In:
Chinese Journal of Chemistry, Wiley, Vol. 41, No. 16 ( 2023-08-15), p. 1921-1930
Abstract:
The radical‐mediated reductive functionalization of aryl halides has been extensively studied. However, the related radical‐mediated intermolecular reductive 1,2‐diarylation of alkenes, using aryl halides as aryl radical sources, remains unexplored. Herein, a new electrophotocatalytic intermolecular reductive 1,2‐diarylation of alkenes is reported using aryl halides and cyanoaromatics to produce polyarylated alkanes. Using synergistic cathodic reduction and visible‐light photoredox catalysis, various electron‐rich and electron‐deficient aryl halides are combined with various alkenes and cyanoaromatics to characterize the broad substrate scope, excellent functional group compatibility, and excellent selectivity of this reaction. Mechanistic investigations reveal that this reaction may proceed via a radical process initiated by the reductive generation of aryl radicals from aryl halides and terminated by radical‐radical coupling with cyanoaromatic radical anions.
Type of Medium:
Online Resource
ISSN:
1001-604X
,
1614-7065
DOI:
10.1002/cjoc.202300174
Language:
English
Publisher:
Wiley
Publication Date:
2023
detail.hit.zdb_id:
2144352-X
SSG:
6,25
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