In:
Molecular Biology of the Cell, American Society for Cell Biology (ASCB), Vol. 35, No. 4 ( 2024-04-01)
Abstract:
The fine organization of the hippocampus is critical for its proper functioning. Various mechanisms such as histone modification, DNA methylation, and long noncoding RNAs are engaged in hippocampal development. However, how pyramidal neurons (PN) precisely settle and mature in the hippocampus remains largely unclear. The authors show that the histone methlytransferase SETD2 is crucial for the precise localization and maturation of PN in the hippocampal subfield CA1. This work advances current knowledge of cellular and molecular mechanisms underlying lamination process of hippocampi.
Type of Medium:
Online Resource
ISSN:
1059-1524
,
1939-4586
DOI:
10.1091/mbc.E23-12-0492
Language:
English
Publisher:
American Society for Cell Biology (ASCB)
Publication Date:
2024
detail.hit.zdb_id:
1474922-1
SSG:
12
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