In:
BMC Bioinformatics, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2020-12)
Abstract:
Random forest based variable importance measures have become popular tools for assessing the contributions of the predictor variables in a fitted random forest. In this article we reconsider a frequently used variable importance measure, the Conditional Permutation Importance (CPI). We argue and illustrate that the CPI corresponds to a more partial quantification of variable importance and suggest several improvements in its methodology and implementation that enhance its practical value. In addition, we introduce the threshold value in the CPI algorithm as a parameter that can make the CPI more partial or more marginal. Results By means of extensive simulations, where the original version of the CPI is used as the reference, we examine the impact of the proposed methodological improvements. The simulation results show how the improved CPI methodology increases the interpretability and stability of the computations. In addition, the newly proposed implementation decreases the computation times drastically and is more widely applicable. The improved CPI algorithm is made freely available as an add-on package to the open-source software R. Conclusion The proposed methodology and implementation of the CPI is computationally faster and leads to more stable results. It has a beneficial impact on practical research by making random forest analyses more interpretable.
Type of Medium:
Online Resource
ISSN:
1471-2105
DOI:
10.1186/s12859-020-03622-2
Language:
English
Publisher:
Springer Science and Business Media LLC
Publication Date:
2020
detail.hit.zdb_id:
2041484-5
SSG:
12
