Chemistry, Wiley, Vol. 59, No. 5 ( 2019-05), p. 432-438
    Abstract: Pursuing epigenetic manipulation approach in fungi led to the isolation of an unusual coumarin metabolite from fungi. An addition of the histone deacetylase inhibitor, suberohydroxamic acid (SBHA), to the culture medium of Arthrobotrys foliicola induced production of the coumarin‐type secondary metabolite represented by a single intensive peak in the HPLC profile of the ethyl acetate extract. The compound which was identified as 4‐ethyl‐7‐hydroxy‐8‐methyl‐2 H ‐chromen‐2‐one ( 1 ) was isolated from nature for the first time. Moreover, the investigation on the remaining part of the HPLC profile led to the separation of 6‐ethyl‐2,4‐dihydroxy‐3‐methylbenzaldehyde ( 2 ) and ten 2,5‐diketopiperazine compounds ( 3 – 12 ). The structures of isolates were deduced by their mass and NMR spectroscopic data. The coumarin‐type secondary metabolite ( 1 ) with peculiar smell induced by epigenetic stimulation is found for the first time in the Arthrobotrys species and the family Orbiliaceae. We evaluated 1 for the cytotoxic, anti‐inflammatory, anti‐allergic and nematocidal activities, however, it was found inactive.
    Type of Medium: Online Resource
    ISSN: 0021-2148 , 1869-5868
    URL: Issue
    URL: Article
    DOI: 10.1002/ijch.v59.5
    DOI: 10.1002/ijch.201800162
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2066481-3
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  • 2
    Online Resource
    Online Resource
    Hydroperoxyditerpenoids from Octocorals
    Wiley ; 2019
    In:  Israel Journal of Chemistry Vol. 59, No. 5 ( 2019-05), p. 403-413
    Details
    In: Israel Journal of Chemistry, Wiley, Vol. 59, No. 5 ( 2019-05), p. 403-413
    Abstract: The structures, names, bioactivities, and references of 75 marine diterpenoids from octocorals possessing a hydroperoxy group, including 46 cembranes, 8 eunicellins, 5 briaranes, 5 dolabellanes, 4 germacranes, 3 xenicins, 2 caryophyllanes, 1 decalin, and 1 pseudopterosin, are summarized in this review article. All the hydroperoxyditerpenoids mentioned in this review were isolated from octocorals from Alcyonacea (Briareum excavatum, Briareum polyanthes, Briareum violaceum, Briareum sp., Cespitularia sp., Cladiella tuberculosa, Cladiella sp., Clavularia inflata, Klyxum simplex, Lemnalia sp., Lobophytum crassum, Lobophytum sp., Nephthea pacifica, Sarcophyton cherbonnieri, Sarcophyton crassocaule, Sarcophyton glaucum, Sarcophyton mililatensis, Sarcophyton trocheliophorum, Sarcophyton sp., Sinularia arborea, Sinularia erecta, Sinilaria flexibilis, Sinularia gibberosa, Sinularia manaarensis, Xenia umbellata) and Gorgonacea (Astrogorgia sp., Eunicea calyculata, Eunicea pinta, Eunicea succinea, Eunicea sp., Pseudopterogorgia sp.). Among these isolates, 41 compounds exhibited potential biomedical activities, including cytotoxicity, antimalarial activity, anti‐inflammatory activity, and antibacterial activity.
