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  • 2020-2024  (6)
  • Asia - CrossAsia  (6)
  • 1
    Online Resource
    Online Resource
    Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring
    IOP Publishing ; 2021
    In:  Research in Astronomy and Astrophysics Vol. 21, No. 3 ( 2021-04-01), p. 070-
    Details
    In: Research in Astronomy and Astrophysics, IOP Publishing, Vol. 21, No. 3 ( 2021-04-01), p. 070-
    Abstract: We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846–031 during its outburst in 2019 with the observations of Insight -HXMT, NICER and MAXI . This outburst can be classified roughly into four different states. Type-C quasi-periodic oscillations (QPOs) observed by NICER (about 0.1–6 Hz) and Insight -HXMT (about 0.7–8 Hz) are also reported in this work. Meanwhile, we study various physical quantities related to QPO frequency. The QPO rms–frequency relationship in the energy band 1–10 keV indicates that there is a turning pointing in frequency around 2 Hz, which is similar to that of GRS 1915+105. A possible hypothesis for the relationship above may be related to the inclination of the source, which may require a high inclination to explain it. The relationships between QPO frequency and QPO rms, hardness, total fractional rms and count rate have also been found in other transient sources, which can indicate that the origin of type–C QPOs is non-thermal.
    Type of Medium: Online Resource
    ISSN: 1674-4527
    URL: Article
    DOI: 10.1088/1674-4527/21/3/70
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2021
    detail.hit.zdb_id: 2511247-8
    SSG: 6,25
    SSG: 16,12
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  • 2
    Online Resource
    Online Resource
    LAMOST Time-Domain survey: first results of four K2 plates
    IOP Publishing ; 2021
    In:  Research in Astronomy and Astrophysics Vol. 21, No. 11 ( 2021-12-01), p. 292-
    Details
    In: Research in Astronomy and Astrophysics, IOP Publishing, Vol. 21, No. 11 ( 2021-12-01), p. 292-
    Abstract: From Oct. 2019 to Apr. 2020, LAMOST performed a time-domain (TD) spectroscopic survey of four K2 plates with both low- and medium-resolution observations. The low-resolution spectroscopic survey acquired 282 exposures ( ≈ 46.6 h) over 25 nights, yielding a total of about 767 000 spectra, and the medium-resolution survey took 177 exposures ( ≈ 49.1 h) over 27 nights, collecting about 478 000 spectra. More than 70%/50% of low-resolution/medium-resolution spectra have signal-to-noise ratio higher than 10. We determine stellar parameters (e.g., T eff , log  g , [Fe/H]) and radial velocity (RV) with different methods, including LASP, DD-Payne and SLAM. In general, these parameter estimations from different methods show good agreement, and the stellar parameter values are consistent with those of APOGEE. We use the Gaia DR2 RV values to calculate a median RV zero point (RVZP) for each spectrograph exposure by exposure, and the RVZP-corrected RVs agree well with the APOGEE data. The stellar evolutionary and spectroscopic masses are estimated based on the stellar parameters, multi-band magnitudes, distances and extinction values. Finally, we construct a binary catalog including about 2700 candidates by analyzing their light curves, fitting the RV data, calculating the binarity parameters from medium-resolution spectra and cross-matching the spatially resolved binary catalog from Gaia EDR3. The LAMOST TD survey is expected to represent a breakthrough in various scientific topics, such as binary systems, stellar activity, stellar pulsation, etc.
    Type of Medium: Online Resource
    ISSN: 1674-4527
    URL: Article
    DOI: 10.1088/1674-4527/21/11/292
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2021
    detail.hit.zdb_id: 2511247-8
    SSG: 6,25
    SSG: 16,12
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  • 3
    Online Resource
    Online Resource
    Exploring the impact of pericentric inversion of chromosome 9 on fertility in sperm donors
    Medknow ; 2024
    In:  Asian Journal of Andrology
    Details
    In: Asian Journal of Andrology, Medknow
    Abstract: Pericentric inversion of chromosome 9 (inv[9]) is a common chromosomal structural variant, but its impact on clinical outcomes remains debated. The screening criteria of sperm banks are rarely mentioned to individuals with inv(9). In this study, we evaluated the fertility of sperm donors with inv(9) who met eligibility criteria for sperm banks (inv[9] -eligible donors). From March 2004 to May 2022, chromosomal analysis of 16 124 sperm donors at CITIC-Xiangya Human Sperm Bank in Hunan Province (Changsha, China) found that 251 (1.6%) had chromosome variations, with inv(9) being the most prevalent at 1.1%. All 169 inv(9)-eligible donors were contacted to collect fertility outcome data, along with 206 eligible donors without inv(9) as controls. In addition, semen samples from inv(9)-eligible donors and eligible donors underwent assessments of sperm fluorescence in situ hybridization (FISH), mitochondrial membrane potential, DNA fragmentation index, acrosome integrity, reactive oxygen species (ROS), and sperm morphology. Results showed that inv(9) did not significantly increase reproductive risks overall. Despite detecting ROS level differences, the clinical impact may be insignificant. This study provides new data on the inv(9) population that can serve as a valuable reference for decision-making by sperm banks as well as for genetic counseling and clinical guidance for individuals carrying inv(9) variant.
