Keywords:
Amyloid beta-protein.
;
Electronic books.
Description / Table of Contents:
Investigating a range of biological techniques to clarify the structure and function of this transmembrane protein, this text includes step-by-step protocols for each method, thus providing a framework for the study of other membrane proteins.
Type of Medium:
Online Resource
Pages:
1 online resource (244 pages)
Edition:
1st ed.
ISBN:
9780203492185
URL:
https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=2010215
DDC:
616.8047
Language:
English
Note:
Front cover -- Preface -- Contributors -- Table of Contents -- List of Antibodies to APP and A Proteins -- Chapter 1. Biochemical Characterization of Amyloid Precursor Protein -- Chapter 2. Assays for Analysis of APP Secretion and Recycling -- Chapter 3. Strategies for Crystallizing the N-Terminal Growth Factor Domain of Amyloid Precursor Protein -- Chapter 4. Analysis of Amyloid Precursor Protein Processing Protease -Secretase: Tools for Memapsin 2 ( -Secretase) Inhibition Studies -- Chapter 5. Assays for Amyloid Precursor Protein -Secretase Activity -- Chapter 6. Cell-Free Reconstitution of -Amyloid Production and Trafficking -- Chapter 7. Studying Amyloid -Protein Assembly -- Chapter 8. Intracecellular Accumulation of Amyloid and Mitochondrial Dysfunction in Down's Syndrome -- Chapter 9. Linking Alzheimer's Disease, -Amyloid, and Lipids: A Technical Approach -- Chapter 10. Regulation of Amyloid Precursor Protein Processing by Lithium -- Chapter 11. Immunocytochemical Analysis of Amyloid Precursor Protein and Its Derivatives -- Chapter 12. Pathological Detection of A and APP in Brain -- Chaptre 13. Creating APP Transgenic Lines in Mice -- Chapter 14. Generation of Amyloid Precursor Protein Knockout Mice -- Index -- Back cover.
