In:
ChemBioChem, Wiley, Vol. 14, No. 5 ( 2013-03-18), p. 633-638
Abstract:
Novel chatechol/hydroxamate siderophores (named “fimsbactins”) were identified in Acinetobacter baumannii ATCC 17978 and Acinetobacter baylyi ADP1. The major compound, fimsbactin A, was isolated from low‐iron cultures of A. baylyi ADP1, and its chemical structure was elucidated by mass spectrometry, and detailed 1 H, 13 C and 15 N NMR spectroscopy. From inverse feeding experiments following HPLC‐MS analysis, the structures of five additional derivatives were elucidated. The gene cluster encoding the fimsbactin synthetase ( fbs ) was identified in both genomes, and mutants in fbs genes in A. baylyi were analyzed, thus allowing prediction of the fimsbactin biosynthesis pathway.
Type of Medium:
Online Resource
ISSN:
1439-4227
,
1439-7633
DOI:
10.1002/cbic.201200764
Language:
English
Publisher:
Wiley
Publication Date:
2013
detail.hit.zdb_id:
2020469-3
SSG:
12
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