In:
Indian Journal of Genetics and Plant Breeding (The), The Indian Society of Genetics and Plant Breeding, Vol. 79, No. 01S ( 2019-01-16)
Abstract:
Mithun (Bos frontalis) is a bovine species found in the four
North-Eastern Hilly States of India viz., Nagaland, Arunachal, Manipur and Mizoram. The 770k
BovineHDBeadChip (Illumina, CA), which is basically a highdensity SNP array was utilized for genomic characterization
of four mithun populations and to study genetic diversity present in the populations. SNP genotyping of a total 24
samples representing four mithun populations as per their geographic locations were carried out. The results indicated
that the majority of polymorphic SNPs were found to be in HWE. Observed heterozygosity ranged between 0.263±0.040
(Nagaland) to 0.299±0.044 (Arunachal). Inbreeding coefficient ranged from 0.087±0.139 for Nagaland to
0.186±0.053 for Manipur mithun. The result of the Principal Component Analysis (PCA) indicated all the mithuns were
distributed together in close proximity and no clear separation of the four populations was observed.The first
and second principal components (PC1 and PC2) explained 9.59% and 88.0% of the total variation, respectively. The
results of the STRUCTURE analysis also showed no population substructure as inferred from an increasing plot
of cross validation error, similar to PCA. In our knowledge, this is the first study on genomic characterization of any
Indian livestock species, through analysis of population structure and genetic diversity using high density SNP array.
The baseline information generated in our study will help in developing proper strategies for implementing genomic
selection and conservation of mithun.
Type of Medium:
Online Resource
ISSN:
0019-5200
,
0019-5200
DOI:
10.31742/IJGPB.79S.1.22
Language:
Unknown
Publisher:
The Indian Society of Genetics and Plant Breeding
Publication Date:
2019
SSG:
12
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