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  • Biodiversity Research  (388)
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  • 1
    Online Resource
    Online Resource
    Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways
    Springer Science and Business Media LLC ; 2012
    In:  Molecular Biology Reports Vol. 39, No. 4 ( 2012-4), p. 3549-3556
    Details
    In: Molecular Biology Reports, Springer Science and Business Media LLC, Vol. 39, No. 4 ( 2012-4), p. 3549-3556
    Type of Medium: Online Resource
    ISSN: 0301-4851 , 1573-4978
    URL: Article
    DOI: 10.1007/s11033-011-1128-0
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2012
    detail.hit.zdb_id: 1478217-0
    SSG: 12
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  • 2
    Online Resource
    Online Resource
    Protective effect of the glucagon-like peptide-1 analogue liraglutide on carbon tetrachloride-induced acute liver injury in mice
    Elsevier BV ; 2019
    In:  Biochemical and Biophysical Research Communications Vol. 514, No. 2 ( 2019-06), p. 386-392
    Details
    In: Biochemical and Biophysical Research Communications, Elsevier BV, Vol. 514, No. 2 ( 2019-06), p. 386-392
    Type of Medium: Online Resource
    ISSN: 0006-291X
    URL: Article
    DOI: 10.1016/j.bbrc.2019.04.160
    RVK:
    WA 15000
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
    detail.hit.zdb_id: 1461396-7
    SSG: 12
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  • 3
    Online Resource
    Online Resource
    Isolation, Diversity, and Antimicrobial Activity of Rare Actinobacteria from Medicinal Plants of Tropical Rain Forests in Xishuangbanna, China
    American Society for Microbiology ; 2009
    In:  Applied and Environmental Microbiology Vol. 75, No. 19 ( 2009-10), p. 6176-6186
    Details
    In: Applied and Environmental Microbiology, American Society for Microbiology, Vol. 75, No. 19 ( 2009-10), p. 6176-6186
    Abstract: Endophytic actinobacteria are relatively unexplored as potential sources of novel species and novel natural products for medical and commercial exploitation. Xishuangbanna is recognized throughout the world for its diverse flora, especially the rain forest plants, many of which have indigenous pharmaceutical histories. However, little is known about the endophytic actinobacteria of this tropical area. In this work, we studied the diversity of actinobacteria isolated from medicinal plants collected from tropical rain forests in Xishuangbanna. By the use of different selective isolation media and methods, a total of 2,174 actinobacteria were isolated. Forty-six isolates were selected on the basis of their morphologies on different media and were further characterized by 16S rRNA gene sequencing. The results showed an unexpected level of diversity, with 32 different genera. To our knowledge, this is the first report describing the isolation of Saccharopolyspora , Dietzia , Blastococcus , Dactylosporangium , Promicromonospora , Oerskovia , Actinocorallia , and Jiangella species from endophytic environments. At least 19 isolates are considered novel taxa by our current research. In addition, all 46 isolates were tested for antimicrobial activity and were screened for the presence of genes encoding polyketide synthetases and nonribosomal peptide synthetases. The results confirm that the medicinal plants of Xishuangbanna represent an extremely rich reservoir for the isolation of a significant diversity of actinobacteria, including novel species, that are potential sources for the discovery of biologically active compounds.
    Type of Medium: Online Resource
    ISSN: 0099-2240 , 1098-5336
    URL: Article
    DOI: 10.1128/AEM.01034-09
    RVK:
    WA 15000
    Language: English
    Publisher: American Society for Microbiology
    Publication Date: 2009
    detail.hit.zdb_id: 223011-2
    detail.hit.zdb_id: 1478346-0
    SSG: 12
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  • 4
    Online Resource
    Online Resource
    Streptomyces artemisiae sp. nov., isolated from surface-sterilized tissue of Artemisia annua L.
