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Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors (2018)

Adam J. Meyer; Thomas H. Segall-Shapiro; Emerson Glassey; Jing Zhang; Christopher A. Voigt

Nature Publishing Group (NPG)

In: Nature Chemical Biology

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Publication Date: 2018-11-27

Description: Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors 〈i〉Escherichia〈/i〉 coli “Marionette” strains with 12 highly optimized small-molecule sensors, Published online: 26 November 2018; doi:10.1038/s41589-018-0168-3 A directed evolution approach was applied to optimize a set of 12 small-molecule-responsive biosensors, which led to the engineering of “Marionette” strains of Escherichia coli incorporating these sensors for biotechnological applications.

Print ISSN: 1552-4450

Electronic ISSN: 1552-4469

Topics: Biology , Chemistry and Pharmacology

Published by Nature Publishing Group (NPG)

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A method to rapidly create protein aggregates in living cells (2016)

Yusuke Miyazaki; Kota Mizumoto; Gautam Dey; Takamasa Kudo; John Perrino; Ling-chun Chen; Tobias Meyer; Thomas J. Wandless

Nature Publishing Group (NPG)

In: Nature Communications

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Publication Date: 2016-05-29

Description: Article Protein aggregates are associated with a wide variety of diseases. Here, in order to address how protein aggregation affects cellular homoeostasis, the authors describe a method to rapidly create protein aggregates in living cells and organisms with precise spatial and temporal control. Nature Communications doi: 10.1038/ncomms11689 Authors: Yusuke Miyazaki, Kota Mizumoto, Gautam Dey, Takamasa Kudo, John Perrino, Ling-chun Chen, Tobias Meyer, Thomas J. Wandless

Electronic ISSN: 2041-1723

Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General , Physics

Published by Nature Publishing Group (NPG)

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