    Type of Medium: Online Resource
    ISSN: 1745-7262 , 1008-682X
    URL: Article
    DOI: 10.4103/aja202369
    Language: English
    Publisher: Medknow
    Publication Date: 2024
    detail.hit.zdb_id: 2085228-9
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  • 4
    Online Resource
    Online Resource
    Astronomical Site Monitoring System at Lijiang Observatory
    IOP Publishing ; 2020
    In:  Research in Astronomy and Astrophysics Vol. 20, No. 9 ( 2020-09-01), p. 149-
    Details
    In: Research in Astronomy and Astrophysics, IOP Publishing, Vol. 20, No. 9 ( 2020-09-01), p. 149-
    Abstract: We installed two sets of Astronomical Site Monitoring Systems (ASMSs) at Lijiang Observatory (GMG), for the running of the 2.4-meter Lijiang optical telescope (LJT) and the 1.6-meter Multi-channel Photometric Survey Telescope (Mephisto). The Mephisto is under construction. The ASMS has been running on robotic mode since 2017. The core instruments: Cloud Sensor, All-Sky Camera and Autonomous-DIMM that are developed by our group, together with the commercial Meteorological Station and Sky Quality Meter, are combined into the astronomical optical site monitoring system. The new Cloud Sensor’s Cloud-Clear Relationship is presented for the first time, which is used to calculate the All-Sky cloud cover. We designed the Autonomous-DIMM located on a tower, with the same height as LJT. The seeing data have been observed for a full year. ASMS’s data for the year 2019 are also analysed in detail, which are valuable to observers.
    Type of Medium: Online Resource
    ISSN: 1674-4527
    URL: Article
    DOI: 10.1088/1674-4527/20/9/149
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2020
    detail.hit.zdb_id: 2511247-8
    SSG: 6,25
    SSG: 16,12
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  • 5
    Online Resource
    Online Resource
    Mis-estimation of coronary lesions and rectification by SYNTAX score feedback for coronary revascularization appropriateness
    Ovid Technologies (Wolters Kluwer Health) ; 2020
    In:  Chinese Medical Journal Vol. 133, No. 11 ( 2020-06-5), p. 1276-1284
    Details
    In: Chinese Medical Journal, Ovid Technologies (Wolters Kluwer Health), Vol. 133, No. 11 ( 2020-06-5), p. 1276-1284
    Abstract: Imprecise interpretation of coronary angiograms was reported and resulted in inappropriate revascularization. Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score is a comprehensive system to evaluate the complexity of the overall lesions. We hypothesized that a real-time SYNTAX score feedback from image analysts may rectify the mis-estimation and improve revascularization appropriateness in patients with stable coronary artery disease (CAD). Methods: In this single-center, historical control study, patients with stable CAD with coronary lesion stenosis ≥50% were consecutively recruited. During the control period, SYNTAX scores were calculated by treating cardiologists. During the intervention period, SYNTAX scores were calculated by image analysts immediately after coronary angiography and were provided to cardiologists in real-time to aid decision-making. The primary outcome was revascularization deemed inappropriate by Chinese appropriate use criteria for coronary revascularization. Results: A total of 3245 patients were enrolled and assigned to the control group (08/2016–03/2017, n  = 1525) or the intervention group (03/2017–09/2017, n  = 1720). For SYNTAX score tertiles, 17.9% patients were overestimated and 4.3% were underestimated by cardiologists in the control group. After adjustment, inappropriate revascularization significantly decreased in the intervention group compared with the control group (adjusted odds ratio [OR]: 0.83; 95% confidence interval [CI] : 0.73–0.95; P  = 0.007). Both inappropriate percutaneous coronary intervention (adjusted OR: 0.82; 95% CI: 0.74–0.92; P   〈  0.001) and percutaneous coronary intervention utilization (adjusted OR: 0.88; 95% CI: 0.79–0.98; P  = 0.016) decreased significantly in the intervention group. There was no significant difference in 1-year adverse cardiac events between the control group and the intervention group. Conclusions: Real-time SYNTAX score feedback significantly reduced inappropriate coronary revascularization in stable patients with CAD. Clinical trial registration: Nos. NCT03068858 and NCT02880605; https://www.clinicaltrials.gov.
