In:
Chinese Journal of Chemistry, Wiley, Vol. 37, No. 5 ( 2019-05), p. 457-461
Abstract:
A regioselective double 1,1‐hydrosilylation of terminal aliphatic alkynes with primary silanes catalyzed by one cobalt catalyst has been developed. gem ‐Bis(dihydrosilyl)alkanes containing four silicon‐hydrogen bonds are efficiently constructed in an atom‐economical manner. Tolerated substrates include simplest alkyne‐ethyne, a complicated drug derivative and various functionalized terminal aliphatic alkynes. Asymmetric approach using two catalysts is achieved with excellent enantioselectivities to access corresponding chiral products. The transformations of Si—H bonds into Si—C, Si—O, and Si—F bonds and the synthesis of enantioriched α ‐hydroxysilane show synthetic utility.
Type of Medium:
Online Resource
ISSN:
1001-604X
,
1614-7065
DOI:
10.1002/cjoc.201900079
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
2144352-X
SSG:
6,25
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