Publication Date:
2015-12-23
Description:
Nature Reviews Rheumatology 12, 25 (2016). doi:10.1038/nrrheum.2015.167 Authors: Daniella M. Schwartz, Michael Bonelli, Massimo Gadina & John J. O'Shea Cytokines are major drivers of autoimmunity, and biologic agents targeting cytokines have revolutionized the treatment of immune-mediated diseases. Despite the effectiveness of these drugs, they do not induce complete remission in all patients, prompting the development of alternative strategies — including targeting of intracellular signal
Topics:
Medicine