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  • 1
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 1979
    In:  Biotechnology Letters Vol. 1, No. 9 ( 1979-9), p. 371-376
    In: Biotechnology Letters, Springer Science and Business Media LLC, Vol. 1, No. 9 ( 1979-9), p. 371-376
    Type of Medium: Online Resource
    ISSN: 0141-5492 , 1573-6776
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 1979
    detail.hit.zdb_id: 2012203-2
    SSG: 12
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  • 2
    In: Biogeosciences, Copernicus GmbH, Vol. 16, No. 1 ( 2019-01-08), p. 17-32
    Abstract: Abstract. Tropical peat-draining rivers are known as potentially large sources of carbon dioxide (CO2) to the atmosphere due to the high loads of carbon they receive from surrounding soils. However, not many seasonally resolved data are available, limiting our understanding of these systems. We report the first measurements of carbon dioxide partial pressure (pCO2) in the Rajang River and Estuary, the longest river in Malaysia. The Rajang River catchment is characterized by extensive peat deposits found in the delta region, and by human impact such as logging, land use and river damming. pCO2 averaged 2540±189 µatm during the wet season and 2350±301 µatm during the dry season. Using three different parameterizations for the gas transfer velocity, calculated CO2 fluxes to the atmosphere were 1.5 (0.5–2.0) g C m−2 d−1 (mean, minimum – maximum) during the wet season and 1.7 (0.6–2.6) g C m−2 d−1 during the dry season. This is at the low end of reported values for Southeast Asian peat-draining rivers, but similar to values reported for Southeast Asian rivers that do not flow through peat deposits. In the Rajang River, peatlands probably do not contribute much to the CO2 flux due to the proximity of the peatlands to the coast, which limits the opportunity for degradation of organic C during transport. Thus, we suggest that peat coverage is, by itself, insufficient as the sole predictor of CO2 emissions from peat-draining rivers, and that other factors, like the spatial distribution of peat in the catchment and pH, also need to be considered.
    Type of Medium: Online Resource
    ISSN: 1726-4189
    Language: English
    Publisher: Copernicus GmbH
    Publication Date: 2019
    detail.hit.zdb_id: 2158181-2
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  • 3
    In: Parasites & Vectors, Springer Science and Business Media LLC, Vol. 12, No. 1 ( 2019-12)
    Abstract: Onchocerciasis is a priority neglected tropical disease targeted for elimination by 2025. The standard strategy to combat onchocerciasis is annual Community-Directed Treatment with ivermectin (CDTi). Yet, high prevalence rates and transmission persist following  〉  12 rounds in South-West Cameroon. Challenges include programme coverage, adherence to, and acceptability of ivermectin in an area of Loa loa co-endemicity. Loiasis patients harbouring heavy infections are at risk of potentially fatal serious adverse events following CDTi. Alternative strategies are therefore needed to achieve onchocerciasis elimination where CDTi effectiveness is suboptimal. Methods/design We designed an implementation study to evaluate integrating World Health Organisation-endorsed alternative strategies for the elimination of onchocerciasis, namely test-and-treat with the macrofilaricide, doxycycline (TTd), and ground larviciding for suppression of blackfly vectors with the organophosphate temephos. A community-based controlled before-after intervention study will be conducted among  〉  2000 participants in 20 intervention (Meme River Basin) and 10 control (Indian River Basin) communities. The primary outcome measure is O. volvulus prevalence at follow-up 18-months post-treatment. The study involves four inter-disciplinary components: parasitology, entomology, applied social sciences and health economics. Onchocerciasis skin infection will be diagnosed by skin biopsy and Loa loa infection will be diagnosed by parasitological examination of finger-prick blood samples. A simultaneous clinical skin disease assessment will be made. Eligible skin-snip-positive individuals will be offered directly-observed treatment for 5 weeks with 100 mg/day doxycycline. Transmission assessments of onchocerciasis in the communities will be collected post-human landing catch of the local biting blackfly vector prior to ground larviciding with temephos every week (0.3 l/m 3 ) until biting rate falls below 5/person/day. Qualitative research, including in-depth interviews and focus-group discussions will be used to assess acceptability and feasibility of the implemented alternative strategies among intervention recipients and providers. Health economics will assess the cost-effectiveness of the implemented interventions. Conclusions Using a multidisciplinary approach, we aim to assess the effectiveness of TTd, alone or in combination with ground larviciding, following a single intervention round and scrutinise the acceptability and feasibility of implementing at scale in similar hotspots of onchocerciasis infection, to accelerate onchocerciasis elimination.
    Type of Medium: Online Resource
    ISSN: 1756-3305
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 2409480-8
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