    Microbiology Society ; 2010
    In:  International Journal of Systematic and Evolutionary Microbiology Vol. 60, No. 1 ( 2010-01-01), p. 27-32
    Details
    In: International Journal of Systematic and Evolutionary Microbiology, Microbiology Society, Vol. 60, No. 1 ( 2010-01-01), p. 27-32
    Abstract: The taxonomic position of an actinomycete strain YIM 63135 T , which was isolated from the surface-sterilized tissue of Artemisia annua L. collected from Yunnan province, south-west China, was determined by using a polyphasic approach. Morphological and chemical characteristics of the novel strain were consistent with those of the genus Streptomyces . It developed a pinkish aerial mycelium and pinkish-brown substrate mycelium on oatmeal agar. The cell wall of the strain contained ll -diaminopimelic acid. The menaquinones comprised MK-9(H 6 ) (62.8 %), MK-9(H 8 ) (31.4 %) and MK-9(H 4 ) (5.9 %). The phospholipids were diphosphatidylglycerol, phosphatidylglycerol, phosphatidylinositol, phosphatidylethanolamine, an unknown glucosamine-containing phospholipid (GluNu), phosphatidylinositol mannosides and four unknown ninhydrin-negative phospholipids. The major fatty acids were iso-C 16 : 0 (30.0 %), anteiso-C 17 : 0 (27.3 %) and anteiso-C 15 : 0 (17.0 %). The DNA G + C content of strain YIM 63135 T was 72.6 mol%. Phylogenetic analysis of 16S rRNA gene sequences revealed that strain YIM 63135 T is a member of the genus Streptomyces and exhibited 99.9 % gene sequence similarity to Streptomyces armeniacus NBRC 12555 T , while low sequence similarity values ( 〈 97.0 %) distinguished strain YIM 63135 T from all other Streptomyces species. DNA–DNA hybridization studies suggested that strain YIM 63135 T represents a different genomic species. On the basis of phenotypic and phylogenetic characteristics, strain YIM 63135 T was considered to represent a novel species of the genus Streptomyces , for which the name Streptomyces artemisiae sp. nov. is proposed, with YIM 63135 T (=CCTCC AA 208059 T =DSM 41953 T ) as the type strain.
    Type of Medium: Online Resource
    ISSN: 1466-5026 , 1466-5034
    URL: Article
    DOI: 10.1099/ijs.0.011965-0
    Language: English
    Publisher: Microbiology Society
    Publication Date: 2010
    detail.hit.zdb_id: 215062-1
    detail.hit.zdb_id: 2056611-6
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  • 5
    Online Resource
    Online Resource
    Nonomuraea rhizophila sp. nov., an actinomycete isolated from rhizosphere soil
    Microbiology Society ; 2011
    In:  International Journal of Systematic and Evolutionary Microbiology Vol. 61, No. 9 ( 2011-09-01), p. 2141-2145
    Details
    In: International Journal of Systematic and Evolutionary Microbiology, Microbiology Society, Vol. 61, No. 9 ( 2011-09-01), p. 2141-2145
    Abstract: A novel actinomycete, designated strain YIM 67092 T , was isolated from rhizosphere soil of the perennial vine Tripterygium wilfordii Hook. f. collected from Yunnan province, South-west China. The strain formed well differentiated aerial and substrate mycelia and grew in the presence of up to 7 % (w/v) NaCl. Phylogenetic analysis based on the 16S rRNA gene showed that strain YIM 67092 T belonged to the genus Nonomuraea , with highest sequence similarity to Nonomuraea rosea GW 12687 T (99.0 %). Sequence similarities between strain YIM 67092 T and other species of the genus Nonomuraea ranged from 97.8 % ( Nonomuraea dietziae DSM 44320 T ) to 93.8 % ( Nonomuraea kuesteri GW 14-1925 T ). Key morphological, physiological and chemotaxonomic characteristics of strain YIM 67092 T were congruent with the description of the genus Nonomuraea . The G+C content of the genomic DNA was 69.3 mol%. Based on comparative analysis of physiological, biochemical and chemotaxonomic data, including low DNA–DNA hybridization results, strain YIM 67092 T represents a novel species of the genus Nonomuraea , for which the name Nonomuraea rhizophila sp. nov. is proposed. The type strain is YIM 67092 T ( = CCTCC AA 209044 T  = DSM 45382 T ).
