In:
EMBO reports, EMBO, Vol. 24, No. 5 ( 2023-05-04)
Abstract:
image Delactylation of cyclin E2 (CCNE2) by SIRT3 suppresses hepatocellular carcinoma (HCC) development. SIRT3 is negatively correlated with lysine lactylation levels in HCC tissues. SIRT3‐mediated delactylation of CCNE2 suppresses HCC cell growth. Honokiol induces SIRT3 delactylation activity to prevent HCC growth in vivo .
Type of Medium:
Online Resource
ISSN:
1469-221X
,
1469-3178
DOI:
10.15252/embr.202256052
Language:
English
Publisher:
EMBO
Publication Date:
2023
detail.hit.zdb_id:
2025376-X
SSG:
12
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