    Type of Medium: Online Resource
    ISSN: 0366-6999 , 2542-5641
    URL: Article
    DOI: 10.1097/CM9.0000000000000827
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2020
    detail.hit.zdb_id: 2108782-9
    SSG: 6,25
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  • 6
    Online Resource
    Online Resource
    Modulatory effect of aquaporin 5 on estrogen-induced epithelial-mesenchymal transition in prostate epithelial cells
    Ovid Technologies (Wolters Kluwer Health) ; 2020
    In:  Chinese Medical Journal Vol. 134, No. 4 ( 2020-10-5), p. 448-455
    Details
    In: Chinese Medical Journal, Ovid Technologies (Wolters Kluwer Health), Vol. 134, No. 4 ( 2020-10-5), p. 448-455
    Abstract: Estrogen is involved in the pathophysiological process of benign prostatic hyperplasia (BPH), in which epithelial-mesenchymal transition (EMT) plays an important role. Upregulation of aquaporin (AQP) 5, which is directly activated by estrogen, has been reported to promote EMT in multiple cells. This study aimed to examine the effects of AQP5 on estrogen-induced EMT in the prostate. Methods Normal prostate (NP) tissue samples without any histopathological changes and BPH tissue samples with pathologically confirmed hyperplasia were obtained. An EMT cell model was subsequently established by adding estradiol (E2) to RWPE-1 cells, after which AQP5 knockdown was performed. Tissue morphological and immunohistochemical features were examined using hematoxylin-eosin and immunohistochemical staining. Western blot analysis was performed to determine the expression of AQPs, estrogen receptors, and EMT-related proteins. Cell proliferation was assessed and supernatants were collected for enzyme-linked immunosorbent assay to determine transforming growth factor-β1 (TGF-β1) concentrations. Immunofluorescence staining was performed to assess protein expressions in RWPE-1 cells. Results BPH tissues exhibited greater EMT (TGF-β1: 1.362 ± 0.196 vs. 0.107 ± 0.067, P  = 0.003; vimentin: 1.581 ± 0.508 vs. 0.221 ± 0.047, P   〈  0.001; E-cadherin: 0.197 ± 0.188 vs. 1.344 ± 0.088, P   〈  0.001), higher AQP5 (1.268 ± 0.136 vs. 0.227 ± 0.055, P   〈  0.001) and estrogen receptor (ER) α (1.250 ± 0.117 vs. 0.329 ± 0.134, P   〈  0.001) expression but lower ERβ (0.271 ± 0.184 vs. 1.564 ± 0.130, P   〈  0.001) expression than NP tissues. E2-stimulated cells had higher AQP5 expression (1.298 ± 0.058 vs. 1.085 ± 0.104, P  = 0.049), increased cell proliferation (1.510 ± 0.089 vs. 1.000 ± 0.038, P   〈  0.001), and EMT (TGF-β1 concentration: 0.352 ± 0.021 ng/mL vs. 0.125 ± 0.014 ng/mL, P   〈  0.001; vimentin: 1.641 ± 0.120 vs. 0.188 ± 0.020, P  = 0.002; E-cadherin: 0.075 ± 0.030 vs. 0.843 ± 0.046, P   〈  0.001) than controls. E2-stimulated cells with AQP5 knockdown exhibited decreased EMT (TGF-β1 concentration: 0.223 ± 0.041 ng/mL vs. 0.352 ± 0.021 ng/mL, P  = 0.016; vimentin: 0.675 ± 0.056 vs. 1.641 ± 0.120, P  = 0.001; E-cadherin: 0.159 ± 0.037 vs. 0.075 ± 0.030, P  = 0.040) than E2-stimulated cells with non-related small interfering RNA (siRNA). Conclusion Our findings suggest that estrogen induces BPH possibly by promoting AQP5 expression. Hence, AQP5 might be a novel target for modulating EMT in prostate epithelial cells.
    Type of Medium: Online Resource
    ISSN: 0366-6999 , 2542-5641
    URL: Article
    DOI: 10.1097/CM9.0000000000001132
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2020
    detail.hit.zdb_id: 2108782-9
    SSG: 6,25
    Location Call Number Limitation Availability
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