    Type of Medium: Online Resource
    ISSN: 1466-5026 , 1466-5034
    URL: Article
    DOI: 10.1099/ijs.0.028050-0
    Language: English
    Publisher: Microbiology Society
    Publication Date: 2011
    detail.hit.zdb_id: 215062-1
    detail.hit.zdb_id: 2056611-6
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  • 6
    Online Resource
    Online Resource
    Promicromonospora xylanilytica sp. nov., an endophytic actinomycete isolated from surface-sterilized leaves of the medicinal plant Maytenus austroyunnanensis
    Microbiology Society ; 2012
    In:  International Journal of Systematic and Evolutionary Microbiology Vol. 62, No. 1 ( 2012-01-01), p. 84-89
    Details
    In: International Journal of Systematic and Evolutionary Microbiology, Microbiology Society, Vol. 62, No. 1 ( 2012-01-01), p. 84-89
    Abstract: A novel xylan-degrading actinomycete, strain YIM 61515 T , was isolated from surface-sterilized leaves of the medicinal plant Maytenus austroyunnanensis . Cells were Gram-positive and non-spore-forming, produced primary branches and formed white to yellowish white colonies on the media tested. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain YIM 61515 T was most similar to Promicromonospora aerolata V54A T and Promicromonospora vindobonensis V45 T (99.4 and 99.1 % sequence similarity, respectively). The isolate formed a separate lineage in a cluster containing P. aerolata V54A T . 16S rRNA gene sequence similarity between the isolate and other members of the genus Promicromonospora ranged from 96.3 to 98.4 %. Chemotaxonomic data, including major menaquinones, fatty acid compositions and polar lipid profiles, supported the placement of strain YIM 61515 T in the genus Promicromonospora . DNA–DNA relatedness, physiological and biochemical data showed that strain YIM 61515 T could be distinguished from members of all known species of the genus Promicromonospora and therefore represented a novel species. The name Promicromonospora xylanilytica sp. nov. is proposed, with YIM 61515 T ( = DSM 21603 T  = CCTCC AA 208046 T ) as type strain.
    Type of Medium: Online Resource
    ISSN: 1466-5026 , 1466-5034
    URL: Article
    DOI: 10.1099/ijs.0.032185-0
    Language: English
    Publisher: Microbiology Society
    Publication Date: 2012
    detail.hit.zdb_id: 215062-1
    detail.hit.zdb_id: 2056611-6
    SSG: 12
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  • 7
    Online Resource
    Online Resource
    Sphingomonas endophytica sp. nov., isolated from Artemisia annua L.
    Microbiology Society ; 2012
    In:  International Journal of Systematic and Evolutionary Microbiology Vol. 62, No. Pt_7 ( 2012-07-01), p. 1576-1580
    Details
    In: International Journal of Systematic and Evolutionary Microbiology, Microbiology Society, Vol. 62, No. Pt_7 ( 2012-07-01), p. 1576-1580
    Abstract: A novel bacterium (strain YIM 65583 T ) belonging to the genus Sphingomonas was isolated from surface-sterilized tissue of Artemisia annua L., which was collected from Yunnan province, south-west China. Its morphology, physiology and biochemical features were consistent with those of members of the genus Sphingomonas . Analysis of the 16S rRNA gene sequence of strain YIM 65583 T further confirmed that it should be classified as a member of the genus Sphingomonas and was most closely related to Sphingomonas phyllosphaerae FA2 T (99.7 %) and Sphingomonas yunnanensis YIM 003 T (98.3 %). The isolate was Gram-negative and formed yellow-pigmented colonies on ISP 2 medium. It grew optimally at pH 6.0–8.0, at 20–37 °C and in the presence of 0–1 % (w/v) NaCl. The major respiratory lipoquinone was ubiquinone-10; C 18 : 1 ω7 c , anteiso-C 16 : 1 , C 14 : 0 -2OH, C 17 : 1 ω6 c , C 16 : 0 and C 15 : 0 were the major fatty acids. Major polar lipids were diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, phosphatidylcholine and sphingoglycolipid. The G+C content of the genomic DNA was 63.3 mol%. The DNA–DNA relatedness values of the isolate YIM 65583 T with S. phyllosphaerae FA2 T and S. yunnanensis YIM 003 T were 43.1 % and 37.9 %, respectively. Based on these features, it is concluded that the strain represents a novel species of the genus Sphingomona s, for which the name Sphingomonas endophytica sp. nov. is proposed, with YIM 65583 T ( = CCTCC AA 209035 T  = JCM 17394 T ) as the type strain.
