In:
Arhiv za bioloske nauke, National Library of Serbia, Vol. 66, No. 2 ( 2014), p. 729-734
Abstract:
The effect of 5,10-methylenetetrahydrofolate reductase (MTHFR) gene C677T
polymorphism on serum lipid profiles is controversial. We randomly selected
530 healthy schoolchildren that were included in the Yugoslav Study of the
Precursors of Atherosclerosis in School Children (YUSAD). The detected
frequencies of MTHFR 677TT genotypes and MTHFR 677T allele were 13.4% and
35.5%, respectively. The mean levels of total cholesterol, low-density
lipoprotein cholesterol and triglycerides were higher and high-density
lipoprotein cholesterol was lower in the group of children with TT genotype
compared with remaining genotypes. All differences were without statistical
significance. Our findings suggest that there is no influence of MTHFR C677T
gene variants on the lipid parameters in the population of Serbian children.
Type of Medium:
Online Resource
ISSN:
0354-4664
,
1821-4339
Language:
English
Publisher:
National Library of Serbia
Publication Date:
2014
detail.hit.zdb_id:
2380842-1
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