In:
Zeitschrift für Naturforschung C, Walter de Gruyter GmbH, Vol. 64, No. 3-4 ( 2009-4-1), p. 307-310
Abstract:
7-Ketocholesterol (7-Kchol, oxidized cholesterol) is an important mediator of cell death in atherosclerosis mediated by up-regulated Nox 4 gene expression. In the current study using the human colon cancer HT-29 cell line, we have demonstrated that 7-Kchol promotes endoplasmic reticulum (ER) stress via gene up-regulation of ER chaperone and membrane kinases.
Type of Medium:
Online Resource
ISSN:
1865-7125
,
0939-5075
DOI:
10.1515/znc-2009-3-425
Language:
English
Publisher:
Walter de Gruyter GmbH
Publication Date:
2009
detail.hit.zdb_id:
2078107-6
SSG:
12
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