    Type of Medium: Online Resource
    ISSN: 1466-5026 , 1466-5034
    URL: Article
    DOI: 10.1099/ijs.0.031484-0
    Language: English
    Publisher: Microbiology Society
    Publication Date: 2012
    detail.hit.zdb_id: 215062-1
    detail.hit.zdb_id: 2056611-6
    SSG: 12
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  • 8
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    Online Resource
    Rothia endophytica sp. nov., an actinobacterium isolated from Dysophylla stellata (Lour.) Benth
    Microbiology Society ; 2013
    In:  International Journal of Systematic and Evolutionary Microbiology Vol. 63, No. Pt_11 ( 2013-11-01), p. 3964-3969
    Details
    In: International Journal of Systematic and Evolutionary Microbiology, Microbiology Society, Vol. 63, No. Pt_11 ( 2013-11-01), p. 3964-3969
    Abstract: A novel endophytic actinobacterium, designated strain YIM 67072 T , was isolated from healthy roots of Dysophylla stellata (Lour.) Benth. Cells of this aerobic, cream–yellow-coloured strain occurred singly, in pairs or in tetrads, were Gram-stain-positive and ovoid- to spherical-shaped. Strain YIM 67072 T grew at 4–45 °C, pH 5.0–10.0 and in the presence of 0–7 % (w/v) NaCl. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain YIM 67072 T belonged to the genus Rothia . The isolate contained MK-7 as the major component of the quinone system. The peptidoglycan type was A3α. The polar lipid profile consisted predominantly of diphosphatidylglycerol and glycolipids. The major fatty acids were anteiso-C 15 : 0 , iso-C 15 : 0 , anteiso-C 17 : 0 and iso-C 16 : 0 . The DNA G+C content was 53.2 mol%. However, strain YIM 67072 T differed from its closest relatives Rothia nasimurium CCUG 35957 T (98.5 % 16S rRNA gene sequence similarity), Rothia amarae JCM 11375 T (97.6 %) and Rothia terrae L-143 T (97.3 %) in many phenotypic characteristics. Moreover, the levels of DNA–DNA relatedness between the novel isolate and the three above-mentioned type strains were 28.7±1.3 %, 36.5±1.2 %, 46.8±1.5 %, respectively. Based on comparative analysis of physiological and chemotaxonomic data, strain YIM 67072 T represents a novel species of the genus Rothia , for which the name Rothia endophytica sp. nov. is proposed. The type strain is YIM 67072 T ( = DSM 26247 T  = JCM 18541 T ).