    Type of Medium: Online Resource
    ISSN: 0021-2148 , 1869-5868
    URL: Issue
    URL: Article
    DOI: 10.1002/ijch.v59.5
    DOI: 10.1002/ijch.201900011
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2066481-3
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  • 3
    Online Resource
    Online Resource
    Effects of guar gum supplementation in high-fat diets on fish growth, gut histology, intestinal oxidative stress, inflammation, and apoptosis in juvenile largemouth bass ( Micropterus salmoides )
    SAABRON PRESS ; 2023
    In:  Israeli Journal of Aquaculture - Bamidgeh Vol. 75 ( 2023-6-14)
    Details
    In: Israeli Journal of Aquaculture - Bamidgeh, SAABRON PRESS, Vol. 75 ( 2023-6-14)
    Abstract: The present study aimed to investigate the influence of guar gum supplementation in high-fat diets on the growth performance and intestinal oxidative stress, inflammation, and apoptosis of juvenile largemouth bass. Five isonitrogenous diets were prepared: a control diet (10% crude lipid, C), a high-fat diet (17% crude lipid, HF), and three high-fat diets supplemented with 0.3% guar gum (GG0.3), 1% guar gum (GG1), and 3% guar gum (GG3). Largemouth bass (3.1±0.2 g) were randomly assigned to fifteen tanks (30 fish/tank) and fed for 8 weeks. The results demonstrated that GG0.3 significantly increased specific growth rate (SGR) and increased feed conversion ratio (FCR) compared to HF (P 〈 0.05). For histology, high-fat diets containing guar gum significantly increased intestinal villus length, villus width, and perimeter ratio, compared with HF (P 〈 0.05). Compared with Control, HF significantly decreased reduced glutathione (GSH) contents and increased malondialdehyde (MDA) contents in the intestine (P 〈 0.05). Additionally, HF significantly increased the expression of interleukin 1β (IL-1β), tumor necrosis factor α (TNF-α), and cysteine-aspartic proteases 9 (Caspase 9) in the intestine (P 〈 0.05). Compared to HF, GG0.3 significantly decreased MDA contents, increased GSH contents, and downregulated the expression of IL-1β, TNF-α, and Caspase 3 than diet HF in the intestine (P 〈 0.05). These results suggest that guar gum can alleviate the adverse effects of high-fat diets on growth and gut health in fish.
    Type of Medium: Online Resource
    ISSN: 0792-156X , 0792-156X
    URL: Article
    DOI: 10.46989/001c.77976
    Language: English
    Publisher: SAABRON PRESS
    Publication Date: 2023
    detail.hit.zdb_id: 291787-7
    detail.hit.zdb_id: 2542938-3
    SSG: 21,3
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  • 4
    Online Resource
    Online Resource
    Effect of Marine Red Yeast Rhodosporidium paludigenum on Antioxidant-Related Gene Expression in Litopenaeus vannamei
    SAABRON PRESS ; 2013
    In:  Israeli Journal of Aquaculture - Bamidgeh Vol. 65 ( 2013-1-1)
    Details
    In: Israeli Journal of Aquaculture - Bamidgeh, SAABRON PRESS, Vol. 65 ( 2013-1-1)
    Abstract: The effects of orally-administered dry and live marine red yeast Rhodosporidium paludigenum on antioxidant-related gene expression in the hepatopancreas and hemocytes of Litopenaeus vannamei were investigated by RT-PCR. In the hepatopancreas of L. vannamei fed dry yeast, manganese superoxidate dismutase (SODMn) and catalase (CAT) were enhanced while glutathione peroxidase (GPx) and ferritin remained at the same levels as in the control group. In the hepatopancreas of L. vannamei fed live yeast, SODMn and ferritin were higher than in the control. In hemocytes of L. vannamei fed dry yeast, SODMn was lower, ferritin was similar, and CAT and GPx fluctuated, in comparison to the control. In hemocytes of L. vannamei fed live yeast, SODMn was lower, ferritin was higher, and CAT and GPx tended to be lower than in the control group. Results suggest that consumption of the marine red yeast, R. paludigenum, can stimulate antioxidant gene expression in the hepatopancreas of shrimp.
    Type of Medium: Online Resource
    ISSN: 0792-156X , 0792-156X
    URL: Article
    DOI: 10.46989/001c.20665
    Language: English
    Publisher: SAABRON PRESS
    Publication Date: 2013
    detail.hit.zdb_id: 291787-7
    detail.hit.zdb_id: 2542938-3
    SSG: 21,3
    Location Call Number Limitation Availability
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    Online Resource
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