    Type of Medium: Online Resource
    ISSN: 1466-5026 , 1466-5034
    URL: Article
    DOI: 10.1099/ijs.0.052522-0
    Language: English
    Publisher: Microbiology Society
    Publication Date: 2013
    detail.hit.zdb_id: 215062-1
    detail.hit.zdb_id: 2056611-6
    SSG: 12
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  • 9
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    Actinorugispora endophytica gen. nov., sp. nov., an actinomycete isolated from Daucus carota
    Microbiology Society ; 2015
    In:  International Journal of Systematic and Evolutionary Microbiology Vol. 65, No. Pt_8 ( 2015-08-01), p. 2562-2568
    Details
    In: International Journal of Systematic and Evolutionary Microbiology, Microbiology Society, Vol. 65, No. Pt_8 ( 2015-08-01), p. 2562-2568
    Abstract: An actinomycete strain, designated YIM 690008 T , was isolated from Daucus carota collected from South Korea and its taxonomic position was investigated by using a polyphasic approach. The strain grew well on most media tested and no diffusible pigment was produced. The aerial mycelium formed wrinkled single spores and short spore chains, some of which were branched. The whole-cell hydrolysates contained meso -diaminopimelic acid, glucose, mannose, ribose, galactose and rhamnose. The predominant menaquinones were MK-10(H 4 ), MK-10(H 6 ), MK-10(H 8 ) and MK-10(H 2 ). The polar lipids were diphosphatidylglycerol, phosphatidylcholine, phosphatidylinositol, phosphatidylinositol mannosides, some unknown phospholipids, glycolipids and polar lipids. The major fatty acids were i-C 16 : 0 , ai-C 17 : 0 and C 18 : 1 ω9 c . The DNA G+C content of the genomic DNA was 63.1 mol%. Phylogenetic analysis indicated that the isolate belongs to the family Nocardiopsaceae . However, based on phenotypic, chemotaxonomic and genotypic data, it was concluded that strain YIM 690008 T represents a novel genus and novel species of the family Nocardiopsaceae , for which the name Actinorugispora endophytica gen. nov., sp. nov. (type strain YIM 690008 T  = DSM 46770 T  = JCM 30099 T  = KCTC 29480 T ) is proposed.
    Type of Medium: Online Resource
    ISSN: 1466-5026 , 1466-5034
    URL: Article
    DOI: 10.1099/ijs.0.000304
    Language: English
    Publisher: Microbiology Society
    Publication Date: 2015
    detail.hit.zdb_id: 215062-1
    detail.hit.zdb_id: 2056611-6
    SSG: 12
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  • 10
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    Rhodococcus artemisiae sp. nov., an endophytic actinobacterium isolated from the pharmaceutical plant Artemisia annua L.
    Microbiology Society ; 2012
    In:  International Journal of Systematic and Evolutionary Microbiology Vol. 62, No. Pt_4 ( 2012-04-01), p. 900-905
    Details
    In: International Journal of Systematic and Evolutionary Microbiology, Microbiology Society, Vol. 62, No. Pt_4 ( 2012-04-01), p. 900-905
    Abstract: A Gram-positive, non-motile actinobacterium, designated YIM 65754 T , was isolated from the stem of Artemisia annua L., collected from Yunnan province, south-west China. Phylogenetic analysis based on 16S rRNA gene sequences revealed that strain YIM 65754 T comprised an evolutionary lineage within the genus Rhodococcus . The isolate clustered with Rhodococcus pyridinivorans PDB9 T , Rhodococcus gordoniae W 4937 T and Rhodococcus rhodochrous DSM 43241 T , with which it shared 98.4, 97.9 and 97.8 % 16S rRNA gene sequence similarities, respectively. However, DNA–DNA relatedness demonstrated that strain YIM 65754 T was distinct from its closest phylogenetic neighbours. The cell-wall peptidoglycan contained meso -diaminopimelic acid, arabinose, galactose, mannose and glucose (cell-wall chemotype IV). The major menaquinone was MK-8(H 2 ) and the predominant fatty acids were C 16 : 0 (27.83 %), iso-C 15 : 0 2-OH and/or C 16 : 1 ω7 c (20.21 %) and 10-methyl C 18 : 0 (17.50 %). The DNA G+C content was 66.2 mol%. On the basis of phenotypic, chemotaxonomic and phylogenetic evidence, the isolate represents a novel species of the genus Rhodococcus , for which the name Rhodococcus artemisiae sp. nov. is proposed; the type strain is YIM 65754 T ( = CCTCC AA 209042 T  = DSM 45380 T ).
    Type of Medium: Online Resource
    ISSN: 1466-5026 , 1466-5034
    URL: Article
    DOI: 10.1099/ijs.0.031930-0
    Language: English
    Publisher: Microbiology Society
    Publication Date: 2012
    detail.hit.zdb_id: 215062-1
    detail.hit.zdb_id: 2056611-6
    SSG: 12
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